ISSN:
0030-4921
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Two mixed-acid lecithins: 1-stearoyl-2-linoleyl-sn-glycero-3-phosphorylcholine (SLL) and 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (SAL) have been synthesized by phospholipase A2 digestion of 1,2-distearoyl-sn-glycero-3-phosphorylcholine (DSL), followed by reacylation of the lysolecithin with the desired fatty acid anhydride. 13C (25.2 MHz) NMR spectra of SLL and SAL in CDCl3 solution and in sonicated dispersions in 2H2O have been obtained. Complete spectral assignments are reported for the two molecules in both systems. 13C nuclear spin-lattice relaxation times (T1) of SLL and SAL in sonicated aqueous dispersions have also been measured. Relaxation rate profiles as a function of the chain segment position are in general agreement with those recently obtained from 2H NMR for similar systems.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mrc.1270180211
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