ISSN:
1468-2494
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
The complex composition of lipstick formulations usually needs the use of organic solvents for sample dissolution. A treatment based on dissolution of cosmetic samples in ethanol-water (70 : 30, v/v) by use of ultrasonic irradiation is proposed. A C18 stationary phase and an isocratic mobile phase of ethanol:water:acetic acid (70 : 29.5 : 0.5, v/v/v) with a flow rate of 1 mL min−1 and an injection volume of 20 µL is proposed for the high-pressure liquid chromatography (HPLC) determination of four UV-filters, and detection was carried out at 309 nm. The limit of the chromatographic detection was 7.0 µg mL−1 for butyl methoxydibenzoylmethane, 1.5 µg mL−1 for benzophenone-3, 1.4 µg mL−1 for octyl dimethyl p-aminobenzoic acid (octyl dimethyl PABA) and 2.7 µg mL−1 for octyl methoxycinnamate. The relative standard deviations of the results were between 1.8 and 2.4%. The results were comparable to those obtained by a procedure based on the use of tetrahydrofuran. The method can be considered as a green analytical procedure because it only requires the use of small quantities of ethanol.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1046/j.1467-2494.2003.00178.x
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