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  • 1
    Online Resource
    Online Resource
    Milton : Taylor & Francis Group
    Keywords: Electronic books
    Description / Table of Contents: Cover -- Half Title -- Title -- Copyright -- Table of Contents -- List of figures -- List of contributors -- Acknowledgements -- Everyday automation: Setting a research agenda -- PART I Challenging dominant narratives of automation -- 1 Imagining mundane automation: Historical trajectories of meaning-making around technological change -- 2 Trust, ethics and automation: Anticipatory imaginaries in everyday life -- 3 The quantified pandemic: Digitised surveillance, containment and care in response to the COVID-19 crisis -- 4 Less work for teacher? The ironies of automated decision-making in schools -- PART II Embedding automated systems in the everyday -- 5 Alexa's got a Hunch: The human decisions behind programming emotion-sensing and caregiving into digital assistants -- 6 Framing fashion: Human-machine learning and the Amazon Echo Look -- 7 Coffee with the algorithm: Imaginaries, maintenance and care in the everyday life of a news-ranking algorithm -- 8 Everyday AI at work: Self-tracking and automated communication for smart work -- 9 Exploring ADM in clinical decision-making: Healthcare experts encountering digital automation -- PART III Experimenting with automation in society -- 10 Hate it? Automate it!: Thinking and doing robotic process automation and beyond -- 11 Smart thermostats and the algorithmic control of thermal comfort -- 12 Prisoners training AI: Ghosts, humans and values in data labour -- 13 Investigating ADM in shared mobility: A design ethnographic approach -- 14 Ad accountability online: A methodological approach -- Index.
    Type of Medium: Online Resource
    Pages: 1 online resource (251 pages)
    ISBN: 9781000583359
    Language: English
    Note: Description based on publisher supplied metadata and other sources
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  • 2
    Online Resource
    Online Resource
    Milton : Taylor & Francis Group
    Keywords: Electronic books
    Type of Medium: Online Resource
    Pages: 1 online resource (172 pages)
    ISBN: 9781000185294
    DDC: 303.4834
    Language: English
    Note: Description based on publisher supplied metadata and other sources
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Freshwater biology 25 (1991), S. 0 
    ISSN: 1365-2427
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: SUMMARY 1. Secondary production of chironomids (Diptera: Chironomidae) in a third-order northern Indiana stream was estimated using species-specific, and in most cases cohort-specific, life-history data from the field.2. Chironomid life-history patterns were diverse, ranging from one to four generations per year in addition to asynchronous development. Cohort production intervals (CPI) for all taxa ranged from 56 to 266 days. CPI for cohorts of conspecifics differed up to 3-fold.3. Annual secondary production was estimated using the instantaneous growth method or the size—frequency method depending on whether cohorts were distinguishable or not. Total annual chironomid production was 29 700 mg dry mass m−2, which is the highest value reported for chironomids from a north temperate stream.4. Eighty per cent of the total chironomid production was attributed to five species: Diamesa nivoriunda (33.9%), Cricotopus bicinctus (16.6%), Pagastia sp. (10.2%), C. trifascia (9.7%) and Orthodadius obumbratus (9.6%).5. The annual P:B ratio ranged from 4.7 to 21.9. Thus, high secondary production was due to high mean annual standing stocks and not to rapid biomass turnover.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 398 (1982), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract In the period 1980 to 1982, nineteen CormorantsPhalacrocorax carbo, three Grey HeronsArdea cinerea and one Great Crested GrebePodiceps crisatus were collected in The Netherlands. The livers of these fish-eating birdspecies were analyzed for polychlorinated dibenzo-p-dioxins and dibenzofurans. Only congeners with a 2,3,7,8-chlorine substitution pattern were found in the livers. Major components were 2,3,4,7,8-pentachlorodibenzofuran and 1,2,3,6,7,8-hexachlorodibenzo-p-dioxin, 2,3,7,8-tetrachlorodibenzo-p-dioxin and 1,2,3,7,8-pentachlorodibenzo-p-dioxin were also present. Six pooled samples of the EelAnguilla anguilla, showed the same congeneric pattern of chemicals as found in these bird species. In the Eel, 2,3,4,7,8-pentachlorodibenzofuran and 1,2,3,6,7,8-hexachlorodibenzo-p-dioxin were generally present in the 1 to 5 ng/kg range. Since the Eel is the Cormorant's 2 major food, this indicates strong bioaccumulation for both congeners in the liver of the Cormorant. Significant correlations were found between the various congeners retained in the liver of the Cormorant. It is proposed that this is a result of a continous exposure to a relatively stable background mixture, probably originating from fish consumption. Based on the congeneric patterns found in the Cormorant, polychlorinated biphenyls and pentachlorophenol are suggested as major contaminating sources for this species. Based on the results from the Cormorants, an open one compartment model was applied to estimate concentrations of 2,3,4,7,8-PnCDF in the Eel. These calculations were in good agreement with the actual measurements found in the Eels.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-0738
    Keywords: Polychlorinated dibenzo-p-dioxins, PCDDs ; Polychlorinated dibenzofurans, PCDFs ; Polychlorinated biphenyls, PCBs ; Mixtures ; Toxicokinetics ; Interactions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Six groups of C57BL/6J mice received single oral doses of 1.5–10.6 nmol/kg 1,2,3,7,8-pentachlorodibenzo-p-dioxin (PnCDD), 1,2,3,6,7,8-hexachlorodibenzo-p-dioxin (HxCDD) or 2,3,4,7,8-pentachlorodibenzofuran (PnCDF) as single compounds or in combination with 300 μmol/kg 2,2′,4,4′,5,5′-hexachlorobiphenyl (HxCB). Two other groups of mice received a mixture of the first three compounds, either with or without HxCB. The hepatic deposition and elimination of the compounds and their CYP1a dependent 7-ethoxyresorufin-O-deethylation (EROD) activity were studied until day 175. Interactive effects on the hepatic deposition of PnCDD were observed in most of the mixed dose groups. For HxCDD and PnCDF interactive effects were either very small or absent. No interactive effects were observed on hepatic elimination rates of PnCDD, HxCDD or PnCDF. No evidence was found for the influence of HxCB cotreatment on the hepatic concentration-response curves of the three compounds or their mixture. Based on the results from the present study it is concluded that PCDDs, PCDFs and PCBs may influence each other's, toxicokinetics when administered in mixtures.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-0738
    Keywords: Key words 2 ; 3 ; 7 ; 8-Tetrachlorodibenzo-p-dioxin ; TCDD ; 2 ; 3 ; 7 ; 8-Tetrachlorodibenzofuran ; TCDF ; 3 ; 3′ ; 4 ; 4′ ; 5-Pentachlorobiphenyl ; 2 ; 3 ; 4 ; 4′ ; 5-Pentachlorobiphenyl ; PCB ; In vitro ; Relative potency
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In vitro induction of ethoxyresorufin O-deethylase (EROD) activity in cell cultures is an extensively validated tool for measuring overall potencies of mixtures of halogenated aromatic hydrocarbons (HAHs) in samples from the abiotic or biotic environment. For risk assessment with special attention to effects in wild birds, an assay was developed that makes use of chicken embryo hepatocytes. However, it was questioned whether compound-specific responses are consistent at the various developmental stages. The results of our present study show that there are considerable differences between early and late embryonal and post-hatching stages. The induction of EROD was measured in primary chicken hepatocyte cultures. The cells were isolated at day 14 and day 19 of embryonal development and at day 1 post hatching. Hepatocytes were exposed in vitro to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), 2,3,7,8-tetrachlorodibenzofuran (TCDF), 3,3′,4,4′,5-pentachlorobiphenyl (PCB 126, IUPAC nomenclature) and 2,3′,4,4′,5-pentachlorobiphenyl (PCB 118). The respective compounds were chosen as representives for dioxins, furans, non-ortho PCBs, and mono-ortho PCBs. These groups of chemicals have been identified as environmental contaminants with major dioxin-like effects that are mediated by a common receptor, the arylhydrocarbon (Ah) receptor. At all developmental stages, TCDF was more potent than TCDD. Relative potencies (RP = EC50tcdd/EC50hah) decreased in the order TCDF〈TCDD〈 PCB 126〈PCB 118. Depending on the developmental stage, TCDF was 1.2 to 3.4 times more potent than TCDD. PCB 126 was equipotent or less potent by a factor of 3 than TCDD. PCB 118 was 100 to 300 times less potent than TCDD. Both the mean effective concentration (EC50) and the maximum EROD activity (Y max) of all compounds were lower in hepatocyte cultures from 14-day-old embryos than those from 19-day-old embryos or 1-day-old hatchlings. RPs were comparable in 19-day-old embryos and in hatchlings, but significantly different in 14-day-old embryos.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-0738
    Keywords: Polychlorinated biphenyls, PCBs ; Mixtures ; Toxicokinetics ; Interactions ; Potentiation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract 2,2′,4,4′,5,5′- (PCB 153), 2,3,3′,4,4′,5- (PCB 156) and 3,3′,4,4′,5,5′-hexachlorobiphenyl (PCB 169) were administered orally to three groups of C57BL/6J mice using single doses of 1.5–109.1 mg/kg. Two other groups of mice received binary mixtures of PCB 153 and 156 or PCB 153 and 169. The hepatic deposition, elimination, CYP1a and CYP2b dependent enzyme activities were studied during a 77-day period. Some interactive effects on hepatic deposition and elimination were observed, resulting in increased deposition and faster elimination. These effects were most pronounced for the PCBs 156 and 169. A potentiating effect on hepatic CYP1a dependent 7-ethoxyresorufin-O-deethylation (EROD) activity was observed for the combination of PCB 156 and 153. Based on the results from the present study and earlier studies, it is suggested that the potentiating effect on EROD activity might be caused by a mechanism that is governed by at least two factors. The first is a toxicokinetic modulation of hepatic retention. The second factor is probably an elevation of hepatic Ah receptor levels by PCB 153.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Fresenius' Zeitschrift für analytische Chemie 348 (1994), S. 106-110 
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary Polyhalogenated aromatic hydrocarbons (PHAH) are wide spread, highly toxic, environmental contaminants. As such they pose risks for both humans and wildlife. For risk assessment purposes, concentrations are generally analyzed by HRGC-HR/LRMS. With the analytical data, mixture toxicity is calculated using the TEF concept. With this method only the defined congeners are taken into account and additivity for all congeners is assumed, whereas synergistic and antagonistic effects for several PCDD/F in combination with PCB have also been reported. To avoid these problems and high analytical costs, bioassays can be used for screening purposes. Cytochrome P450 1 A 1 induction and vitamin A and thyroid hormone levels are shown to be useful markers for PHAH exposure. When bioassays based on cytochrome P450 1A1 induction, in cultured cells, in multi-well culturing plates, are used, 2,3,7,8-TCDD detection limits 〈0.2 pg are possible. As such these bioassays are highly sensitive, cost effective and time saving. This application can be used as a pre-screening method to determine total “dioxin” content of environmental samples.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Aquatic ecology 26 (1992), S. 471-476 
    ISSN: 1573-5125
    Keywords: chironomids ; secondary production ; Allen paradox ; streams
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Chironomid secondary production was estimated on a species-specific basis for 14 dominant taxa in a third-order woodland stream. Results from this study were used to provide an expalanation for the common observation that benthos secondary production in streams is insufficient to account for levels of fish production,i.e., the ALLEN paradox. Annual chironomid secondary production was 29.7 g dry mass m−2 and accounted for 80% of the total aquatic insect secondary production. A contribution by chironomids this high has not been reported previously from similar streams and indicates that chironomids are an energetically important group available for fish consumption. Most studies examining chironomid secondary production group all taxa at the family level and calculate secondary production for the entire family using the size-frequency method. This approach violates assumptions of the size-frequency method and will result in inaccurate and unpredictable estimates of chironomid secondary production. The species-specific approach to estimate chironomid production used in this study, combined with non-chironomid production, yielded a benthos annual production rate that exceeded consumption necessary to support fish production.
    Type of Medium: Electronic Resource
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