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  • 1
    Electronic Resource
    Electronic Resource
    Posttraumatic nonunion of the clavicle in a 7-year-old girl (1998)
    Springer
    Archives of orthopaedic and trauma surgery 117 (1998), S. 475-476 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract An unusual case is reported of posttraumatic nonunion of the clavicle in a 7-year-old girl, which was treated by surgical stabilization with a Kirschner wire and apposition of cancellous bone chips taken from the proximal right tibial metaphysis. At clinical examination 2 years after surgery, the patient was symptomfree, and she had a full range of motion of the shoulder. Radiographs showed a very good remodeling of the bone, with only a minimal difference between the two clavicles.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004020050297
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Haemangiopericytoma in the distal third of the arm (1999)
    Springer
    International orthopaedics 23 (1999), S. 184-186 
    Details
    ISSN: 1432-5195
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé  Présentation d’un cas d’hémangiopéricytome du tiers distal du bras chez une femme de 49 ans. Une résection large a été faite. Il n’y a pas de récidive au recul de 5 ans.
    Notes: Abstract  A 49-year-old woman had a haemangiopericytoma in the distal third of the arm, which is an extremely rare location. There was no recurrence of the tumor 5 years after wide margin surgical excision.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002640050343
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    Paper (German National Licenses)
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  • 3
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    A benchmark study of numerical implementations of the sea level equation in GIA modelling (2018)
    Oxford Univ. Press
    In:  Geophysical Journal International, 215 (1). pp. 389-414.
    Details
    Publication Date: 2021-02-08
    Description: The ocean load in glacial isostatic adjustment (GIA) modelling is represented by the so-called sea level equation (SLE). The SLE describes the mass redistribution of water between ice sheets and oceans on a deforming Earth. Despite various teams independently investigating GIA, there has been no systematic intercomparison among the numerical solvers of the SLE through which the methods may be validated. The goal of this paper is to present a series of synthetic examples designed for testing and comparing the numerical implementations of the SLE in GIA modelling. The 10 numerical codes tested combine various temporal and spatial parametrizations. The time-domain or Laplace-domain discretizations are used to solve the SLE through time, while spherical harmonics, finite differences or finite elements parametrize the GIA-related field variables spatially. The surface ice-water load and solid Earth’s topography are represented spatially either on an equiangular grid, a Gauss–Legendre or an equiarea grid with icosahedron-shaped spherical pixels. Comparisons are made in a series of five benchmark examples with an increasing degree of complexity. Due to the complexity of the SLE, there is no analytical solution to it. The accuracy of the numerical implementations is therefore assessed by the differences of the individual solutions with respect to a reference solution. While the benchmark study does not result in GIA predictions for a realistic loading scenario, we establish a set of agreed-upon results that can be extended in the future by including more complex case studies, such as solutions with realistic loading scenarios, the rotational feedback in the linear-momentum equation, and by considering a 3-D viscosity structure of the Earth’s mantle. The test computations performed so far show very good agreement between the individual results and their ability to capture the main features of sea-surface variation and the surface vertical displacement. The differences found can often be attributed to the different approximations inherent in the various algorithms. This shows the accuracy that can be expected from different implementations of the SLE, which helps to assess differences noted in the literature between predictions for realistic loading cases.
    Type: Article , PeerReviewed
    Format: text
    DOI: 10.1093/gji/ggy280
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    OceanRep: Article in a Scientific Journal - peer-reviewed
  • 4
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    Uplift rates from a new high-density GPS network in Palmer Land indicate significant late Holocene ice loss in the southwestern Weddell Sea (2015)
    Oxford University Press
    Details
    Publication Date: 2015-09-06
    Description: The measurement of ongoing ice-mass loss and associated melt water contribution to sea-level change from regions such as West Antarctica is dependent on a combination of remote sensing methods. A key method, the measurement of changes in Earth's gravity via the GRACE satellite mission, requires a potentially large correction to account for the isostatic response of the solid Earth to ice-load changes since the Last Glacial Maximum. In this study, we combine glacial isostatic adjustment modelling with a new GPS dataset of solid Earth deformation for the southern Antarctic Peninsula to test the current understanding of ice history in this region. A sufficiently complete history of past ice-load change is required for glacial isostatic adjustment models to accurately predict the spatial variation of ongoing solid Earth deformation, once the independently-constrained effects of present-day ice mass loss have been accounted for. Comparisons between the GPS data and glacial isostatic adjustment model predictions reveal a substantial misfit. The misfit is localized on the southwestern Weddell Sea, where current ice models under-predict uplift rates by approximately 2 mm yr –1 . This under-prediction suggests that either the retreat of the ice sheet grounding line in this region occurred significantly later in the Holocene than currently assumed, or that the region previously hosted more ice than currently assumed. This finding demonstrates the need for further fieldwork to obtain direct constraints on the timing of Holocene grounding line retreat in the southwestern Weddell Sea and that GRACE estimates of ice sheet mass balance will be unreliable in this region until this is resolved.
    Keywords: Gravity, Geodesy and Tides
    Print ISSN: 0956-540X
    Electronic ISSN: 1365-246X
    Topics: Geosciences
    Published by Oxford University Press on behalf of The Deutsche Geophysikalische Gesellschaft (DGG) and the Royal Astronomical Society (RAS).
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  • 5
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    A benchmark study for glacial isostatic adjustment codes (2011)
    Oxford University Press
    Details
    Publication Date: 2011-02-22
    Description: SUMMARY The study of glacial isostatic adjustment (GIA) is gaining an increasingly important role within the geophysical community. Understanding the response of the Earth to loading is crucial in various contexts, ranging from the interpretation of modern satellite geodetic measurements (e.g. GRACE and GOCE) to the projections of future sea level trends in response to climate change. Modern modelling approaches to GIA are based on various techniques that range from purely analytical formulations to fully numerical methods. Despite various teams independently investigating GIA, we do not have a suitably large set of agreed numerical results through which the methods may be validated; a community benchmark data set would clearly be valuable. Following the example of the mantle convection community, here we present, for the first time, the results of a benchmark study of codes designed to model GIA. This has taken place within a collaboration facilitated through European Cooperation in Science and Technology (COST) Action ES0701. The approaches benchmarked are based on significantly different codes and different techniques. The test computations are based on models with spherical symmetry and Maxwell rheology and include inputs from different methods and solution techniques: viscoelastic normal modes, spectral-finite elements and finite elements. The tests involve the loading and tidal Love numbers and their relaxation spectra, the deformation and gravity variations driven by surface loads characterized by simple geometry and time history and the rotational fluctuations in response to glacial unloading. In spite of the significant differences in the numerical methods employed, the test computations show a satisfactory agreement between the results provided by the participants.
    Print ISSN: 0956-540X
    Electronic ISSN: 1365-246X
    Topics: Geosciences
    Published by Oxford University Press on behalf of The Deutsche Geophysikalische Gesellschaft (DGG) and the Royal Astronomical Society (RAS).
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  • 6
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    Observed rapid bedrock uplift in Amundsen Sea Embayment promotes ice-sheet stability (2018)
    American Association for the Advancement of Science (AAAS)
    In: Science
    Details
    Publication Date: 2018-06-22
    Description: The marine portion of the West Antarctic Ice Sheet (WAIS) in the Amundsen Sea Embayment (ASE) accounts for one-fourth of the cryospheric contribution to global sea-level rise and is vulnerable to catastrophic collapse. The bedrock response to ice mass loss, glacial isostatic adjustment (GIA), was thought to occur on a time scale of 10,000 years. We used new GPS measurements, which show a rapid (41 millimeters per year) uplift of the ASE, to estimate the viscosity of the mantle underneath. We found a much lower viscosity (4 x 10 18 pascal-second) than global average, and this shortens the GIA response time scale from tens to hundreds of years. Our finding requires an upward revision of ice mass loss from gravity data of 10% and increases the potential stability of the WAIS against catastrophic collapse.
    Keywords: Oceanography
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Geosciences , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 7
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    Relationship between Prolactin Plasma Levels and White Matter Volume in Women with Multiple Sclerosis (2015)
    Hindawi
    Details
    Publication Date: 2015-07-09
    Description: Background. The role of prolactin (PRL) on tissue injury and repair mechanisms in multiple sclerosis (MS) remains unclear. The aim of this work was to investigate the relationship between PRL plasma levels and brain damage as measured by magnetic resonance imaging (MRI). Methods. We employed a chemiluminescence immunoassay for measuring plasma levels of PRL. We used a 1.5 T scanner to acquire images and Jim 4.0 and SIENAX software to analyse them. Results. We included 106 women with relapsing remitting (RR) MS and stable disease in the last two months. There was no difference in PRL plasma levels between patients with and without gadolinium enhancement on MRI. PRL plasma levels correlated with white matter volume (WMV) (rho = 0.284, ) but not with grey matter volume (GMV). Moreover, PRL levels predicted changes in WMV (Beta: 984, ). Conclusions. Our data of a positive association between PRL serum levels and WMV support the role of PRL in promoting myelin repair as documented in animal models of demyelination. The lack of an increase of PRL in the presence of gadolinium enhancement, contrasts with the view considering this hormone as an immune-stimulating and detrimental factor in the inflammatory process associated with MS.
    Print ISSN: 0962-9351
    Electronic ISSN: 1466-1861
    Topics: Medicine
    Published by Hindawi
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  • 8
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    Asymptomatic Takayasu Aortitis Complicated by Type B Dissection [Images in Cardiovascular Medicine] (2015)
    American Heart Association (AHA)
    Details
    Publication Date: 2015-12-02
    Keywords: Computerized Tomography (CT), Functional Magnetic Resonance Imaging (fMRI)
    Electronic ISSN: 1524-4539
    Topics: Medicine
    Published by American Heart Association (AHA)
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  • 9
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    An analytical solution for the elastic response to surface loads imposed on a layered, transversely isotropic and self-gravitating Earth (2015)
    Oxford University Press
    Details
    Publication Date: 2015-11-07
    Description: We present an analytical solution for the elastic deformation of an elastic, transversely isotropic, layered and self-gravitating Earth by surface loads. We first introduce the vector spherical harmonics to express the physical quantities in the layered Earth. This reduces the governing equations to a linear system of equations for the expansion coefficients. We then solve for the expansion coefficients analytically under the assumption (i.e. approximation) that in the mantle, the density in each layer varies as 1/ r (where r is the radial coordinate) while the gravity is constant and that in the core the gravity in each layer varies linearly in r with constant density. These approximations dramatically simplify the subsequent mathematical analysis and render closed-form expressions for the expansion coefficients. We implement our solution in a MATLAB code and perform a benchmark which shows both the correctness of our solution and the implementation. We also calculate the load Love numbers (LLNs) of the PREM Earth for different degrees of the Legendre function for both isotropic and transversely isotropic, layered mantles with different core models, demonstrating for the first time the effect of Earth anisotropy on the LLNs.
    Keywords: Gravity, Geodesy and Tides
    Print ISSN: 0956-540X
    Electronic ISSN: 1365-246X
    Topics: Geosciences
    Published by Oxford University Press on behalf of The Deutsche Geophysikalische Gesellschaft (DGG) and the Royal Astronomical Society (RAS).
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  • 10
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    Automatic identification of type 2 diabetes, hypertension, ischaemic heart disease, heart failure and their levels of severity from Italian General Practitioners' electronic medical records: a validation study (2016)
    BMJ Publishing
    In: BMJ Open
    Details
    Publication Date: 2016-12-11
    Description: Objectives The Italian project MATRICE aimed to assess how well cases of type 2 diabetes (T2DM), hypertension, ischaemic heart disease (IHD) and heart failure (HF) and their levels of severity can be automatically extracted from the Health Search/CSD Longitudinal Patient Database (HSD). From the medical records of the general practitioners (GP) who volunteered to participate, cases were extracted by algorithms based on diagnosis codes, keywords, drug prescriptions and results of diagnostic tests. A random sample of identified cases was validated by interviewing their GPs. Setting HSD is a database of primary care medical records. A panel of 12 GPs participated in this validation study. Participants 300 patients were sampled for each disease, except for HF, where 243 patients were assessed. Outcome measures The positive predictive value (PPV) was assessed for the presence/absence of each condition against the GP's response to the questionnaire, and Cohen's was calculated for agreement on the severity level. Results The PPV was 100% (99% to 100%) for T2DM and hypertension, 98% (96% to 100%) for IHD and 55% (49% to 61%) for HF. Cohen's kappa for agreement on the severity level was 0.70 for T2DM and 0.69 for hypertension and IHD. Conclusions This study shows that individuals with T2DM, hypertension or IHD can be validly identified in HSD by automated identification algorithms. Automatic queries for levels of severity of the same diseases compare well with the corresponding clinical definitions, but some misclassification occurs. For HF, further research is needed to refine the current algorithm.
    Keywords: Open access, Epidemiology, Health informatics, Public health
    Electronic ISSN: 2044-6055
    Topics: Medicine
    Published by BMJ Publishing
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