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  • 1
    Online Resource
    Online Resource
    Influence of Psycho-Sexual Factors on the Quality of Life of Iranian Infertile Women: A Path Analysis
    Informa UK Limited ; 2020
    In:  International Journal of Sexual Health Vol. 32, No. 3 ( 2020-07-02), p. 216-224
    Details
    In: International Journal of Sexual Health, Informa UK Limited, Vol. 32, No. 3 ( 2020-07-02), p. 216-224
    Type of Medium: Online Resource
    ISSN: 1931-7611 , 1931-762X
    URL: Article
    DOI: 10.1080/19317611.2020.1775748
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 2020
    SSG: 5,2
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  • 2
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    The effect of endometrial scratch injury on pregnancy outcome in women with previous intrauterine insemination failure: A randomized clinical trial
    Wiley ; 2017
    In:  Journal of Obstetrics and Gynaecology Research Vol. 43, No. 9 ( 2017-09), p. 1421-1427
    Details
    In: Journal of Obstetrics and Gynaecology Research, Wiley, Vol. 43, No. 9 ( 2017-09), p. 1421-1427
    Abstract: Endometrial scratch injury (ESI) has been recently proposed to enhance the implantation rate in assisted reproductive technology cycles. The present study was conducted to determine the effect of ESI on pregnancy rate in women with intrauterine insemination (IUI) failure. Methods This prospective randomized controlled study was carried out in Imam‐Khomeini Hospital and Royan Institute, Tehran, during a 12‐month period from January 2013 to January 2014. After assessment, 169 patients who had IUI failure twice or more (no chemical or clinical pregnancy) with normal uterine anatomy and hysterosalpingography, were enrolled. They were randomly assigned into two groups. In the experimental group, all patients underwent ESI at day 8 or 9 of stimulation phase in the present IUI cycle, whereas no intervention was performed on the control group. IUI outcome was then compared between the two groups. Results A total of 150 patients completed the IUI cycle during the study. The chemical pregnancy rate was 10.7% and 2.7% in the experimental and control groups, respectively, without significant difference ( P  = 0.09). Also no significant differences were detected in terms of clinical pregnancy and miscarriage rates between the two groups ( P   〉  0.05). Conclusions No significant beneficial effect of ESI on fertility outcome in patients with repeated IUI failure was detected when it was carried out on day 8 or 9 of the same IUI stimulation cycle. Also, however, no negative impact secondary to ESI was observed. Therefore, confirmation or refutation of this hypothesis requires further studies with a larger sample size. IRCT201507271141N19.
    Type of Medium: Online Resource
    ISSN: 1341-8076 , 1447-0756
    URL: Issue
    URL: Article
    DOI: 10.1111/jog.2017.43.issue-9
    DOI: 10.1111/jog.13401
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 2079101-X
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  • 3
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    The influence of mode of delivery, anthropometric indices, and infant's sex on the maternal and cord blood orexin‐A levels: A cohort study
    Wiley ; 2021
    In:  Journal of Obstetrics and Gynaecology Research Vol. 47, No. 7 ( 2021-07), p. 2363-2370
    Details
    In: Journal of Obstetrics and Gynaecology Research, Wiley, Vol. 47, No. 7 ( 2021-07), p. 2363-2370
    Abstract: Orexin as an adipokin hormone plays an important role in appetite regulation, energy metabolism, obesity, diabetes, and cardiovascular disease. The main source of orexin secretion in nonpregnant and pregnant women is adipose tissue and placenta, respectively. This research was conducted to evaluate the association between orexin‐A level and the mode of delivery, anthropometric indices, and sex of the infant. Methods This prospective cohort study was conducted on 69 normal pregnant women. The samples of umbilical cord blood were obtained at the time of delivery, and maternal blood was taken within 24 h of delivery. Serum orexin‐A levels were measured by using enzyme‐linked immunosorbent assay. Statistical analyses were performed using SPSS and p   〈  0.05 was considered as significant. Results We found a significant difference between postpartum maternal and umbilical cord orexin‐A level both with the mode of delivery ( p   〈  0.001). Also, a significant positive correlation was seen between maternal and umbilical cord serum orexin‐A levels ( r  = −0.61, p   〈  0.001). There was no relationship between serum orexin‐A levels with anthropometric indices and the sex of the neonate ( p   〉  0.05). Conclusion Both maternal and umbilical cord serum orexin‐A levels were associated with the mode of delivery. Maternal and cord blood orexin‐A levels in normal vaginal delivery are higher than cesarean section.
    Type of Medium: Online Resource
    ISSN: 1341-8076 , 1447-0756
    URL: Issue
    URL: Article
    DOI: 10.1111/jog.v47.7
    DOI: 10.1111/jog.14758
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 2079101-X
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  • 4
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    The association of food consumption and nutrient intake‎ with endometriosis risk in Iranian women: A case-control study
    Knowledge E DMCC ; 2019
    In:  International Journal of Reproductive BioMedicine ( 2019-09-22)
    Details
    In: International Journal of Reproductive BioMedicine, Knowledge E DMCC, ( 2019-09-22)
    Abstract: Background: Endometriosis, defined as the attendance of endometrial-like lesions in extra uterine locations, causes pain, infertility, and reduced quality of life. Objective: To evaluate the relationship between food consumption and nutrient intake with risk of endometriosis. Materials and Methods: Of the 156 women approached for the study, 78 women had endometriosis and 78 healthy women were included in the control group. Dietary data were collected using a validated 147-item semi-quantitative Food Frequency Questionnaire (FFQ) with the standard serving size. A logistic regression model was used to determine the association of macronutrients and energy intake with the risk of endometriosis. Results: In women with higher intake of protein, especially animal protein, monounsaturated fatty acids, soluble and insoluble fiber, oleic acid, eicosapentaenoic acid, and docosahexaenoic acid endometriosis is less common (p 〈 0.05). High consumption of vegetables, fruits, red meat, yellow vegetables, potatoes, legumes, dairy products, liquid oil, and low intake of fried potatoes was associated with a lower risk of endometriosis (p 〈 0.05). Conclusion: Regarding the association of dietary intake on endometriosis risk, counseling about improving the dietary structure can contribute toward the prevention and control of endometriosis. Key words: Endometriosis, Macronutrient, Diet, Case-control study.
    Type of Medium: Online Resource
    ISSN: 2476-3772 , 2476-4108
    URL: Article
    DOI: 10.18502/ijrm.v17i9.5102
    Language: Unknown
    Publisher: Knowledge E DMCC
    Publication Date: 2019
    detail.hit.zdb_id: 2898387-7
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  • 5
    Online Resource
    Online Resource
    Development and psychometric evaluation of the Sexual Health Assessment Tool for Infertile Women (SEHAT-IW)
    Springer Science and Business Media LLC ; 2021
    In:  Archives of Gynecology and Obstetrics Vol. 303, No. 2 ( 2021-02), p. 589-596
    Details
    In: Archives of Gynecology and Obstetrics, Springer Science and Business Media LLC, Vol. 303, No. 2 ( 2021-02), p. 589-596
    Type of Medium: Online Resource
    ISSN: 0932-0067 , 1432-0711
    URL: Article
    DOI: 10.1007/s00404-020-05832-8
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
    detail.hit.zdb_id: 1458450-5
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  • 6
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    Comparison of various aspects of women’s lives between infertile and women with and without tubal ligation: a comparative cross-sectional study
    Springer Science and Business Media LLC ; 2021
    In:  BMC Women's Health Vol. 21, No. 1 ( 2021-08-28)
    Details
    In: BMC Women's Health, Springer Science and Business Media LLC, Vol. 21, No. 1 ( 2021-08-28)
    Abstract: The aim of this study is to compare anxiety, depression, body image, self-esteem, sexual function, and quality of life (QoL) between infertile women and control fertile women undergoing tubal ligation (TL) and using condom. Methods This cross-sectional study was conducted on 600 women in three groups of infertile and control fertile women with or without TL (200 women in each group), who met the inclusion criteria. They were selected from Royan Institute and a number of health care centers in Tehran (Iran) from May 2017 to February 2019. The subjects were asked to fill out the Short Form Health Survey (SF-12), Female Sexual Function Index (FSFI), Hospital Anxiety and Depression Scale (HADS), Body Image Concern Inventory (BICI), and Rosenberg’ Self-Esteem Scale (RSES). One-way ANOVA was used to identify the possible statistical differences between the three groups of participants. Results The mean scores of all FSFI domains were lower in the control TL women, and the differences between the three groups in all dimensions were statistically significant. In addition, the TL group had more female sexual dysfunction (FSD) comparing to the infertile and condom group (22.43 ± 5.30, 24.79 ± 4.74, and 28.03 ± 3.29, respectively P   〈  0.001). There was a significant difference between the three groups in SF-12 scores (76.59 ± 13.14, 68.49 ± 14.47, and 78.87 ± 12.62, respectively P   〈  0.001). Also there was a significant difference between the three groups in anxiety, depression, and total scores of HADS ( P   〈  0.001). Furthermore, infertile women had lower body image ( P   〈  0.05) and the TL group had lower self-esteem comparing to the two other groups ( P   〈  0.05). Conclusions The findings revealed the adverse effects of using TL on the anxiety, depression, sexual life, body image, and QoL of women. It is recommended that health-care professionals should increase their awareness and knowledge regarding the side-effects of using TL on women’s lives and share this information with the patients.
    Type of Medium: Online Resource
    ISSN: 1472-6874
    URL: Article
    DOI: 10.1186/s12905-021-01454-7
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
    detail.hit.zdb_id: 2050444-5
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  • 7
    Online Resource
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    Association between dietary inflammatory index and endometriosis risk in a case-control study
    SAGE Publications ; 2021
    In:  Journal of Endometriosis and Pelvic Pain Disorders Vol. 13, No. 2 ( 2021-06), p. 77-82
    Details
    In: Journal of Endometriosis and Pelvic Pain Disorders, SAGE Publications, Vol. 13, No. 2 ( 2021-06), p. 77-82
    Abstract: Endometriosis is defined as the presence of functioning endometrial tissue in extra uterine structures that causes pain, infertility and reduced quality of life. Diet plays an important role in the modulation of endometriosis. Aim: This study aimed to evaluate the association between the dietary inflammatory index (DII) score and the endometriosis compared to healthy people in a case-control study in Iran. Methods: This study included 78 women with laparoscopically confirmed endometriosis and 78 women with normal pelvis. The DII was calculated from dietary intake assessed using a validated food frequency questionnaire. The association between DII scores (divided in tertiles) and endometriosis risk was investigated using logistic regression analysis and reported as odds ratios (ORs) and 95% confidence intervals (CI) adjusted for age, energy, BMI, education, para, smoking, pelvic pain, menorrhagia, stage of endometriosis, physical activity, and income. Results: In the age-adjusted models, subjects who consumed more pro-inflammatory diets (the upper tertile of DII) had an OR of 2.24 (95% CI = 2.03, 3.91) as compared to subjects in the lowest tertile. Also after multivariable adjustment, women in the highest tertile of DII (versus lowest tertile) were more likely to have endometriosis (OR 2.63; 95% CI 1.88–2.91, p = 0.004). Conclusion: Our results suggest that women with more consumption of pro-inflammatory diet were at increased endometriosis risk.
    Type of Medium: Online Resource
    ISSN: 2284-0265 , 2284-0273
    URL: Article
    DOI: 10.1177/2284026520984415
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2808441-X
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  • 8
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    Health related quality of life and psychological parameters in different polycystic ovary syndrome phenotypes: a comparative cross-sectional study
    Springer Science and Business Media LLC ; 2021
    In:  Journal of Ovarian Research Vol. 14, No. 1 ( 2021-12)
    Details
    In: Journal of Ovarian Research, Springer Science and Business Media LLC, Vol. 14, No. 1 ( 2021-12)
    Abstract: Polycystic Ovary Syndrome (PCOS) is associated with high levels of phsychological implications and detriments to Quality of Life (QoL). The aim of this study was to assess Health- Related Quality of Life (HRQoL), depression, and anxiety in Iranian women with different PCOS phenotypes. Methods The present observational, cross-sectional study was carried out on 239 PCOS women who were classified on the basis of Rotterdam criteria into four categories: A ( n  = 77), B ( n  = 38), C ( n  = 68), and D ( n  = 56). They asked to fill out three questionnaires, namely, HRQoL, SF-12, and HADS. Results No significant differences were observed between the four PCOS phenotypes for anxiety, depression and QoL, as well as HRQoL domains related to infertiliy, weight and emotional problems ( P   〉  0.05). Phenotypes A and B had worse HRQoL related to hirsutism (13.98 ± 5.22, 14.13 ± 6.23, P   〈  0.001). In addition, no significant differences were observed between them for HRQoL domains. While the score of acne in phenotype D (19.60 ± 5.12, P  = 0.003) and menstrual score in phenotype C were significantly higher comparing to the other PCOS groups (16.82 ± 3.87, P   〈  0.001). Conclusion Presenting similar psychological profiles in all phenotypes unveils the importance of pychological well-being screening, even in milder reproductive phenotypes.
    Type of Medium: Online Resource
    ISSN: 1757-2215
    URL: Article
    DOI: 10.1186/s13048-021-00811-2
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
    detail.hit.zdb_id: 2455679-8
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  • 9
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    A randomized trial assessing the efficacy of Silymarin on endometrioma-related manifestations
    Springer Science and Business Media LLC ; 2022
    In:  Scientific Reports Vol. 12, No. 1 ( 2022-10-20)
    Details
    In: Scientific Reports, Springer Science and Business Media LLC, Vol. 12, No. 1 ( 2022-10-20)
    Abstract: To study the effect of silymarin on the Interleukin-6 (IL-6) level, size of endometrioma lesion, pain, sexual function, and Quality of Life (QoL) in women diagnosed with endometriosis. This randomized, double-blind placebo-controlled clinical trial was performed on 70 women with endometriosis which was divided into two groups of intervention and control. The intervention was 140 mg silymarin (or matching placebo) administered twice daily for 12 weeks. The volume of endometrioma lesions, the level of IL-6 concentration in serum, pain, sexual function, and QoL were analyzed before and after the intervention. The means of endometrioma volume (P = 0.04), IL-6 (P = 0.002), and pain (P  〈  0.001) were reduced significantly in the silymarin group after intervention. However, the QoL and female sexual function did not improve substantially in the two groups (P  〉  0.05). Silymarin significantly reduced interleukin-6 levels, sizes of endometrioma lesions, and pain-related symptoms. The trial has been registered in the Iranian Registry of Clinical Trials (IRCT20150905023897N5) on 4th February 2020 (04/02/2020) ( https://en.irct.ir/trial/42215 ) and the date of initial participant enrollment was 2nd March 2020 (02/03/2020).
    Type of Medium: Online Resource
    ISSN: 2045-2322
    URL: Article
    DOI: 10.1038/s41598-022-22073-8
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 2615211-3
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  • 10
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    Comparison of the umbilical cord Blood’s anti-Mullerian hormone level in the newborns of mothers with polycystic ovary syndrome (PCOS) and healthy mothers
    Springer Science and Business Media LLC ; 2019
    In:  Journal of Ovarian Research Vol. 12, No. 1 ( 2019-12)
    Details
    In: Journal of Ovarian Research, Springer Science and Business Media LLC, Vol. 12, No. 1 ( 2019-12)
    Abstract: Polycystic ovary syndrome (PCOS) is one of the most common endocrine diseases. At present, the cause of the disease is not fully understood, but many studies have shown that PCOS is associated with genetic and environmental factors. The present study aimed to assess the umbilical cord blood’s Anti-mullerian hormone (AMH) level in the newborns of mothers suffering from PCOS comparing to healthy mothers. Methods This prospective cohort study was conducted on 120 pregnant women with PCOS, who were selected through Rotterdam criteria, and 60 healthy pregnant women as the control group. The subjects in each group were divided into obese and non-obese mothers according to their body mass index (BMI) before pregnancy. The cord blood samples were collected from the offsprings on the time of childbirth. Finally, the circulating concentrations of AMH in both sexes of the newborns were determined by specific assays. Results The research results showed that the blood level of AMH was higher in the neonates of obese mothers with PCOS comparing to the controls ( P   〈  0.001). Mean AMH level was higher in male neonates born from non-obese PCOS mothers than in the controls (P  〈  0.001); however, there was not a significant difference in the level of AMH in female neonates between these two groups ( P  = 0.264). Also the level of the above biomarker was higher in both sexes of the neonates belonging to obese PCOS mothers compared with the neonates born from non-obese PCOS mothers ( P   〈  0.001). Conclusion(s) It can be said that the cord blood AMH level of neonates from obese women with PCOS is higher than that in the newborns of non-obese PCOS mothers. Further longitudinal studies are needed to confirm the clinical findings of the present research.
    Type of Medium: Online Resource
    ISSN: 1757-2215
    URL: Article
    DOI: 10.1186/s13048-019-0583-4
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2019
    detail.hit.zdb_id: 2455679-8
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