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  • 1
    Online Resource
    Online Resource
    Surgical treatment of patients with infective endocarditis: changes in temporal use, patient characteristics, and mortality—a nationwide study
    Springer Science and Business Media LLC ; 2022
    In:  BMC Cardiovascular Disorders Vol. 22, No. 1 ( 2022-12)
    Details
    In: BMC Cardiovascular Disorders, Springer Science and Business Media LLC, Vol. 22, No. 1 ( 2022-12)
    Abstract: Valve surgery guidelines for infective endocarditis (IE) are unchanged over decades and nationwide data about the use of valve surgery do not exist. Methods We included patients with first-time IE (1999–2018) using Danish nationwide registries. Proportions of valve surgery were reported for calendar periods (1999–2003, 2004–2008, 2009–2013, 2014–2018). Comparing calendar periods in multivariable analyses, we computed likelihoods of valve surgery with logistic regression and rates of 30 day postoperative mortality with Cox regression. Results We included 8804 patients with first-time IE; 1981 (22.5%) underwent surgery during admission, decreasing by calendar periods ( N  = 360 [24.4%], N  = 483 [24.0%], N  = 553 [23.5%], N  = 585 [19.7%], P  =  〈  0.001 for trend). For patients undergoing valve surgery, median age increased from 59.7 to 66.9 years ( P  ≤ 0.001) and the proportion of males increased from 67.8% to 72.6% ( P  = 0.008) from 1999–2003 to 2014–2018. Compared with 1999–2003, associated likelihoods of valve surgery were: Odds ratio (OR) = 1.14 (95% CI: 0.96–1.35), OR = 1.20 (95% CI: 1.02–1.42), and OR = 1.10 (95% CI: 0.93–1.29) in 2004–2008, 2009–2013, and 2014–2018, respectively. 30 day postoperative mortalities were: 12.7%, 12.8%, 6.9%, and 9.7% by calendar periods. Compared with 1999–2003, associated mortality rates were: Hazard ratio (HR) = 0.96 (95% CI: 0.65–1.41), HR = 0.43 (95% CI: 0.28–0.67), and HR = 0.55 (95% CI 0.37–0.83) in 2004–2008, 2009–2013, and 2014–2018, respectively. Conclusions On a nationwide scale, 22.5% of patients with IE underwent valve surgery. Patient characteristics changed considerably and use of valve surgery decreased over time. The adjusted likelihood of valve surgery was similar between calendar periods with a trend towards an increase while rates of 30 day postoperative mortality decreased.
    Type of Medium: Online Resource
    ISSN: 1471-2261
    URL: Article
    DOI: 10.1186/s12872-022-02761-z
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 2059859-2
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  • 2
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    Long-term outcome after coronary endarterectomy adjunct to coronary artery bypass grafting
    Oxford University Press (OUP) ; 2019
    In:  Interactive CardioVascular and Thoracic Surgery Vol. 29, No. 1 ( 2019-07-01), p. 22-27
    Details
    In: Interactive CardioVascular and Thoracic Surgery, Oxford University Press (OUP), Vol. 29, No. 1 ( 2019-07-01), p. 22-27
    Type of Medium: Online Resource
    ISSN: 1569-9285
    URL: Article
    DOI: 10.1093/icvts/ivy363
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2019
    detail.hit.zdb_id: 2096257-5
    detail.hit.zdb_id: 3167862-2
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  • 3
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    “Shared accountability”: Experiences of employees in a servant leadership organization guided by growth
    Institute of Business Research ; 2023
    In:  Tímarit um viðskipti og efnahagsmál Vol. 20, No. 2 ( 2023-12-19), p. 155-172
    Details
    In: Tímarit um viðskipti og efnahagsmál, Institute of Business Research, Vol. 20, No. 2 ( 2023-12-19), p. 155-172
    Abstract: Despite the fact that many organizations attribute their success to the practice of servant leadership, only a few studies have been conducted to understand the experience of employees working for a devoted servant leadership organization. Thus, the aim of this study was to explore the lived experience of employees who work in an organization that has been committed to the practice of servant leadership for decades. To respond to the research question: What is it like for employees to work in a dedicated employee-owned servant leadership organization in the construction industry and facilities services business, 16 interviews were conducted, including six follow-up interviews. Half of the interviewees held management positions and the other half held non-management positions, and they had worked for the organization from two years to 50 years. The organization operates in the United States of America and offers services from engineering and construction to operations and maintenance. The interviews were analyzed and interpreted according to phenomenological methodology. Three themes emerged: “Not just the work life but your whole self,” “The sky is the limit”: Continuous growth of employees and the organization, and “Diverse minds make better decisions.” The findings demonstrate that the employees are dedicated to a balanced growth of the organization and its employees as they experience the practice of servant leadership as a holistic way to continually help each other to develop and grow the business, by building on shared accountability leading to employee satisfaction and positive organizational performance. The findings indicate that dedication to the continuous and balanced growth of the organization and its employees is the foundation of the practice of servant leadership.
    Type of Medium: Online Resource
    ISSN: 1670-4851 , 1670-4444
    URL: Article
    DOI: 10.24122/tve.a.2023.20.2.9
    Language: Unknown
    Publisher: Institute of Business Research
    Publication Date: 2023
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  • 4
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    Clinical Presentation of Native Mitral Valve Infective Endocarditis Determines Long-Term Outcome after Surgery : ISOLATED MITRAL VALVE ENDOCARDITIS
    Hindawi Limited ; 2015
    In:  Journal of Cardiac Surgery Vol. 30, No. 9 ( 2015-09), p. 669-676
    Details
    In: Journal of Cardiac Surgery, Hindawi Limited, Vol. 30, No. 9 ( 2015-09), p. 669-676
    Type of Medium: Online Resource
    ISSN: 0886-0440
    URL: Article
    DOI: 10.1111/jocs.12591
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2015
    detail.hit.zdb_id: 2108425-7
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  • 5
    Online Resource
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    Five-year survival after post-cardiotomy veno-arterial extracorporeal membrane oxygenation
    Oxford University Press (OUP) ; 2021
    In:  European Heart Journal. Acute Cardiovascular Care Vol. 10, No. 6 ( 2021-08-24), p. 595-601
    Details
    In: European Heart Journal. Acute Cardiovascular Care, Oxford University Press (OUP), Vol. 10, No. 6 ( 2021-08-24), p. 595-601
    Abstract: Veno-arterial (VA) extracorporeal membrane oxygenation (ECMO) support for post-cardiotomy cardiogenic shock (PCS) after adult cardiac surgery is associated with satisfactory hospital survival. However, data on long-term survival of these critically ill patients are scarce. Methods and results Between January 2010 and March 2018, 665 consecutive patients received VA-ECMO for PCS at 17 cardiac surgery centres and herein we evaluated their 5-year survival. The mean follow-up of this cohort was 1.7 ± 2.7 years (for hospital survivors, 4.6 ± 2.5 years). In this cohort, 240 (36.1%) patients survived to hospital discharge. Five-year survival of all patients was 27.7%. The PC-ECMO score was predictive of 5-year survival in these patients (0 point, 50.9%; 1 point, 44.9%; 2 points, 40.0%; 3 points, 34.7%; 4 points, 21.0%; 5 points, 17.6%; ≥6 points, 10.7%; P  & lt; 0.0001). Age was among factors independently associated with late survival, patients & gt;70 years old having a remarkably poor 5-year survival ( & lt;60 years: 39.2%; 60–69 years: 29.9%; 70–79 years: 12.3%; ≥80 years: 13.0%, P  & lt; 0.0001). Implantation of a ventricular assist device or heart transplant was performed in 3.2% of patients and their 5-year survival was 42.9% (for heart transplant, 63.6%). Conclusion  Veno-arterial extracorporeal membrane oxygenation for PCS is associated with satisfactory 5-year survival in young patients without critical pre-ECMO conditions. The use of VA-ECMO for PCS in patients & gt;70 years should be considered only after a judicious scrutiny of patient’s life expectancy. Future studies should evaluate whether satisfactory mid-term survival of these patients translates into a good functional outcome. Trial registration Clinicaltrials.gov—NCT03508505.
    Type of Medium: Online Resource
    ISSN: 2048-8726 , 2048-8734
    URL: Article
    DOI: 10.1093/ehjacc/zuaa039
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2021
    detail.hit.zdb_id: 2663340-1
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  • 6
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    Central versus Peripheral Postcardiotomy Veno-Arterial Extracorporeal Membrane Oxygenation: Systematic Review and Individual Patient Data Meta-Analysis
    MDPI AG ; 2022
    In:  Journal of Clinical Medicine Vol. 11, No. 24 ( 2022-12-14), p. 7406-
    Details
    In: Journal of Clinical Medicine, MDPI AG, Vol. 11, No. 24 ( 2022-12-14), p. 7406-
    Abstract: Background: It is unclear whether peripheral arterial cannulation is superior to central arterial cannulation for postcardiotomy veno-arterial extracorporeal membrane oxygenation (VA-ECMO). Methods: A systematic review was conducted using PubMed, Scopus, and Google Scholar to identify studies on postcardiotomy VA-ECMO for the present individual patient data (IPD) meta-analysis. Analysis was performed according to the intention-to-treat principle. Results: The investigators of 10 studies agreed to participate in the present IPD meta-analysis. Overall, 1269 patients were included in the analysis. Crude rates of in-hospital mortality after central versus peripheral arterial cannulation for VA-ECMO were 70.7% vs. 63.7%, respectively (adjusted OR 1.38, 95% CI 1.08–1.75). Propensity score matching yielded 538 pairs of patients with balanced baseline characteristics and operative variables. Among these matched cohorts, central arterial cannulation VA-ECMO was associated with significantly higher in-hospital mortality compared to peripheral arterial cannulation VA-ECMO (64.5% vs. 70.8%, p = 0.027). These findings were confirmed by aggregate data meta-analysis, which showed that central arterial cannulation was associated with an increased risk of in-hospital mortality compared to peripheral arterial cannulation (OR 1.35, 95% CI 1.04–1.76, I2 21%). Conclusions: Among patients requiring postcardiotomy VA-ECMO, central arterial cannulation was associated with an increased risk of in-hospital mortality compared to peripheral arterial cannulation. This increased risk is of limited magnitude, and further studies are needed to confirm the present findings and to identify the mechanisms underlying the potential beneficial effects of peripheral VA-ECMO.
    Type of Medium: Online Resource
    ISSN: 2077-0383
    URL: Article
    DOI: 10.3390/jcm11247406
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2662592-1
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  • 7
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    Comparing right- and left sided injection-drug related infective endocarditis
    Springer Science and Business Media LLC ; 2021
    In:  Scientific Reports Vol. 11, No. 1 ( 2021-01-13)
    Details
    In: Scientific Reports, Springer Science and Business Media LLC, Vol. 11, No. 1 ( 2021-01-13)
    Abstract: The aim of the study was to compare background characteristics, microbiology and outcome of patients with right-sided and left-sided intravenous drug use (IDU) associated infective endocarditis (IE). A nationwide retrospective study using the Swedish Registry on Infective Endocarditis between 2008 and 2019 was conducted. A total of 586 people with IDU-IE were identified and divided into left-sided (n = 204) and right-sided (n = 382) IE. Descriptive statistics, Cox-regression and Kaplan–Meier survival estimates were used. The mean age of patients in the left-sided group was 46 years compared to 35 years in the right-sided group, p  〈  0.001. Left-sided IE had a higher proportion of females. Staphylococcus aureus was the causative pathogen in 48% of cases in the left-sided group compared to 88% in the right-sided group. Unadjusted and adjusted long-term survival was better in right-sided IE compared to left-sided IE. Independent predictors of long-term mortality were increasing age, end-stage renal disease, nosocomial infection, brain emboli and left-sided IE. Left-sided IE was common in people with IDU but the proportion of females with left-sided IE was low. S. aureus was twice as common in right-sided IE compared to left-sided IE, and the long-term prognosis of right sided IDU-associated IE was better compared to left-sided IE despite the fact that few were operated.
    Type of Medium: Online Resource
    ISSN: 2045-2322
    URL: Article
    DOI: 10.1038/s41598-020-80869-y
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
    detail.hit.zdb_id: 2615211-3
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  • 8
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    Online Resource
    Late survival and heart failure after transcatheter aortic valve implantation
    SAGE Publications ; 2016
    In:  Asian Cardiovascular and Thoracic Annals Vol. 24, No. 4 ( 2016-05), p. 318-325
    Details
    In: Asian Cardiovascular and Thoracic Annals, SAGE Publications, Vol. 24, No. 4 ( 2016-05), p. 318-325
    Abstract: Short-term survival in patients undergoing transcatheter aortic valve implantation is favorable. Our aim was to evaluate late survival and composite clinical endpoints specified by the Valve Academic Research Consortium-2, including rehospitalization for congestive heart failure. Methods Between January 2008 and April 2014, 166 consecutive patients with severe symptomatic aortic stenosis underwent 168 transcatheter aortic valve implantation procedures at our facility. This cohort was compared with propensity score-matched aortic valve replacement patients. Event rates were estimated by the Kaplan-Meier method and compared using the log-rank test. Cox regression analysis was performed to determine predictors of outcome. Results Although 30-day mortality rates following both procedures were similar (4.2% and 4.8%; p = 0.81), significant differences were seen in corresponding rates of survival (51.7% ± 5.8% vs. 72.3% ± 4.3%; p  〈  0.001) and cumulative rehospitalization for congestive heart failure (41.3% ± 7.2% vs. 23% ± 4.3%; p = 0.006). New York Heart Association functional class IV preoperative status was an independent risk factor for rehospitalization due to congestive heart failure ( p = 0.015). Conclusions This study confirms the merit of transcatheter aortic valve implantation in high-risk patients with aortic stenosis, although late survival proved inferior to that of aortic valve replacement in propensity score-matched subjects. Early safety was excellent for both treatment groups, however, patients undergoing transcatheter aortic valve implantation had a higher incidence of rehospitalization for congestive heart failure and myocardial infarction during follow-up. Patients with severe congestive heart failure should be carefully monitored and aggressively treated to improve outcomes.
    Type of Medium: Online Resource
    ISSN: 0218-4923 , 1816-5370
    URL: Article
    DOI: 10.1177/0218492316637712
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 2044527-1
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  • 9
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    Guidelines for co-creating climate adaptation plans for fisheries and aquaculture
    Springer Science and Business Media LLC ; 2021
    In:  Climatic Change Vol. 164, No. 3-4 ( 2021-02)
    Details
    In: Climatic Change, Springer Science and Business Media LLC, Vol. 164, No. 3-4 ( 2021-02)
    Abstract: Climate change is having a significant impact on the biology and ecology of fish stocks and aquaculture species and will affect the productivity within seafood supply chains in the future. The challenges are further amplified when actors within the fisheries and aquaculture sectors have very different ideas and assumptions about climate change and what risks and opportunities they entail. In order to address the challenges of climate change, several countries have developed national adaptation plans. However, fisheries and aquaculture are rarely included in these plans, resulting in a general lack of documented adaptation strategies within these sectors in most countries. This paper introduces guidelines for the development of climate adaptation plans (CAPs) within fisheries and aquaculture, applying a co-creation approach that requires the participation of scientists, industry representatives, policymakers, and other relevant stakeholders. The objective is to provide a stepwise approach to facilitate and enable stakeholders to plan strategies toward climate adaptation. The guidelines are based on practical experience and include a three-step process: (1) assessment of risks and opportunities; (2) identification of adaptation measures, and (3) operationalization of CAPs. The three-step process is also part of a larger cycle, including implementation, monitoring, and evaluation, again generating iterative feedback loops over time. Lessons learned are discussed, and we highlight the advantages and challenges of developing CAPs. While the guidelines are designed for and tested within fisheries and aquaculture systems, the CAP approach is also employable for other natural resource-based systems.
    Type of Medium: Online Resource
    ISSN: 0165-0009 , 1573-1480
    URL: Article
    DOI: 10.1007/s10584-021-03041-z
    RVK:
    RA 1000
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
    detail.hit.zdb_id: 751086-X
    detail.hit.zdb_id: 1477652-2
    SSG: 14
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  • 10
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    Late right ventricular performance after mitral valve repair assessed by exercise echocardiography
    Springer Science and Business Media LLC ; 2018
    In:  General Thoracic and Cardiovascular Surgery Vol. 66, No. 7 ( 2018-7), p. 398-404
    Details
    In: General Thoracic and Cardiovascular Surgery, Springer Science and Business Media LLC, Vol. 66, No. 7 ( 2018-7), p. 398-404
    Type of Medium: Online Resource
    ISSN: 1863-6705 , 1863-6713
    URL: Article
    DOI: 10.1007/s11748-018-0918-x
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2018
    detail.hit.zdb_id: 2268248-X
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