In:
PLOS Computational Biology, Public Library of Science (PLoS), Vol. 19, No. 2 ( 2023-2-9), p. e1010899-
Abstract:
Paramecium is a large unicellular organism that swims in fresh water using cilia. When stimulated by various means (mechanically, chemically, optically, thermally), it often swims backward then turns and swims forward again in a new direction: this is called the avoiding reaction. This reaction is triggered by a calcium-based action potential. For this reason, several authors have called Paramecium the “swimming neuron”. Here we present an empirically constrained model of its action potential based on electrophysiology experiments on live immobilized paramecia, together with simultaneous measurement of ciliary beating using particle image velocimetry. Using these measurements and additional behavioral measurements of free swimming, we extend the electrophysiological model by coupling calcium concentration to kinematic parameters, turning it into a swimming model. In this way, we obtain a model of autonomously behaving Paramecium . Finally, we demonstrate how the modeled organism interacts with an environment, can follow gradients and display collective behavior. This work provides a modeling basis for investigating the physiological basis of autonomous behavior of Paramecium in ecological environments.
Type of Medium:
Online Resource
ISSN:
1553-7358
DOI:
10.1371/journal.pcbi.1010899
DOI:
10.1371/journal.pcbi.1010899.g001
DOI:
10.1371/journal.pcbi.1010899.g002
DOI:
10.1371/journal.pcbi.1010899.g003
DOI:
10.1371/journal.pcbi.1010899.g004
DOI:
10.1371/journal.pcbi.1010899.g005
DOI:
10.1371/journal.pcbi.1010899.g006
DOI:
10.1371/journal.pcbi.1010899.g007
DOI:
10.1371/journal.pcbi.1010899.g008
DOI:
10.1371/journal.pcbi.1010899.g009
DOI:
10.1371/journal.pcbi.1010899.g010
DOI:
10.1371/journal.pcbi.1010899.g011
DOI:
10.1371/journal.pcbi.1010899.g012
DOI:
10.1371/journal.pcbi.1010899.t001
DOI:
10.1371/journal.pcbi.1010899.t002
DOI:
10.1371/journal.pcbi.1010899.t003
DOI:
10.1371/journal.pcbi.1010899.s001
DOI:
10.1371/journal.pcbi.1010899.s002
DOI:
10.1371/journal.pcbi.1010899.s003
DOI:
10.1371/journal.pcbi.1010899.s004
DOI:
10.1371/journal.pcbi.1010899.s005
DOI:
10.1371/journal.pcbi.1010899.s006
DOI:
10.1371/journal.pcbi.1010899.s007
DOI:
10.1371/journal.pcbi.1010899.s008
DOI:
10.1371/journal.pcbi.1010899.s009
DOI:
10.1371/journal.pcbi.1010899.s010
DOI:
10.1371/journal.pcbi.1010899.r001
DOI:
10.1371/journal.pcbi.1010899.r002
DOI:
10.1371/journal.pcbi.1010899.r003
DOI:
10.1371/journal.pcbi.1010899.r004
DOI:
10.1371/journal.pcbi.1010899.r005
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2023
detail.hit.zdb_id:
2193340-6
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