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  • 1
    Online Resource
    Online Resource
    Experimental and model validation of photovoltaic-thermal (PVT) air collector: exergy analysis
    National Research and Innovation Agency ; 2021
    In:  Journal of Mechatronics, Electrical Power, and Vehicular Technology Vol. 12, No. 1 ( 2021-07-31), p. 10-17
    Details
    In: Journal of Mechatronics, Electrical Power, and Vehicular Technology, National Research and Innovation Agency, Vol. 12, No. 1 ( 2021-07-31), p. 10-17
    Abstract: Solar energy is a renewable energy that can produce heat via a thermal system and generate electricity via a photovoltaic (PV) module. A photovoltaic-thermal (PVT) collector is a system that has a PV module combined with a thermal collector system. The PVT collector is a popular technology for harvesting solar energy. A PVT collector can generate both electrical and thermal energies simultaneously. The study aims to validate the PV and outlet temperature for various mass flow rates and solar radiation. To develop a predictive model, a steady-state energy analysis of a PVT air collector was performed. An energy balance equation was solved using the matrix inversion method. The theoretical model was developed and validated against the experimental results, which have a similar trend and are consistent with the experimental results. On the other hand, the validated model was used to study the performances of PVT air collectors using exergy analysis for the mass flow rate ranging from 0.007 kg/s to 0.07 kg/s and solar radiation ranging from 385 W/m2 to 820 W/m2. The result from the mathematical model was found to be consistent with the experimental data with an accuracy of about 95 %. The average PVT exergy efficiency was found to be 12.7 % and 12.0 % for the theoretical and experimental studies, respectively.
    Type of Medium: Online Resource
    ISSN: 2088-6985 , 2087-3379
    URL: Article
    DOI: 10.14203/j.mev.2021.v12.10-17
    Language: Unknown
    Publisher: National Research and Innovation Agency
    Publication Date: 2021
    detail.hit.zdb_id: 2823604-X
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  • 2
    Online Resource
    Online Resource
    Mapping the human genetic architecture of COVID-19
    Springer Science and Business Media LLC ; 2021
    In:  Nature Vol. 600, No. 7889 ( 2021-12-16), p. 472-477
    Details
    In: Nature, Springer Science and Business Media LLC, Vol. 600, No. 7889 ( 2021-12-16), p. 472-477
    Abstract: The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity of COVID-19 1,2 , host genetics may also be important. Identifying host-specific genetic factors may reveal biological mechanisms of therapeutic relevance and clarify causal relationships of modifiable environmental risk factors for SARS-CoV-2 infection and outcomes. We formed a global network of researchers to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity. Here we describe the results of three genome-wide association meta-analyses that consist of up to 49,562 patients with COVID-19 from 46 studies across 19 countries. We report 13 genome-wide significant loci that are associated with SARS-CoV-2 infection or severe manifestations of COVID-19. Several of these loci correspond to previously documented associations to lung or autoimmune and inflammatory diseases 3–7 . They also represent potentially actionable mechanisms in response to infection. Mendelian randomization analyses support a causal role for smoking and body-mass index for severe COVID-19 although not for type II diabetes. The identification of novel host genetic factors associated with COVID-19 was made possible by the community of human genetics researchers coming together to prioritize the sharing of data, results, resources and analytical frameworks. This working model of international collaboration underscores what is possible for future genetic discoveries in emerging pandemics, or indeed for any complex human disease.
    Type of Medium: Online Resource
    ISSN: 0028-0836 , 1476-4687
    URL: Article
    DOI: 10.1038/s41586-021-03767-x
    RVK:
    TA 1000
    RVK:
    UA 1000
    RVK:
    WA 15000
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
    detail.hit.zdb_id: 120714-3
    detail.hit.zdb_id: 1413423-8
    SSG: 11
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  • 3
    Online Resource
    Online Resource
    Amino Acid Profiles of Coffee Cherry Flour from Different Origins: A Comparative Approach
    EDP Sciences ; 2023
    In:  E3S Web of Conferences Vol. 432 ( 2023), p. 00032-
    Details
    In: E3S Web of Conferences, EDP Sciences, Vol. 432 ( 2023), p. 00032-
    Abstract: A popular beverage globally attributable to its energizing properties and distinctive flavor, coffee is one of the majorly produced agricultural merchandise. With the reputation, nonetheless, comes a sizeable waste in its production process. Reduce, reuse, recycle, and improve circular economy —coffee pulp and husk waste into functional food, i.e ., coffee cherry flour. This study examined the amino acid composition and contents originating from four locations: Ijen Farm, Karang Ploso Farm, Mengani Farm, and La Boitê. In triplication, samples were filtrated, derivated, and analyzed through high-performance liquid chromatography with fluorescence detection. The obtained data were then computed to determine the amino acid retention times and peak areas to facilitate the quantification of amino acid concentrations within the samples. ANOVA was involved in evaluating the significance of amino acid level variations, and then nonparametric correlation and cluster tests were conducted for a dendrogram presentation. The result stated that Serine, Histidine, Threonine, Alanine, Cysteine, Methionine, and Isoleucine are positively correlated to the area characteristics, while Aspartic acid, Glutamic acid, Glycine, Arginine, Proline, Tyrosine, Valine, Lysine, Leucine, and Phenylalanine are of negative association. This finding suggests that locally-grown coffee cherry flour should be feasible for functional food beneficial to health.
    Type of Medium: Online Resource
    ISSN: 2267-1242
    URL: Article
    DOI: 10.1051/e3sconf/202343200032
    Language: English
    Publisher: EDP Sciences
    Publication Date: 2023
    detail.hit.zdb_id: 2755680-3
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  • 4
    Online Resource
    Online Resource
    Phytochemical, Antimicrobial, Antidiabetic, Thrombolytic, anticancer Activities, and in silico studies of Ficus palmata Forssk
    Elsevier BV ; 2023
    In:  Arabian Journal of Chemistry Vol. 16, No. 2 ( 2023-02), p. 104455-
    Details
    In: Arabian Journal of Chemistry, Elsevier BV, Vol. 16, No. 2 ( 2023-02), p. 104455-
    Type of Medium: Online Resource
    ISSN: 1878-5352
    URL: Article
    DOI: 10.1016/j.arabjc.2022.104455
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2023
    detail.hit.zdb_id: 2515214-2
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  • 5
    Online Resource
    Online Resource
    A comprehensive review on water pollution, South Asia Region: Pakistan
    Elsevier BV ; 2023
    In:  Urban Climate Vol. 48 ( 2023-03), p. 101413-
    Details
    In: Urban Climate, Elsevier BV, Vol. 48 ( 2023-03), p. 101413-
    Type of Medium: Online Resource
    ISSN: 2212-0955
    URL: Article
    DOI: 10.1016/j.uclim.2023.101413
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2023
    detail.hit.zdb_id: 2683732-8
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  • 6
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    Online Resource
    Phytochemical Profiling, In Vitro Biological Activities, and In-Silico Studies of Ficus vasta Forssk.: An Unexplored Plant
    MDPI AG ; 2022
    In:  Antibiotics Vol. 11, No. 9 ( 2022-08-26), p. 1155-
    Details
    In: Antibiotics, MDPI AG, Vol. 11, No. 9 ( 2022-08-26), p. 1155-
    Abstract: Ficus vasta Forssk. (Moraceae family) is an important medicinal plant that has not been previously investigated for its phytochemical and biological potential. Phytochemical screening, total bioactive content, and GCMS analysis were used to determine its phytoconstituents profile. Antioxidant, antibacterial, antifungal, anti-viral, cytotoxicity, thrombolytic, and enzyme inhibition activities were examined for biological evaluation. The plant extract exhibited the maximum total phenolic (89.47 ± 3.21 mg GAE/g) and total flavonoid contents (129.2 ± 4.14 mg QE/g), which may be related to the higher antioxidant potential of the extract. The extract showed strong α-amylase (IC50 5 ± 0.21 µg/mL) and α-glucosidase inhibition activity (IC50 5 ± 0.32 µg/mL). Significant results were observed in the case of antibacterial, antifungal, and anti-viral activities. The F. vasta extract inhibited the growth of HepG2 cells in a dose-dependent manner. The GCMS analysis of the extract provided the preliminary identification of 28 phytocompounds. In addition, the compounds identified by GCMS were subjected to in silico molecular docking analysis in order to identify any interactions between the compounds and enzymes (α-amylase and α-glucosidase). After that, the best-docked compounds were subjected to ADMET studies which provide information on pharmacokinetics, drug-likeness, physicochemical properties, and toxicity. The present study highlighted that the ethanol extract of F. vasta has antidiabetic, antimicrobial, anti-viral, and anti-cancer potentials that can be further explored for novel drug development.
    Type of Medium: Online Resource
    ISSN: 2079-6382
    URL: Article
    DOI: 10.3390/antibiotics11091155
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2681345-2
    SSG: 15,3
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  • 7
    Online Resource
    Online Resource
    Self-reported health and smoking status, and body mass index: a case-control comparison based on GEN SCRIP (GENetics of SChizophRenia In Pakistan) data
    BMJ ; 2021
    In:  BMJ Open Vol. 11, No. 4 ( 2021-04), p. e042331-
    Details
    In: BMJ Open, BMJ, Vol. 11, No. 4 ( 2021-04), p. e042331-
    Abstract: Individuals with schizophrenia are at a high risk of physical health comorbidities and premature mortality. Cardiovascular and metabolic causes are an important contributor. There are gaps in monitoring, documenting and managing these physical health comorbidities. Because of their condition, patients themselves may not be aware of these comorbidities and may not be able to follow a lifestyle that prevents and manages the complications. In many low-income and middle-income countries including Pakistan, the bulk of the burden of care for those struggling with schizophrenia falls on the families. Objectives To determine the rate of self-reported physical health disorders and risk factors, like body mass index (BMI) and smoking, associated with cardiovascular and metabolic disorders in cases of schizophrenia compared with a group of mentally healthy controls. Design A case-controlled, cross-sectional multicentre study of patients with schizophrenia in Pakistan. Settings Multiple data collection sites across the country for patients, that is, public and private psychiatric OPDs (out patient departments), specialised psychiatric care facilities, and psychiatric wards of teaching and district level hospitals. Healthy controls were enrolled from the community. Participants We report a total of 6838 participants’ data with (N 3411 (49.9%)) cases of schizophrenia compared with a group of healthy controls (N 3427 (50.1%)). Results BMI (OR 0.98 (CI 0.97 to 0.99), p=0.0025), and the rate of smoking is higher in patients with schizophrenia than in controls. Problems with vision (OR 0.13 (0.08 to 0.2), joint pain (OR 0.18 (0.07 to 0.44)) and high cholesterol (OR 0.13 (0.05 to 0.35)) have higher reported prevalence in controls. The cases describe more physical health disorders in the category ‘other’ (OR 4.65 (3.01 to 7.18)). This captures residual disorders not listed in the questionnaire. Conclusions Participants with schizophrenia in comparison with controls report more disorders. The access in the ‘other’ category may be a reflection of undiagnosed disorders.
    Type of Medium: Online Resource
    ISSN: 2044-6055 , 2044-6055
    URL: Article
    DOI: 10.1136/bmjopen-2020-042331
    Language: English
    Publisher: BMJ
    Publication Date: 2021
    detail.hit.zdb_id: 2599832-8
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  • 8
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    Online Resource
    Thermal Management of Microelectronic Devices Using Nanofluid with Metal foam Heat Sink
    MDPI AG ; 2023
    In:  Micromachines Vol. 14, No. 7 ( 2023-07-23), p. 1475-
    Details
    In: Micromachines, MDPI AG, Vol. 14, No. 7 ( 2023-07-23), p. 1475-
    Abstract: Microelectronic components are used in a variety of applications that range from processing units to smart devices. These components are prone to malfunctions at high temperatures exceeding 373 K in the form of heat dissipation. To resolve this issue, in microelectronic components, a cooling system is required. This issue can be better dealt with by using a combination of metal foam, heat sinks, and nanofluids. This study investigates the effect of using a rectangular-finned heat sink integrated with metal foam between the fins, and different water-based nanofluids as the working fluid for cooling purposes. A 3D numerical model of the metal foam with a BCC-unit cell structure is used. Various parameters are analyzed: temperature, pressure drop, overall heat transfer coefficient, Nusselt number, and flow rate. Fluid flows through the metal foam in a turbulent flow with a Reynold’s number ranging from 2100 to 6500. The optimum fin height, thickness, spacing, and base thickness for the heat sink are analyzed, and for the metal foam, the material, porosity, and pore density are investigated. In addition, the volume fraction, nanoparticle material, and flow rate for the nanofluid is obtained. The results showed that the use of metal foam enhanced the thermal performance of the heat sink, and nanofluids provided better thermal management than pure water. For both cases, a higher Nusselt number, overall heat transfer coefficient, and better temperature reduction is achieved. CuO nanofluid and high-porosity low-pore-density metal foam provided the optimum results, namely a base temperature of 314 K, compared to 341 K, with a pressure drop of 130 Pa. A trade-off was achieved between the temperature reduction and pumping power, as higher concentrations of nanofluid provided better thermal management and resulted in a large pressure drop.
    Type of Medium: Online Resource
    ISSN: 2072-666X
    URL: Article
    DOI: 10.3390/mi14071475
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2620864-7
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  • 9
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    Online Resource
    SHARIAH DECONSTRUCTION: THE THOUGHTS OF ABDULLAHI AHMED AN-NA'IM
    Universitas Islam Negeri Sultan Syarif Kasim Riau ; 2023
    In:  Hukum Islam Vol. 23, No. 1 ( 2023-08-02), p. 124-
    Details
    In: Hukum Islam, Universitas Islam Negeri Sultan Syarif Kasim Riau, Vol. 23, No. 1 ( 2023-08-02), p. 124-
    Abstract: Abdullahi Ahmed an-Na'im's Sharia Deconstruction is an alternative thought in sharia-based law reform. This thinking tries to reflect back on the dominant authority and interpretation in the Islamic legal tradition, by proposing an approach that is based on universal values such as fairness, fairness, and protection of human rights. An-Na'im argues that Islamic law must be seen as a social construction formed through a historical process and a particular context, and must be reconstructed in accordance with the demands of modern times. An-Na'im's sharia deconstruction approach also emphasizes the importance of freedom of religion and equality in society. He proposed peace between religion and the state, in which the state must treat neutrally and treat all citizens without taking sides or discriminating against certain religions. This thinking aims to create a legal system that is more inclusive and democratic, which involves the active participation of the community in determining appropriate laws and policies. Even though an-Na'im's deconstruction of sharia provides an alternative perspective in sharia-based legal reform, this view is still the subject of presumption among Islamic scholars and scholars. There are various viewpoints in interpreting and applying Islamic law, and the an-Na'im approach is only one of many existing approaches.
    Type of Medium: Online Resource
    ISSN: 2443-0609 , 1411-8041
    URL: Article
    DOI: 10.24014/jhi.v23i1.21123
    Language: Unknown
    Publisher: Universitas Islam Negeri Sultan Syarif Kasim Riau
    Publication Date: 2023
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  • 10
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    Online Resource
    The Impact of Orthodontic fixed appliance and clear plastic aligner in periodontal health; A comparative clinical study
    Lahore Medical and Dental College ; 2022
    In:  Pakistan Journal of Medical and Health Sciences Vol. 16, No. 4 ( 2022-04-26), p. 305-307
    Details
    In: Pakistan Journal of Medical and Health Sciences, Lahore Medical and Dental College, Vol. 16, No. 4 ( 2022-04-26), p. 305-307
    Abstract: Objective: To find out the periodontal health of patients with fixed orthodontic and clear aligner treatment with a follow-up of three months supportive periodontal therapy. Study Setting: After receiving approval from the hospital's ethical committee the study was conducted at Department of Dentistry Faryal Dental College, Sheikhupura from September 2021 to February 2022. Material and Methods: For this study 40 individuals were selected and divided them into 2 different groups regarding age and mode of treatment. In Group E, 20 individuals were of age in between 15-30 years and they used multi-bracket fixed therapy while in Group F, 20 individuals of age in between 15- 30 years were used treatment with clear aligners. Results: Results of current study were significant (P 〈 0.05) regarding logistic regression model of descriptive statistics of dependent variables measured for periodontal therapy after 3 month follow-up respectively. Percentage standard mean deviation (Mean±SD) levels of recovery rate, patient compliance, probing depth, plaque index, bleeding on probing and gingival recession for fixed appliance brackets and clear aligners were (56.21± 11.11, 31.14± 11.11, 13.04± 10.01, 26.10± 3.10, 15.21± 10.12, 01.12± 13.11),( 59.22± 1.01, 43.11± 01.10, 14.01± 11.21, 22.10± 3.10, 6.11± 10.11, 06.12± 14.11) noted respectively. Conclusion: The results of current study were significant (P 〈 0.05) regarding logistic regression model of descriptive statistics of dependent variables measured for periodontal therapy after 3 month follow-up respectively. Patient compliance with clear aligner treatment was higher than fixed appliance brackets. Key words: Fixed orthodontic appliance, clear aligner, periodontal diseases
    Type of Medium: Online Resource
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.53350/pjmhs22164
    DOI: 10.53350/pjmhs2216
    DOI: 10.53350/pjmhs22164305
    Language: Unknown
    Publisher: Lahore Medical and Dental College
    Publication Date: 2022
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