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  • 11
    Electronic Resource
    Electronic Resource
    350 Main Street , Malden , MA 02148-5018 , USA , and 9600 Garsington Road , Oxford OX4 2DQ , UK . : Blackwell Science Inc
    Journal of cardiovascular electrophysiology 16 (2005), S. 0 
    ISSN: 1540-8167
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Introduction: Cryocatheter techniques have been successfully applied to treat supraventricular tachycardia but there are no reports on their value in treating ventricular tachycardia (VT). We present our initial experience with cryocatheter ablation of right ventricular outflow tract (RVOT) tachycardia. Methods and Results: Cryocatheter ablation was attempted in 14 patients (13 females, age 45.9 ± 12.7 years) who were highly symptomatic due to frequent monomorphic ventricular extrasystole (VES) or nonsustained VT originating within the RVOT. A 9-Fr, 8-mm-tip cryocatheter was used for both mapping and ablation. Cryoablation was started after localizing the arrhythmic focus by pace and activation mapping. Ablation success, defined by complete disappearance of target VES/VT acutely and during a follow-up of 9.3 ± 1.4 weeks, was achieved in 13 of 14 patients. Ablation was successful with local activation times of 35 ± 4 ms, 5.8 ± 3.3 applications, 18.8 ± 7.5 minutes total cryo time, 9.4 ± 4.2 minutes fluoroscopy time, and 66.9 ± 26.1 minutes total procedure time, the latter two measures showing a reduction with number of patients treated. Three patients reported slight pain related to local pressure of the catheter on the RVOT wall. No pain was described related to delivery of cryothermal energy. Conclusions: Initial experience shows that focal VES/VT originating in the RVOT can be successfully treated using cryocatheter ablation. Acute and short term success rates, fluoroscopy times, and duration of procedure are comparable to conventional ablation techniques. A major advantage seems to be the virtual absence of ablation related pain.
    Type of Medium: Electronic Resource
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  • 12
    ISSN: 1572-8595
    Keywords: linear lesions ; catheter ablation ; pulsed energy delivery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: For invasive treatment of atrial fibrillation, linear lesions induced with multipolar ablation catheters (MAC) are needed to prevent recurrence. The aim of the study was to compare the efficacy of pulsed versus continuous radiofrequency (RF)-energy delivery using MAC. Methods: In vitro tests were performed using endomyocardial preparations of fresh pig hearts in a 10-liter-bath of physiologic saline solution (37°C) at constant flow conditions (1.5[emsp4 ]l/min). The MAC were placed with a constant pressure of 20 ponds onto the endocardium. The energy (generator: Osypka HAT 200 S) was delivered either pulsed (4 electrodes simultaneously, 5[emsp4 ]ms duty-cycle) or continuously (each electrode separately). In vivo experiments were performed in 6 anesthetized pigs using fluoroscopic positioning of MAC at 40 different intracardial positions and with similar conditions as in vitro experiments. Lesion volume (LV) was calculated after measuring lesion diameter with a microcaliper. The homogeneity of the lesions (LH) was classified from 1–4; with 1 as highest homogeneity. Results: Pulsed energy delivery produced more homogeneous linear lesions in significantly less time. There was no difference in electrode temperature values (50.2±0.8 and 51.3±1.4°C) in vitro and in vivo. In the in vivo experiments, lesion depth and calculated lesion volume were less in both modes of energy delivery but pulsed energy delivery was superior regarding lesion depth and homogeneity. Conclusion: With pulsed energy delivery it is possible to create linear lesions of significantly greater homogeneity. Moreover, larger lesions are induced in less time by pulsed energy delivery in vitro and in vivo.
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  • 13
    ISSN: 1615-6722
    Keywords: Schlüsselwörter Synkope ; Diagnostik ; “Loop”-Recorder ; Key Words Syncope ; Diagnosis ; Loop recorder
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract Background: In about a third of cases of recurrent syncope a diagnosis cannot be established despite extensive cardiovascular and neurologic testing. In patients without underlying heart disease the sensitivity of conventional diagnostic testing is low. Case Report: A 33-year-old male patient underwent implantation of a loop recorder (Reveal®) after negative neurological and cardiovascular testing. One month after implantation sinus node arrest could be documented during a presyncope. The patient underwent pacemaker implantation and remains asymptomatic since then. Conclusion: In patients with syncope and a negative conventional diagnostic workup the implantable loop recorder is a helpful and cost-effective diagnostic tool.
    Notes: Zusammenfassung Hintergrund: Die Diagnostik rezidivierender Synkopen bleibt trotz neurologischer und invasiver kardiologischer Befunderhebung in etwa einem Drittel der Fälle ohne Ergebnis. Insbesondere bei Patienten ohne kardiale Grundkrankheit und ohne Hinweise auf ein Anfallsleiden sind konventionelle diagnostische Methoden wenig sensitiv. Falldarstellung: Einem 33jährigen Patienten mit rezidivierenden Synkopen und umfangreicher negativer neurologischer und kardiologischer Diagnostik wurde ein “Loop”:-Recorder (Reveal®) implantiert. Bereits einen Monat nach Implantation konnte im Rahmen einer Präsynkope ein Sinusarrest mit 3,7 Sekunden Pause aufgezeichnet werden. Daraufhin wurde die Indikation zur Schrittmacherimplantation gestellt, und der Patient ist seitdem symptomfrei. Schlußfolgerung: Bei negativer Synkopendiagnostik stellt der implantierte “Loop”-Recorder eine wertvolle und kosteneffektive Untersuchungsmethode dar.
    Type of Medium: Electronic Resource
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