ISSN:
1432-1076
Keywords:
Malignant infantile osteopetrosis
;
Calcitriol
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract In an attempt to stimulate bone resportion, a 10-week-old infant with malignant infantile osteopetrosis was treated with high doses of calcitriol, a potent bone resorption stimulatory agent, combined with a low calcium diet to prevent hypercalcaemia. Although calcitriol administration was initiated at this very young age, our patient did not show any clinical, radiological, or histological improvement. Despite reports of positive results of this treatment in the literature, our patient did not reveal any signs of bone resorption. She eventually died from the complications of osteopetrosis at the age of 6 months after 88 days of therapy.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02073378
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