GLORIA

GEOMAR Library Ocean Research Information Access

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Online Resource
    Online Resource
    The Lords of Lambityeco : Political Evolution in the Valley of Oaxaca during the Xoo Phase (2009)
    Boulder : University Press of Colorado
    Details Availability
    Keywords: Lambityeco Site (Mexico) ; Excavations (Archaeology) ; Mexico ; Lambityeco Site ; Lambityeco Site (Mexico) ; Oaxaca Valley (Mexico) ; Antiquities ; Social archaeology ; Mexico ; Oaxaca Valley ; Zapotec Indians ; Antiquities ; Zapotec Indians ; Politics and government ; Electronic books
    Description / Table of Contents: Intro -- Contents -- Figures -- Tables -- Foreword -- Preface -- 1: Introduction -- 2: Lambityeco in the Valley of Oaxaca -- 3: Lambityeco: The Economic Basis -- 4: Site Structure and Community Organization -- 5: Excavations in Mound 195 Sub -- 6: Structure 195-3 -- 7: Tomb 6 -- 8: The Houses of Tomb 3 and Tomb 4 -- 9: Mound 195 -- 10: Political Evolution during the Xoo Phase and the Collapse of Monte Albán -- Appendix 1: Calibrated Radiocarbon Dates for the Late Classic and Postclassic Periods in the Valley of Oaxaca, Mexico -- Appendix 2: The Lambityeco Mounds -- References -- Index.
    Type of Medium: Online Resource
    Pages: 1 online resource (441 pages)
    ISBN: 9781607320425
    Series Statement: Mesoamerican Worlds
    URL: https://ebookcentral.proquest.com/lib/kxp/detail.action?docID=3039716
    DDC: 972/.74
    Language: English
    Note: Description based on publisher supplied metadata and other sources
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    GEOMAR CATALOGUE
    Link to Library Catalog
    get availability status
  • 2
    Electronic Resource
    Electronic Resource
    Pharmacokinetics of carboplatin administered in combination with the bradykinin agonist Cereport (RMP-7) for the treatment of brain tumours (2000)
    Springer
    Cancer chemotherapy and pharmacology 45 (2000), S. 284-290 
    Details
    ISSN: 1432-0843
    Keywords: Key words Carboplatin ; Pharmacokinetics ; Cereport ; Clinical ; Brain tumour
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Introduction: Cereport (RMP-7) is a novel bradykinin agonist which is being developed as a modulator of the blood–brain barrier (BBB). In order to investigate the pharmacokinetics of carboplatin in combination with Cereport, we performed pharmacological studies in conjunction with early clinical trials. Methods: Pharmacokinetic samples were collected from eight patients in a phase I study (Cereport 100–300 ng/kg) and ten patients in a phase II study (Cereport 300 ng/kg). Pharmacokinetic parameters for carboplatin were compared with respect to the dose of Cereport and with historical controls. Results: Cereport combined with carboplatin was well-tolerated, with mild haematological toxicities consistent with the target area under the concentration–time curve (AUC) of 7 mg/ml*min. Although the clearance of carboplatin was within the range reported for this drug alone, the addition of Cereport resulted in a higher than expected carboplatin AUC. This effect was related to the dose of Cereport in the phase I study (AUC values 104–133% of target, Spearman rank correlation coefficient=0.71, P 〈 0.001). The higher than expected AUC value was confirmed in the phase II study (AUC values 106–189% of target). Conclusions: Co-administration of Cereport with carboplatin may result in a greater than predicted AUC. The mechanism of this possible interaction remains to be determined, although this did not result in any increased toxicity. Thus, the clinical potential of this combination in the treatment of brain tumours warrants further investigation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002800050042
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...