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  • 1
    Electronic Resource
    Electronic Resource
    Use of hyperbaric oxygen chamber in the management of radiation-related complications of the anorectal region (2000)
    Springer
    Diseases of the colon & rectum 43 (2000), S. 1435-1438 
    Details
    ISSN: 1530-0358
    Keywords: Hyperbaric oxygen treatment ; Radiation damage in anorectal region
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract PURPOSE: This article was undertaken to present two cases of nonhealing ulcers that occurred after primary radiation therapy and local excision of suspected residual or recurrent anal carcinomas. Both patients responded favorably to hyperbaric chamber treatment. Review of the literature is discussed, including cause, clinical presentation, diagnosis, and options for management of radiation-related complications in the anorectal region and use of hyperbaric oxygen treatment in colorectal surgery. METHODS: The cases of two patients with recurrent or residual anal carcinomas were reviewed. Objective clinical, laboratory test, and intraoperative findings were implemented to define this pathologic entity precisely, results of its treatment, and management of radiation-related complications. RESULTS: The study shows clinical effectiveness of hyperbaric chamber treatment for nonhealing wounds in the previously radiated anorectal region. The refractory wounds of both our patients healed. The patients were rendered free of symptoms. CONCLUSIONS: Substantial pathologic changes in the irradiated tissues leading occasionally to nonhealing radiation proctitis are relatively infrequent consequences of radiation therapy for pelvic malignancies. Excisional and incisional biopsies of the radiation-injured tissues result in chronic ulcers accompanied by debilitating symptoms. Hyperbaric chamber treatment seemed to be a very effective means of therapy of radiation proctitis and nonhealing wounds in the involved anorectal region after conventional therapy had failed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02236641
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  • 2
    Electronic Resource
    Electronic Resource
    X-ray photoelectron spectroscopy of boron implanted 4145 steel surface (1986)
    Springer
    Applied physics 40 (1986), S. 91-93 
    Details
    ISSN: 1432-0630
    Keywords: 68.25 ; 73.20
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract The near-surface region of 4145 steel following boron implantation was investigated by x-ray photoelectron spectroscopy (XPS). The steel surface was implanted with11B+ ions to a constant dose of 1.0×1017 ions cm−2 at energies of 30 and 135 keV. The XPS spectrum of the implanted surface showed a shift in the B(1s) level towards the higher binding energy. The observed 188.0 eV binding energy of the B(1s) level was found to be in good agreement with the characteristic binding energy of the B(1s) level corresponding to iron boride (Fe2B). Hence the increase in surface hardness reported previously is related to the formation of an iron boride layer in the near-surface region known for its hardening capabilities.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00616483
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  • 3
    Electronic Resource
    Electronic Resource
    Familial interruption of the aortic arch (1993)
    Springer
    Pediatric cardiology 14 (1993), S. 110-115 
    Details
    ISSN: 1432-1971
    Keywords: Interruption of the aortic arch ; Conotruncal malformations ; Familial cardiac anomaly
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Interruption of the aortic arch (IAA) is an important congenital cardiac malformation occurring in 1.4% of cases with a congenital cardiac malformation. Only two reports have described IAA in siblings, each with type B and an anomalous right subclavian artery. We report the occurrence of IAA type B with an anomalous right subclavian artery in two siblings and their half-sibling, each of whom had additional conotruncal cardiac malformations. Recent evidence suggests that conotruncal cardiac malformations, including IAA type B, are related to abnormalities of neural crest cell migration. Thus, the family reported herein may manifest a syndrome related to alterations in mesenchymal tissue/neural crest cell migration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00796990
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  • 4
    Electronic Resource
    Electronic Resource
    Intravenous KCl supplementation in pediatric cardiac surgical patients (1985)
    Springer
    Pediatric cardiology 6 (1985), S. 25-28 
    Details
    ISSN: 1432-1971
    Keywords: Serum potassium ; KCl ; Cardiac surgery ; Congenital heart defects
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A total of 31 pediatric cardiac patients (mean age 19 ½ months) who required surgery for repair of various congenital heart defects were prospectively studied in the postoperative period to determine potassium (K) dose-response characteristics. All patients received supplementary K when the serum K was 〈4.0 meq/liter. A total of 100 administrations of intravenous potassium chloride (KCl) were evaluated. KCl, 0.5 meq/kg, was infused over 2 h by syringe pump. This infusion was repeated as necessary to achieve a serum K≥4.0 meq/liter. The KCl was administered in addition to the K in the patients' maintenance solution. Blood samples for serum K determination were collected 15–30 min before and after the KCl infusion. The mean K dose administered was 0.72±0.23 meq/kg. This produced a mean rise in serum K of 0.61±0.48 meq/liter. Of 100 administrations, 11 resulted in no change or a decrease in serum K. Four of 100 administrations resulted in serum K〉5.0 meq/liter. Intravenous KCl supplementation in a dose of 0.5 meq/kg administered over 2 h is safe and effective for pediatric postoperative cardiac patients. Serum K should be measured to monitor therapy, due to variable response.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02265404
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  • 5
    Electronic Resource
    Electronic Resource
    Atypical total anomalous pulmonary venous connection: Two channels leading to infracardiac terminations (1989)
    Springer
    Pediatric cardiology 10 (1989), S. 115-120 
    Details
    ISSN: 1432-1971
    Keywords: Pulmonary venous hypertension ; Portal venous system ; Thoracoabdominal veins
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Reported is a rare case of total anomalous pulmonary venous connection (TAPVC) where veins from each lung joined a homolateral confluence. From each confluence, a vein descended into the abdomen, the vein from the right lung joining the ductus venosus, while the vein from the left joined the portal vein. In TAPVC to systemic veins, multiple connections are rare. Multiple connections are most common at supracardiac and cardiac levels, less common at supra- and infracardiac levels, and rare at cardiac and infracardiac levels. From the literature, it is evident that multiple connections at one body level, as in our case, are rare.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02309926
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  • 6
    Electronic Resource
    Electronic Resource
    Learning theories and environments: A student-initiated intelligent computer-assisted environment (1992)
    Springer
    Research in science education 22 (1992), S. 367-376 
    Details
    ISSN: 1573-1898
    Source: Springer Online Journal Archives 1860-2000
    Topics: Natural Sciences in General
    Notes: Abstract Intelligent computer-assisted instructional systems have been constructed and applied within a wide range of fields. Very few of these systems make explicit a central or set of core learning theories or learning environments upon which a system is based. However, many of these systems have implicitly employed learning theories and environments. This paper looks at a variety of intelligent computer-assisted systems with a view towards uncovering the latent learning theories they employ. The interplay of the various learning theories needed to realise a student-initiated learning environment are discussed. The central features required for such an environment to function and the limitations of realising such a learning environment due to the state of the art of present day systems are also discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02356917
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  • 7
    Electronic Resource
    Electronic Resource
    Controlled Delivery of Diphtheria Toxoid Using Biodegradable Poly(D,L-Lactide) Microcapsules (1991)
    Springer
    Pharmaceutical research 8 (1991), S. 958-961 
    Details
    ISSN: 1573-904X
    Keywords: vaccine delivery ; biodegradable microcapsules ; antigen ELISA ; erosion kinetics ; antibody titers
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Diphtheria toxoid, which is an important vaccine in the expanded program of immunization (EPI) in the developing countries, was microencapsulated using poly(D,L,-lactide) of 49,000 molecular weight and the in-water drying technique. The microcapsules were subjected to an in vitro antigen release study using a sensitive enzyme-linked immunosorbent assay (ELISA) developed in the laboratory. Antibody titers in immunized Balb/C mice were also determined using direct ELISA. The antibody units in the immunized group till day 75 were quite comparable to those in the group receiving conventional three-dose injection of diphtheria toxoid with calcium phosphate as an adjuvant. SEM photographs of the micro-capsules during in vitro degradation demonstrated the erosion kinetics of the polymer, leading to controlled release of the antigen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1015832302605
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