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  • 1
    Online Resource
    Online Resource
    SAGE Publications ; 2018
    In:  Waste Management & Research: The Journal for a Sustainable Circular Economy Vol. 36, No. 5 ( 2018-05), p. 445-453
    In: Waste Management & Research: The Journal for a Sustainable Circular Economy, SAGE Publications, Vol. 36, No. 5 ( 2018-05), p. 445-453
    Abstract: In recent years, an increasing number of studies have revealed that plastics and their components (e.g. plasticisers) pose an environmental risk. However, it is hard to imagine how our industrialised society could do without these materials, since the fields of application are manifold. One possible approach to tackle this mounting problem is the implementation of a comprehensive and well-functioning collection and recycling system. An international comparison shows that only a small proportion of the total plastics in circulation is collected and recycled. The investigations conducted under the present research project, ‘Plastic Reborn’, focused on both identification and analysis of the discharge paths of polyolefin-rich waste streams, under the Austrian waste management system. Another objective was determining the utilisation potential of the output fractions of these polyolefin-rich waste streams, generated from a wet mechanical processing pilot plant. Experiments have shown that the polyolefins are successfully separated from the waste streams and that a total polyolefin potential of 429,000 t y −1 remains unexploited in the Austrian waste management system. Thus, these separated plastic fractions can make a significant contribution to the implementation of the European Circular Economy Directive. The residual fractions meet the legal and company-specific requirements for their use as solid recovered fuels in co-combustion plants.
    Type of Medium: Online Resource
    ISSN: 0734-242X , 1096-3669
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
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    detail.hit.zdb_id: 46937-3
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  • 2
    In: Cell Transplantation, SAGE Publications, Vol. 22, No. 11 ( 2013-11), p. 2091-2103
    Abstract: Increased pressure due to postischemic edema aggravates renal ischemia-reperfusion injury (IRI). Prophylactic surgical decompression using microcapsulotomy improves kidney dysfunction after IRI. Supportive cell therapy in combination with microcapsulotomy might act synergistically protecting kidney function against IRI. The effects of therapeutic endothelial cell application alone and in combination with microcapsulotomy were investigated in a xenogenic murine model of 45-min warm renal ischemia. Renal function and perfusion were determined before as well as 2 and 18 days postischemia by 99m Tc-MAG3 imaging and laser Doppler. Histological analysis included H & E stains and immunohistology for endothelial marker MECA-32, cell proliferation marker Ki-67, and macrophage marker F4/80. Histomorphological changes were quantified using a tubular injury score. Ischemia of 45 min led to severe tissue damage and a significant decrease in renal function and perfusion. Microcapsulotomy and cell therapy alone had no significant effect on renal function, while only surgical decompression significantly increased blood flow in ischemic kidneys. However, the combination of both microcapsulotomy and cell therapy significantly improved kidney function and perfusion. Combination therapy significantly reduced morphological injury of ischemic kidneys as determined by a tubular injury score and MECA-32 staining. Macrophage infiltration evidenced by F4/80 staining was significantly reduced. The Ki-67 proliferation index was increased, suggesting a regenerative environment. While microcapsulotomy and cell therapy alone have limited effect on renal recovery after IRI, combination therapy showed synergistic improvement of renal function, perfusion, and structural damage. Microcapsulotomy may create a permissive environment for cell therapy to work.
    Type of Medium: Online Resource
    ISSN: 0963-6897 , 1555-3892
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2013
    detail.hit.zdb_id: 2020466-8
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