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  • 1
    Online Resource
    Online Resource
    Organizational Use of a Media Campaign Booklet to Encourage Parent–Child Communication about Waiting to Have Sex
    SAGE Publications ; 2011
    In:  Social Marketing Quarterly Vol. 17, No. 1 ( 2011-03), p. 91-107
    Details
    In: Social Marketing Quarterly, SAGE Publications, Vol. 17, No. 1 ( 2011-03), p. 91-107
    Abstract: Promoting parent—child communication through the use of print materials may be an important health communication approach for preventing teen sexual activity in the United States. Although prior work has suggested successful methods of disseminating print materials, research has not examined dissemination approaches across organization types. Understanding the use and dissemination of print materials among different organizations is crucial to guiding materials development in a way that maximizes uptake and effectiveness among consumers. Accordingly, this study examined the use of a booklet for parents that encouraged parent–child communication about waiting to have sex as collateral material for a national media campaign. We interviewed staff at 9 community organizations, 9 health care facilities, 5 school-based organizations, and 3 campaign outreach centers. Results suggested variability within and across organization types regarding use of the booklet. Community and outreach center staff tended to walk through the booklet content with parents; health care facilities and education-oriented organizations usually reported both direct and indirect distribution approaches. Staff identified useful elements of the booklet and made suggestions for dissemination in line with prior research. A better understanding of how print materials are utilized to supplement media campaigns can improve their usefulness and potential influence on health behaviors.
    Type of Medium: Online Resource
    ISSN: 1524-5004 , 1539-4093
    URL: Article
    DOI: 10.1080/15245004.2011.547143
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2011
    detail.hit.zdb_id: 2086163-1
    SSG: 3,2
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  • 2
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    Metabolic regional and network changes in Alzheimer's disease subtypes
    SAGE Publications ; 2018
    In:  Journal of Cerebral Blood Flow & Metabolism Vol. 38, No. 10 ( 2018-10), p. 1796-1806
    Details
    In: Journal of Cerebral Blood Flow & Metabolism, SAGE Publications, Vol. 38, No. 10 ( 2018-10), p. 1796-1806
    Abstract: Clinical variants of Alzheimer's disease (AD) include the common amnestic subtype as well as subtypes characterised by leading visual processing impairments or by multimodal neurocognitive deficits. We investigated regional metabolic patterns and networks between AD subtypes. The study comprised 9 age-matched controls and 25 patients with mild to moderate AD. Methods included clinical and neuropsychological assessment, high-resolution FDG PET and T1-weighted 3D MR imaging with PET-MR coregistration, grey matter segmentation, atlas-based regions-of-interest, linear mixed effects and regional correlation analysis. Regional metabolic patterns differed significantly between groups, but significant hypometabolism in the posterior cingulate cortex (PCC) was common to all subtypes. The most distinctive regional abnormality was occipital hypometabolism in the visual subtype. In controls, two large clusters of positive regional metabolic correlations were observed. The most pronounced breakdown of the normal correlation pattern was found in amnestic patients who, in contrast, showed the least regional focal metabolic deficits. The normal positive correlation between PCC and hippocampus was lost in all subtypes. In conclusion, PCC hypometabolism and metabolic correlation breakdown between PCC and hippocampus are the common functional core of all AD subtypes. Network alterations exceed focal regional impairment and are most prominent in the amnestic subtype.
    Type of Medium: Online Resource
    ISSN: 0271-678X , 1559-7016
    URL: Article
    DOI: 10.1177/0271678X17718436
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2039456-1
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  • 3
    Online Resource
    Online Resource
    Effects of Gender and Dress on Helping Behavior
    SAGE Publications ; 1996
    In:  Psychological Reports Vol. 78, No. 3 ( 1996-06), p. 987-994
    Details
    In: Psychological Reports, SAGE Publications, Vol. 78, No. 3 ( 1996-06), p. 987-994
    Abstract: The effects of gender and dress on helping behavior were examined. Perceptions and feelings influencing decisions to help were also investigated in an exploratory manner. 128 subjects were asked by a male or female confederate for 37¢ and afterwards completed a questionnaire. The confederates were either well-dressed or sloppily dressed. Analysis indicated that the woman was helped more than the man but that well-dressed and sloppily dressed confederates were helped equally. Subjects who helped generally perceived confederates to be needier than subjects who did not. Further, subjects who did not help reported greater discomfort from the helping request than subjects who helped.
    Type of Medium: Online Resource
    ISSN: 0033-2941 , 1558-691X
    URL: Article
    DOI: 10.2466/pr0.1996.78.3.987
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1996
    detail.hit.zdb_id: 2066930-6
    SSG: 5,2
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  • 4
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    Online Resource
    ManyClasses 1: Assessing the Generalizable Effect of Immediate Feedback Versus Delayed Feedback Across Many College Classes
    SAGE Publications ; 2021
    In:  Advances in Methods and Practices in Psychological Science Vol. 4, No. 3 ( 2021-07), p. 251524592110275-
    Details
    In: Advances in Methods and Practices in Psychological Science, SAGE Publications, Vol. 4, No. 3 ( 2021-07), p. 251524592110275-
    Abstract: Psychology researchers have long attempted to identify educational practices that improve student learning. However, experimental research on these practices is often conducted in laboratory contexts or in a single course, which threatens the external validity of the results. In this article, we establish an experimental paradigm for evaluating the benefits of recommended practices across a variety of authentic educational contexts—a model we call ManyClasses. The core feature is that researchers examine the same research question and measure the same experimental effect across many classes spanning a range of topics, institutions, teacher implementations, and student populations. We report the first ManyClasses study, in which we examined how the timing of feedback on class assignments, either immediate or delayed by a few days, affected subsequent performance on class assessments. Across 38 classes, the overall estimate for the effect of feedback timing was 0.002 (95% highest density interval = [−0.05, 0.05]), which indicates that there was no effect of immediate feedback compared with delayed feedback on student learning that generalizes across classes. Furthermore, there were no credibly nonzero effects for 40 preregistered moderators related to class-level and student-level characteristics. Yet our results provide hints that in certain kinds of classes, which were undersampled in the current study, there may be modest advantages for delayed feedback. More broadly, these findings provide insights regarding the feasibility of conducting within-class randomized experiments across a range of naturally occurring learning environments.
    Type of Medium: Online Resource
    ISSN: 2515-2459 , 2515-2467
    URL: Article
    DOI: 10.1177/25152459211027575
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2904847-3
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  • 5
    Online Resource
    Online Resource
    Outcome measures in a combined exercise rehabilitation programme for adults with COPD and chronic heart failure: A preliminary stakeholder consensus event
    SAGE Publications ; 2019
    In:  Chronic Respiratory Disease Vol. 16 ( 2019-01-01), p. 147997311986795-
    Details
    In: Chronic Respiratory Disease, SAGE Publications, Vol. 16 ( 2019-01-01), p. 147997311986795-
    Abstract: Combined exercise rehabilitation for chronic obstructive pulmonary disease (COPD) and chronic heart failure (CHF) is potentially attractive. Uncertainty remains as to the baseline profiling assessments and outcome measures that should be collected within a programme. Current evidence surrounding outcome measures in cardiac and pulmonary rehabilitation were presented by experts at a stakeholder consensus event and all stakeholders ( n = 18) were asked to (1) rank in order of importance a list of categories, (2) prioritise outcome measures and (3) prioritise baseline patient evaluation measures that should be assessed in a combined COPD and CHF rehabilitation programme. The tasks were completed anonymously and related to clinical rehabilitation programmes and associated research. Health-related quality of life, exercise capacity and symptom evaluation were voted as the most important categories to assess for clinical purposes (median rank: 1, 2 and 3 accordingly) and research purposes (median rank; 1, 3 and 4.5 accordingly) within combined exercise rehabilitation. All stakeholders agreed that profiling symptoms at baseline were ‘moderately’, ‘very’ or ‘extremely’ important to assess for clinical and research purposes in combined rehabilitation. Profiling of frailty was ranked of the same importance for clinical purposes in combined rehabilitation. Stakeholders identified a suite of multidisciplinary measures that may be important to assess in a combined COPD and CHF exercise rehabilitation programme.
    Type of Medium: Online Resource
    ISSN: 1479-9731 , 1479-9731
    URL: Article
    DOI: 10.1177/1479973119867952
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2222367-8
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  • 6
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    Improving Justice for American Indian and Rural Victims of Crime Through Community-Engaged Research
    SAGE Publications ; 2021
    In:  Journal of Contemporary Criminal Justice Vol. 37, No. 2 ( 2021-05), p. 192-211
    Details
    In: Journal of Contemporary Criminal Justice, SAGE Publications, Vol. 37, No. 2 ( 2021-05), p. 192-211
    Abstract: Community-engaged research can be effective in directly improving justice for individuals and communities, and to guide policies and practices. Given the challenges to accessing some populations of interest, such as with rural victims of crime, community-engaged approaches provide a means to support ethical and culturally competent research that can improve justice in a meaningful way. In this article, we discuss a collaborative research partnership between academic researchers and a victim service agency that sought to connect rural victim advocacy with a data-driven research methodology for improved justice delivery in two communities with differing rural dynamics. Researchers and practitioners can benefit from recognizing the unique, yet varied, victimization experiences within rural communities, and an understanding of this variability among rural victims and contexts can inform justice practice. We provide best practice recommendations from both researcher and practitioner perspectives for the successful implementation of a project that serves victims in the community and through policy. Implications for justice-related policy and practice for rural and American Indian crime victims are discussed.
    Type of Medium: Online Resource
    ISSN: 1043-9862 , 1552-5406
    URL: Article
    DOI: 10.1177/1043986221999859
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2027876-7
    SSG: 2
    SSG: 2,1
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  • 7
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    Online Resource
    Identifying Vulnerable Plaque in Rheumatoid Arthritis Using Novel Microbubble Contrast-Enhanced Carotid Ultrasonography and Serum Biomarkers
    SAGE Publications ; 2020
    In:  Journal of Diagnostic Medical Sonography Vol. 36, No. 4 ( 2020-07), p. 300-310
    Details
    In: Journal of Diagnostic Medical Sonography, SAGE Publications, Vol. 36, No. 4 ( 2020-07), p. 300-310
    Abstract: Rheumatoid arthritis (RA) is associated with increased risk of cardiovascular disease. Adventitial vasa vasorum density (aVVD), the vessel density of the vasa vasorum, is a surrogate measure for atherosclerotic plaque vulnerability. The purpose of this study was to compare the adventitial vasa vasorum density (aVVD) in RA and non-RA control participants using novel carotid artery contrast-enhanced ultrasound (CEUS). In addition, we investigate associations of aVVD with traditional cardiovascular (CV) risk factors, vascular and inflammatory biomarkers, and RA disease activity. Methods: The study was a cross-sectional analysis of patients with RA and control participants without RA or other autoimmune disease. CV disease risk, biomarkers, and CEUS images were collected on all patients. Results: aVVD was quantified in 86 patients with RA and 95 non-RA control participants. Nitrite, CD40L, E-selectin, matrix metalloproteinase 9, intercellular adhesion molecule 1, vascular cell adhesion molecule 1, myeloperoxidase (MPO), high-sensitivity C-reactive protein (hsCRP), and erythrocyte sedimentation rate were measured. Median aVVD was higher in patients with RA (0.59 [0.47–0.69] vs 0.64 [0.54–0.62] ; P = .02). In patients with RA, MPO was lower (253.5 [153.2–480] vs 470.8 [274.2–830.1] ng/mL; P = .0002) and ESR was higher (15.5 [11–25] vs 13 [9–20 ] mm/h; P = .02). aVVD was correlated with MPO ( r = −0.33, P = .001) and hsCRP ( r = 0.25, P = .02) in control participants only, associations that remained significant after adjusting for number of CV risk factors and age. No significant correlations were found between aVVD and RA disease activity measures. Conclusions: Using a novel application of CEUS, we found that aVVD, an early measure of plaque vulnerability, was significantly higher in RA than control subjects, even after adjusting for CV risk factors. Differences in correlation of aVVD with vascular biomarkers and CV risk factors suggest RA-related differences in atherosclerotic progression.
    Type of Medium: Online Resource
    ISSN: 8756-4793 , 1552-5430
    URL: Article
    DOI: 10.1177/8756479320922512
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2040352-5
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  • 8
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    Online Resource
    Procedural and declarative memory task performance, and the memory consolidation function of sleep, in recent and abstinent ecstasy/MDMA users
    SAGE Publications ; 2011
    In:  Journal of Psychopharmacology Vol. 25, No. 4 ( 2011-04), p. 465-477
    Details
    In: Journal of Psychopharmacology, SAGE Publications, Vol. 25, No. 4 ( 2011-04), p. 465-477
    Abstract: Ecstasy/MDMA use has been associated with various memory deficits. This study assessed declarative and procedural memory in ecstasy/MDMA users. Participants were tested in two sessions, 24 h apart, so that the memory consolidation function of sleep on both types of memory could also be assessed. Groups were: drug-naive controls ( n = 24); recent ecstasy/MDMA users, who had taken ecstasy/MDMA 2–3 days before the first testing session ( n = 25), and abstinent users, who had not taken ecstasy/MDMA for at least 8 days before testing ( n = 17). Procedural memory did not differ between groups, but greater lifetime consumption of ecstasy was associated with poorer procedural memory. Recent ecstasy/MDMA users who had taken other drugs (mainly cannabis) 48–24 h before testing exhibited poorer declarative memory than controls, but recent users who had not taken other drugs in this 48–24-h period did not differ from controls. Greater lifetime consumption of ecstasy, and of cocaine, were associated with greater deficits in declarative memory. These results suggest that procedural, as well as declarative, memory deficits are associated with the extent of past ecstasy use. However, ecstasy/MDMA did not affect the memory consolidation function of sleep for either the declarative or the procedural memory task.
    Type of Medium: Online Resource
    ISSN: 0269-8811 , 1461-7285
    URL: Article
    DOI: 10.1177/0269881110372545
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2011
    detail.hit.zdb_id: 2028926-1
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  • 9
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    Online Resource
    Preclinical Safety and Pharmacokinetics of Recombinant Human Factor XIII
    SAGE Publications ; 2005
    In:  Toxicologic Pathology Vol. 33, No. 4 ( 2005-06), p. 495-506
    Details
    In: Toxicologic Pathology, SAGE Publications, Vol. 33, No. 4 ( 2005-06), p. 495-506
    Abstract: Factor XIII (FXIII) is a thrombin-activated protransglutaminase responsible for fibrin clot stabilization and longevity. Deficiency in FXIII is associated with diffuse bleeding and wound-healing disorders in humans. This report summarizes results from several studies conducted in adult cynomolgus monkeys ( M. fascicularis) to evaluate the safety and pharmacokinetics of recombinant human factor XIII A 2 dimer (rFXIII). Intravenous slow bolus injection of rFXIII resulted in the expected formation of the heterotetramer rA 2 cnB 2 , prolonged circulating half-life (5–7 days), and increased plasma transglutaminase activity. Recombinant FXIII was well tolerated as a single dose up to 20 mg/kg rFXIII (2840 U/kg), as repeated daily doses up to 6 mg/kg (852 U/kg) for 14 days, and as 3 repeated doses of 8 mg/kg (1136 U/kg) separated by 14 days. Overt toxicity occurred after a single intravenous injection of ≥ 22.5 mg/kg rFXIII (3150 U/kg), or with 2 doses of =12.5 mg/kg (1775 U/kg) administered within 72 hours. The rFXIII-mediated toxicity was expressed as an acute systemic occlusive coagulopathy. Evaluation of plasma samples from dosed animals demonstrated formation of cross-linked fibrin/fibrinogen oligomers and higher-order protein aggregates, which are hypothesized to be responsible for the observed vessel occlusion and associated embolic sequelae. These results demonstrate that rFXIII-mediated toxicity results from exaggerated pharmacological activity of the molecule at supraphysiological concentrations. The absence of observed toxicological effect with repeated intravenous doses up to 8 mg/kg (1136 U/kg) was used to support an initial clinical dose range of 0.014 to 0.35 mg/kg (2–50 U/kg).
    Type of Medium: Online Resource
    ISSN: 0192-6233 , 1533-1601
    URL: Article
    DOI: 10.1080/01926230490966247
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2005
    detail.hit.zdb_id: 2056753-4
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  • 10
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    Comparison of chemotherapy education and patient preferences in community versus academic gynecology oncology clinics a
    SAGE Publications ; 2008
    In:  Journal of Oncology Pharmacy Practice Vol. 14, No. 1 ( 2008-03), p. 31-36
    Details
    In: Journal of Oncology Pharmacy Practice, SAGE Publications, Vol. 14, No. 1 ( 2008-03), p. 31-36
    Abstract: Purpose. To evaluate and compare patients' preferences in receiving chemotherapy education from health care teams in community versus academic clinics. Methods. Results from a 13-question questionnaire about the chemotherapy education preferences of patients in three community gynecology oncology clinics were compared to the results from a similar study previously conducted in an academic gynecology oncology clinic. Results. A total of 57% of the 203 communityclinic respondents (116) and 67% of the 282 academic-institution respondents (189) who completed questionnaires had previously received chemotherapy. Of the patients treated in community clinics, almost 60% preferred chemotherapy education to be provided in written form and directly by a health care professional compared to 87% of the patients in academic clinics. Overall, 88% of the patients in the community clinics believed they received adequate information, compared to 63% of the patients in the academic setting. Patients in the community clinics wanted to get more in-depth answers to questions such as `What is chemotherapy?' (54%) and `How it is given?' (55%). In addition, community patients also wanted to know more about `Why chemotherapy stops working?' (72%) and `What to do and who to call about side effects?' (60%). In the academic setting, patients were less likely to want to know more about these chemotherapy related questions (42, 35, 57, and 49, respectively). Conclusions. Patients preferred to receive written chemotherapy education that was reviewed with a healthcare professional and that gave more detailed information about the chemotherapeutic drugs themselves and how to prevent and manage side effects. As a result of this questionnaire, the patient education materials used at our institution will be revised to better address patients' preferences in both treatment settings. J Oncol Pharm Practice (2008) 14: 31—36.
    Type of Medium: Online Resource
    ISSN: 1078-1552 , 1477-092X
    URL: Article
    DOI: 10.1177/1078155207082947
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2008
    detail.hit.zdb_id: 2026590-6
    SSG: 15,3
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