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  • 1
    Online Resource
    Online Resource
    SAGE Publications ; 1983
    In:  Annals of Clinical Biochemistry: International Journal of Laboratory Medicine Vol. 20, No. 5 ( 1983-09), p. 271-273
    In: Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, SAGE Publications, Vol. 20, No. 5 ( 1983-09), p. 271-273
    Abstract: The observation that the ionised calcium concentration is higher if measured in the original serum sample than in an ultrafiltrate is examined by means of a theoretical model. It is concluded that this difference is a predictable consequence of the Donnan equilibrium and is not a result of protein interference with the calcium-specific electrode.
    Type of Medium: Online Resource
    ISSN: 0004-5632 , 1758-1001
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1983
    detail.hit.zdb_id: 2041298-8
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  • 2
    Online Resource
    Online Resource
    SAGE Publications ; 2012
    In:  Project Management Journal Vol. 43, No. 2 ( 2012-04), p. 37-53
    In: Project Management Journal, SAGE Publications, Vol. 43, No. 2 ( 2012-04), p. 37-53
    Abstract: We consider identification of early warning signs (EWS) in projects. Project professionals are not good at detecting or acting on EWS. Barriers that lead to this are identified. The nature of EWS and their detection change with the evolving situation. Project assessments, typically part of gateways, are useful in identifying EWS connected to the formalities of the project. As complexity increases, assessments have more limited use, and the project is increasingly dependent on detecting EWS by informal “gut feeling.” Thus, knowledge, experience, and communication skills are increasingly important in complex situations. We conclude with a list of early warning signs.
    Type of Medium: Online Resource
    ISSN: 8756-9728 , 1938-9507
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2012
    detail.hit.zdb_id: 2070979-1
    SSG: 3,2
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  • 3
    In: Health Informatics Journal, SAGE Publications, Vol. 26, No. 4 ( 2020-12), p. 2492-2511
    Abstract: Telerehabilitation programs can be employed to establish communication between patients and healthcare professionals and empower patients performing their training remotely. This study aimed to identify patients’ requirements after a total knee replacement following a self-training rehabilitation program, leading to the design and development of a telerehabilitation program that can meet the stakeholders’ actual needs. System design, development, and testing were conducted in five iterations based on a participatory design approach. Data collection was performed using interviews, observations, prototyping, and questionnaires. It was found that the main barriers facing the existing rehabilitation program were a lack of clear communication, lack of relevant information, and healthcare professional’s feedback. The participants emphasized the main themes of communication, information, training, and motivation in the process of design and development. In using the telerehabilitation program, the patients reported a high level of user-friendliness, flexibility, and a sense of security. This study has identified obstacles in the current rehabilitation program and revealed the potential effectiveness of using asynchronous communication and sensor-based technologies by employing participatory design and development. A higher level of portability and flexibility were observed. However, future studies and development are required to investigate the overall usability and reliability of the telerehabilitation program.
    Type of Medium: Online Resource
    ISSN: 1460-4582 , 1741-2811
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2070802-6
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  • 4
    Online Resource
    Online Resource
    SAGE Publications ; 2012
    In:  Evaluation Vol. 18, No. 1 ( 2012-01), p. 47-59
    In: Evaluation, SAGE Publications, Vol. 18, No. 1 ( 2012-01), p. 47-59
    Abstract: Part of the justification for joint-donor evaluations is that they allow the conduct of relevant evaluations with a broader scope than single-donor evaluations and at the same time reduce transaction costs. Many joint-donor evaluations, however, run into management and coordination problems, have unforeseen high transaction costs for the donors and result in general conclusions and recommendations. The purpose of this article is to contribute to a better understanding of the factors that influence how donor-evaluation units engage in joint evaluations and to identify mechanisms that can make them more effective. It represents a first step towards analysing joint evaluations using a political-economy perspective based on assumptions about the interests and incentives of donor management, evaluations units and evaluators. The article argues that the broader scope of many joint-donor evaluations and their relatively high transaction costs are closely related to and originate from differences in donor interests and incentive structures, and an insufficient focus on methodological challenges. The article concludes with a number of tentative operational suggestions based on the analyses.
    Type of Medium: Online Resource
    ISSN: 1356-3890 , 1461-7153
    RVK:
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2012
    detail.hit.zdb_id: 2033688-3
    SSG: 3,4
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  • 5
    In: Childhood, SAGE Publications
    Abstract: The purpose of this study is to illuminate how participatory methods over time in a research project with disabled children may contribute to an empowerment process. Findings indicate that appropriate use of participatory methods over time may contribute to an empowerment process with disabled children. Based on the UNCRC article 12, this paper calls for seizing the great potential that lies in building on disabled children’s inner strength and efforts to increase their own power in research processes.
    Type of Medium: Online Resource
    ISSN: 0907-5682 , 1461-7013
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 1483566-6
    SSG: 5,2
    SSG: 5,3
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  • 6
    Online Resource
    Online Resource
    SAGE Publications ; 1975
    In:  Proceedings of the Royal Society of Medicine Vol. 68, No. 4 ( 1975-04), p. 259-259
    In: Proceedings of the Royal Society of Medicine, SAGE Publications, Vol. 68, No. 4 ( 1975-04), p. 259-259
    Type of Medium: Online Resource
    ISSN: 0035-9157
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1975
    detail.hit.zdb_id: 2046643-2
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  • 7
    Online Resource
    Online Resource
    SAGE Publications ; 2008
    In:  Administration & Society Vol. 40, No. 1 ( 2008-03), p. 54-78
    In: Administration & Society, SAGE Publications, Vol. 40, No. 1 ( 2008-03), p. 54-78
    Abstract: The article focuses on a kind of innovation trajectory, based on the reemployment of assets that belong to the legacy of the past. Thus, it argues for the importance of utilizing know-how and social capital accumulated over the years in organizations' efforts to launch a new course. The concept of bricolage appears especially clarifying in throwing light on innovations emerging through bottom-up processes, utilizing what is at hand or embedded locally. However important breakthrough and pioneering entrepreneurs might be, what really matters in the long run is more incremental processes of problem solving. In elaborating this view on innovation, the article addresses organizational devolution and partnership. According to the article, top-down steering or strategic determination do not suffice to account for the processes underlying the application of these tools. Innovative processes of bricolage based on a bottom-up mobilization appear pivotal for releasing creativity.
    Type of Medium: Online Resource
    ISSN: 0095-3997 , 1552-3039
    RVK:
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2008
    detail.hit.zdb_id: 1499970-5
    SSG: 2
    SSG: 3,4
    SSG: 3,7
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  • 8
    In: Technology in Cancer Research & Treatment, SAGE Publications, Vol. 16, No. 4 ( 2017-08), p. 406-413
    Abstract: The present study investigates how computed tomography perfusion scans and magnetic resonance imaging correlates with the histopathological alterations in renal tissue after cryoablation. A total of 15 pigs were subjected to laparoscopic-assisted cryoablation on both kidneys. After intervention, each animal was randomized to a postoperative follow-up period of 1, 2, or 4 weeks, after which computed tomography perfusion and magnetic resonance imaging scans were performed. Immediately after imaging, open bilateral nephrectomy was performed allowing for histopathological examination of the cryolesions. On computed tomography perfusion and magnetic resonance imaging examinations, rim enhancement was observed in the transition zone of the cryolesion 1week after laparoscopic-assisted cryoablation. This rim enhancement was found to subside after 2 and 4 weeks of follow-up, which was consistent with the microscopic examinations revealing of fibrotic scar tissue formation in the peripheral zone of the cryolesion. On T2 magnetic resonance imaging sequences, a thin hypointense rim surrounded the cryolesion, separating it from the adjacent renal parenchyma. Microscopic examinations revealed hemorrhage and later hemosiderin located in the peripheral zone. No nodular or diffuse contrast enhancement was found in the central zone of the cryolesions at any follow-up stage on neither computed tomography perfusion nor magnetic resonance imaging. On microscopic examinations, the central zone was found to consist of coagulative necrosis 1 week after laparoscopic-assisted cryoablation, which was partially replaced by fibrotic scar tissue 4 weeks following laparoscopic-assisted cryoablation. Both computed tomography perfusion and magnetic resonance imaging found the renal collecting system to be involved at all 3 stages of follow-up, but on microscopic examination, the urothelium was found to be intact in all cases. In conclusion, cryoablation effectively destroyed renal parenchyma, leaving the urothelium intact. Both computed tomography perfusion and magnetic resonance imaging reflect the microscopic findings but with some differences, especially regarding the peripheral zone. Magnetic resonance imaging seems an attractive modality for early postoperative follow-up.
    Type of Medium: Online Resource
    ISSN: 1533-0346 , 1533-0338
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2146365-7
    detail.hit.zdb_id: 2220436-2
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  • 9
    In: Journal of Diabetes Science and Technology, SAGE Publications, Vol. 9, No. 5 ( 2015-09-01), p. 1092-1102
    Abstract: The use of continuous glucose monitoring (CGM) in clinical decision making in diabetes could be limited by the inaccuracy of CGM data when compared to plasma glucose measurements. The aim of the present study is to investigate the impact of CGM numerical accuracy on the precision of diabetes treatment adjustments. Method: CGM profiles with maximum 5-day duration from 12 patients with type 1 diabetes treated with a basal-bolus insulin regimen were processed by 2 CGM algorithms, with the accuracy of algorithm 2 being higher than the accuracy of algorithm 1, using the median absolute relative difference (MARD) as the measure of accuracy. During 2 separate and similar occasions over a 1-month interval, 3 clinicians reviewed the processed CGM profiles, and adjusted the dose level of basal and prandial insulin. The precision of the dosage adjustments were defined in terms of the interclinician agreement and the intraclinician reproducibility of the decisions. The Cohen’s kappa coefficient was used to assess the precision of the decisions. The study was based on retrospective and blind CGM data. Results: For the interclinician agreement, in the first occasion, the kappa of algorithm 1 was .32, and that of algorithm 2 was .36. For the interclinician agreement, in the second occasion, the kappas of algorithms 1 and 2 were .17 and .22, respectively. For the intraclinician reproducibility of the decisions, the kappas of algorithm 1 were .35, .22, and .80 and the kappas of algorithm 2 were .44, .52, and .32, for the 3 clinicians, respectively. For the interclinician agreement, the relative kappa change from algorithm 1 to algorithm 2 was 86.06%, and for the intraclinician reproducibility, the relative kappa change from algorithm 1 to algorithm 2 was 53.99%. Conclusions: Results indicated that the accuracy of CGM algorithms might potentially affect the precision of the CGM-based insulin adjustments for type 1 diabetes patients. However, a larger study with several clinical centers, with higher number of clinicians and patients is required to validate the impact of CGM accuracy on decisions precision.
    Type of Medium: Online Resource
    ISSN: 1932-2968 , 1932-2968
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2467312-2
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  • 10
    In: Journal of Diabetes Science and Technology, SAGE Publications, Vol. 17, No. 3 ( 2023-05), p. 794-825
    Abstract: Previous systematic reviews have aimed to clarify the effect of telemedicine on diabetes. However, such reviews often have a narrow focus, which calls for a more comprehensive systematic review within the field. Hence, the objective of the present systematic review, meta-analysis, and meta-regression is to evaluate the effectiveness of telemedicine solutions versus any comparator without the use of telemedicine on diabetes-related outcomes among adult patients with type 2 diabetes (T2D). Methods: This review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. We considered telemedicine randomized controlled trials (RCT) including adults (≥18 years) diagnosed with T2D. Change in glycated hemoglobin (HbA1c, %) was the primary outcome. PubMed, EMBASE, and the Cochrane Library Central Register of Controlled Trials (CENTRAL) were searched on October 14, 2020. An overall treatment effect was estimated using a meta-analysis performed on the pool of included studies based on the mean difference (MD). The revised Cochrane risk-of-bias tool was applied and the certainty of evidence was graded using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach. Results: The final sample of papers included a total of 246, of which 168 had sufficient information to calculate the effect of HbA1c%. The results favored telemedicine, with an MD of −0.415% (95% confidence interval [CI] = −0.482% to −0.348%). The heterogeneity was great (I 2 = 93.05%). A monitoring component gave rise to the higher effects of telemedicine. Conclusions: In conclusion, telemedicine may serve as a valuable supplement to usual care for patients with T2D. The inclusion of a telemonitoring component seems to increase the effect of telemedicine.
    Type of Medium: Online Resource
    ISSN: 1932-2968 , 1932-2968
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2467312-2
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