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  • Hindawi Limited  (5)
  • 1
    Online Resource
    Online Resource
    Albumin Binding Function: The Potential Earliest Indicator for Liver Function Damage
    Hindawi Limited ; 2016
    In:  Gastroenterology Research and Practice Vol. 2016 ( 2016), p. 1-7
    Details
    In: Gastroenterology Research and Practice, Hindawi Limited, Vol. 2016 ( 2016), p. 1-7
    Abstract: Background . Currently there is no indicator that can evaluate actual liver lesion for early stages of viral hepatitis, nonalcoholic fatty liver disease (NAFLD), and cirrhosis. Aim of this study was to investigate if albumin binding function could better reflect liver function in these liver diseases. Methods . An observational study was performed on 193 patients with early NAFLD, viral hepatitis, and cirrhosis. Cirrhosis patients were separated according to Child-Pugh score into A, B, and C subgroup. Albumin metal ion binding capacity (Ischemia-modified albumin transformed, IMAT) and fatty acid binding capacity (total binding sites, TBS) were detected. Results . Both IMAT and TBS were significantly decreased in patients with NAFLD and early hepatitis. In hepatitis group, they declined prior to changes of liver enzymes. IMAT was significantly higher in cirrhosis Child-Pugh class A group than hepatitis patients and decreased in Child-Pugh class B and class C patients. Both IMAT/albumin and TBS/albumin decreased significantly in hepatitis and NAFLD group patients. Conclusions . This is the first study to discover changes of albumin metal ion and fatty acid binding capacities prior to conventional biomarkers for liver damage in early stage of liver diseases. They may become potential earliest sensitive indicators for liver function evaluation.
    Type of Medium: Online Resource
    ISSN: 1687-6121 , 1687-630X
    URL: Article
    DOI: 10.1155/2016/5120760
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2016
    detail.hit.zdb_id: 2435460-0
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  • 2
    Online Resource
    Online Resource
    A Lamus-Based Flight Data Sharing Model on Consortium Blockchain
    Hindawi Limited ; 2022
    In:  Security and Communication Networks Vol. 2022 ( 2022-5-9), p. 1-11
    Details
    In: Security and Communication Networks, Hindawi Limited, Vol. 2022 ( 2022-5-9), p. 1-11
    Abstract: Currently, traditional flight data sharing models cannot resist quantum attacks, which poses the risk of data leakage. The research on the flight data sharing model against quantum attack has become one of the research hotspots. Lattice-based cryptography is recognized as an effective way to resist quantum attacks. A flight data sharing model on consortium blockchain is proposed in this paper to resolve data leakage during data sharing. First, a new lattice-based multisignature scheme (Lamus) is proposed, capable of resisting quantum attacks. We prove the security of the proposed Lamus scheme in the random oracle model. Moreover, a flight data sharing model on consortium blockchain is proposed by applying the proposed Lamus scheme to resist quantum attacks. Security and performance analysis show that the model guarantees antiquantum security, and it achieves good performance in terms of storage efficiency and operating efficiency.
    Type of Medium: Online Resource
    ISSN: 1939-0122 , 1939-0114
    URL: Article
    DOI: 10.1155/2022/5717185
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2022
    detail.hit.zdb_id: 2415104-X
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  • 3
    Online Resource
    Online Resource
    The Number of Patients with Acute Myocardial Infarction Decreased and Door-to-Balloon Time Delayed in COVID-19
    Hindawi Limited ; 2021
    In:  Cardiology Research and Practice Vol. 2021 ( 2021-3-25), p. 1-6
    Details
    In: Cardiology Research and Practice, Hindawi Limited, Vol. 2021 ( 2021-3-25), p. 1-6
    Abstract: Background. At present, COVID-19 is sweeping the world, and all countries are actively responding. During the COVID-19 epidemic, the treatment of patients with acute myocardial infarction (AMI) may be affected. Methods. We reviewed data of patients with AMI from January 23 to April 23, 2020 (2020), and January 23 to April 23, 2019 (2019), who were admitted to two hospitals from Southern China. We collected clinical characteristics, comorbidities, treatment, prognosis, and key time segments to analyze. Results. The total number of patients that had been diagnosed with AMI in the two hospitals was 218 in 2020 and 260 in 2019. The number of AMI patients that were admitted to hospitals per day decreased in 2020. The percentage of patients with AMI who refused hospitalization in 2020 was significantly higher than that in 2019 (5.0% vs 1.5%, p = 0.028 ). There is no statistical difference in symptoms of the first medical contact (S2FMC) time between 2020 and 2019 ( p = 0.552 ). Door-to-balloon (D2B) time of ST-elevation myocardial infarction (STEMI) patients who were treated with a primary percutaneous coronary intervention (pPCI) in 2020 was 79 (63.75–105.25) mins, while D2B time in 2019 was 57.5 (41.5–76.5) mins, which was statistically different from the two groups. Conclusions. COVID-19 had an impact on the number of AMI patients who were admitted to hospitals and the time of treatment. During the COVID-19 epidemic, the number of AMI patients that were admitted to hospitals per day was decreased, while the percentage of AMI patients that refused therapy in these two hospitals increased, and the D2B time of STEMI patients was also delayed.
    Type of Medium: Online Resource
    ISSN: 2090-0597 , 2090-8016
    URL: Article
    DOI: 10.1155/2021/6673313
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2021
    detail.hit.zdb_id: 2506187-2
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  • 4
    Online Resource
    Online Resource
    Investigation of Unsteady Pressure Pulsation in New Type Dishwasher Pump with Special Double Tongue Volute
    Hindawi Limited ; 2022
    In:  Shock and Vibration Vol. 2022 ( 2022-1-12), p. 1-11
    Details
    In: Shock and Vibration, Hindawi Limited, Vol. 2022 ( 2022-1-12), p. 1-11
    Abstract: Through numerical simulations, this work analyzes the unsteady pressure pulsation characteristics in new type of dishwasher pump with double tongue volute and single tongue volute, under volute static and rotation conditions. Likewise, the performance tests were also carried out to verify the numerical results. Multiple monitoring points were set at the various positions of new type dishwasher pump to collect the pressure pulsation signals, and the relevant frequency signals were obtained via Fast Fourier Transform, to analyze the influence of volute tongue and its passive speed on the pump performance. The results reveal that when the double tongue volute is stationary, the pressure pulsation amplitudes increase from the impeller inlet to the impeller outlet. Under the influence of shedding vortex, the pressure pulsation in the lateral region of tongue becomes disorganized, and the main frequency of pressure pulsation changes from blade frequency to shaft frequency. In addition, compared with the static volute, double tongue volute can effectively guide the water flow out of the tongue during the rotation process, thus ensuring good periodicity for pressure pulsation in the tongue region. Accordingly, a volute reference scheme with passive rotation speed is proposed in this study, which can effectively improve the pressure pulsation at tongue position, and provides a new idea for rotor-stator interference to guide the innovation of dishwasher.
    Type of Medium: Online Resource
    ISSN: 1875-9203 , 1070-9622
    URL: Article
    DOI: 10.1155/2022/9349432
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2022
    detail.hit.zdb_id: 2070162-7
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  • 5
    Online Resource
    Online Resource
    Relationship between Endplate Defects, Modic Change, Disc Degeneration, and Facet Joint Degeneration in Patients with Low Back Pain
    Hindawi Limited ; 2019
    In:  BioMed Research International Vol. 2019 ( 2019-07-11), p. 1-9
    Details
    In: BioMed Research International, Hindawi Limited, Vol. 2019 ( 2019-07-11), p. 1-9
    Abstract: Purpose . The endplate defects (EDs), Modic changes (MCs), disc degeneration (DD), facet orientation (FO), and facet tropism (FT) were demonstrated to be related to the low back pain (LBP). The aim of this study was to investigate possible correlations between them. Methods . 75 patients were reviewed to evaluate the degenerative change in vertebral bodies (EDs and MCs), intervertebral discs (DD), and facet joint degeneration (FO and FT). All patients were categorized into four groups based on the grade of EDs. Clinical outcomes were evaluated with the visual analog scale (VAS) and Oswestry disability index (ODI) before and after surgery. Results . There was no difference between the four groups in baseline characteristics except for gender and weight. FT is positively correlated with FO. The same rule exists between EDs, the size of MCs II, FO (left) and FO (right), and VAS and ODI. The grade of EDs is positively correlated with the grade of DD. L4-L5 can bear more load than other levels; thus, the grade of EDs is higher than that of other lumbar levels. The preoperative LBP was relieved in all groups in varying degrees. The change of pain and dysfunction is inversely proportional to the grade of EDs in the general trend. Conclusion . The relationship between weight, gender, and disc degeneration provided a mechanism by which increasing weight can predispose to DD. Different grades of EDs had different effects on patients with LBP. There was a significant correlation between EDs, MCs II, DD, FT, and FO.
    Type of Medium: Online Resource
    ISSN: 2314-6133 , 2314-6141
    URL: Article
    DOI: 10.1155/2019/9369853
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2019
    detail.hit.zdb_id: 2698540-8
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