GLORIA

GEOMAR Library Ocean Research Information Access

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Georg Thieme Verlag KG  (2)
  • 1
    In: Journal of Pediatric Neurology, Georg Thieme Verlag KG, Vol. 20, No. 01 ( 2022-02), p. 071-074
    Abstract: Many pediatric medical protocols or drug posology like biantiplatelet therapy are extrapolated from adult care. This association could be indicated in specific pediatric situations such as ischemic stroke, some cardiac conditions, or to control post stent thrombosis/stenosis. If acetylsalicylic acid is commonly used, few data are available about optimal management of clopidogrel in children. We describe the case of a 7-year-old girl admitted to pediatric intensive care unit who undergoes a transitory hemiparesis after a bicycle accident. Brain magnetic resonance imaging reveals a subarachnoid hemorrhage and a wide right Sylvian arachnoid cyst. Hemorrhage predominated at the level of the optochiasmatic cistern, close to the right internal carotid artery. At the same level, angiography revealed a small aneurysm of the internal carotid artery supposed to be a postfalse traumatic aneurysm. The deployment treated this aneurysm of a flow diverter. The treatment was performed under continuous systemic heparin therapy associated with intravenous acetylsalicylic acid, and Clopidogrel was administered immediately after the procedure. An oral bi antiplatelet treatment was initiated the day 2 with acetylsalicylic acid and clopidogrel (1 mg/kg/day). To monitor clopidogrel posology, a vasodilator-stimulated phosphoprotein [VASP]) was performed. The final VASP assay result was 20% for a clopidogrel posology at 0.5 mg/kg/day. Blood pressure and neurological examination were normal during all the hospitalization. VASP assay can be used in children to define the optimal posology of clopidogrel. Further studies are required to determine an optimal initial posology.
    Type of Medium: Online Resource
    ISSN: 1304-2580 , 1875-9041
    Language: English
    Publisher: Georg Thieme Verlag KG
    Publication Date: 2022
    detail.hit.zdb_id: 2130673-4
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 2
    Online Resource
    Online Resource
    Georg Thieme Verlag KG ; 2014
    In:  Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery Vol. 33, No. 03 ( 2014-09), p. 176-185
    In: Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery, Georg Thieme Verlag KG, Vol. 33, No. 03 ( 2014-09), p. 176-185
    Abstract: Objective: To describe and analyze five cases of symptomatic intracranial spontaneous cortical dissections and a review of the literature relating to this disorder. Method: Retrospective analysis of patients undergoing investigation for intracranial hemorrhage. Data were compiled from the medical file and PACS of the Nancy University Hospital. Results: Of 350 patients who underwent investigation for spontaneous intracranial hemorrhage, five patients (four women) harbored intracranial distal dissections, with no evidence of infection, trauma, arterial hypertension, vasculitis. The patients age ranged from 35 to 77 years (mean age 50.8 years). No patient presented with a poor grade SAH (Hunt and Hess grade IV or V). All patients presented with headache. The localization of the vessel abnormality was equally distributed between the anterior and posterior circulation. All patients, except one, harbored an aneurysmal sac angiographically detectable. Conclusion: Dissecting aneurysms of the intracranial distal/cortical arteries are exceedingly rare vascular lesions that produce neurologic symptoms related to their topography and hemorrhagic or ischemic nature. In the aneurysmal forms, the treatment in an urgent fashion may be considered if we consider the risk of re-hemorrhage. The first-choice treatment is coil occlusion of the involved artery at the level of the dissection.
    Type of Medium: Online Resource
    ISSN: 0103-5355 , 2359-5922
    Language: English
    Publisher: Georg Thieme Verlag KG
    Publication Date: 2014
    detail.hit.zdb_id: 2824608-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...