In:
Synthesis, Georg Thieme Verlag KG, Vol. 49, No. 17 ( 2017-09), p. 3863-3873
Abstract:
A diversified synthesis of 2-(4-oxo[1,2,3]triazolo-[1,5-a] quinoxalin-5(4H)-yl)acetamide derivatives is demonstrated. The protocol employs a Ugi four-component reaction for the assembling of N-(2-haloaryl)propynamide intermediates and followed by a copper-catalyzed tandem reaction of the synthetic N-(2-haloaryl)propynamides with sodium azide. Such a method provides rapid access to structurally varied and complex fused tricyclic scaffolds through readily available starting materials.
Type of Medium:
Online Resource
ISSN:
0039-7881
,
1437-210X
DOI:
10.1055/s-0036-1590791
Language:
English
Publisher:
Georg Thieme Verlag KG
Publication Date:
2017
detail.hit.zdb_id:
204080-3
detail.hit.zdb_id:
2033062-5
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