In:
Journal of Clinical Pathology, BMJ, Vol. 75, No. 2 ( 2022-02), p. 112-116
Abstract:
The number of clinical autopsies decreases while the rate of missed relevant diagnoses is known to be 2%–20%. In this study, we focused on postmortem examinations of patients after transplantation of solid organs. Methods A total of 122 cases were assessed for this study. Transplant organs included liver (LiTx; n=42/122, 34%), heart (n=8/122, 7%), lungs (n=32/122, 26%), kidney (KTx; n=38/122, 31%) and KTx+LiTx (n=2/122, 2%). Results The most frequent autopsy-verified causes of death were cardiac or respiratory failure (together n=85/122, 70%). The frequency of malignant tumours that were identified at autopsy was 5% (n=6/122). In 3% (n=4/122) of cases, Goldman class I discrepancies between clinical diagnosis and autopsy findings were identified. Conclusions The rate of missed relevant diagnoses might be relatively low, but these cases nevertheless refute the contention that modern diagnostic techniques negate the need for autopsies in patients who died after transplantation.
Type of Medium:
Online Resource
ISSN:
0021-9746
,
1472-4146
DOI:
10.1136/jclinpath-2020-207080
Language:
English
Publisher:
BMJ
Publication Date:
2022
detail.hit.zdb_id:
2028928-5
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