In:
Annual Review of Genomics and Human Genetics, Annual Reviews, Vol. 1, No. 1 ( 2000-09), p. 387-407
Abstract:
This review discusses the prospects for understanding the genetic basis of complex traits in humans. We take the view that work done on Drosophila melanogaster can serve as a model for understanding complex traits in humans, and the literature on this model system, as well as on humans, is reviewed. The prospects for success in understanding the genetic basis of complex traits depend, in part, on the nature of the forces acting on genetic variation. We suggest that different experimental approaches should be undertaken for traits caused by common genetic variants versus those arising from rare genetic variants.
Type of Medium:
Online Resource
ISSN:
1527-8204
,
1545-293X
DOI:
10.1146/genom.2000.1.issue-1
DOI:
10.1146/annurev.genom.1.1.387
Language:
English
Publisher:
Annual Reviews
Publication Date:
2000
detail.hit.zdb_id:
2033916-1
SSG:
12
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