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  • 1
    Online Resource
    Online Resource
    Berlin : Duncker & Humblot
    Keywords: Electronic books
    Type of Medium: Online Resource
    Pages: 1 online resource (103 pages)
    Edition: 1st ed.
    ISBN: 9783428427581
    Series Statement: Schriften des Rheinisch-Westfälischen Instituts für Wirtschaftsforschung
    Language: German
    Note: Description based on publisher supplied metadata and other sources
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  • 2
    Publication Date: 2013-01-05
    Description: Background: Morbidity and mortality related to Prescription Opioid Analgesics (POA) have been rising sharply in North America. Non-Medical Prescription Opioid Use (NMPOU) in the general population is a key indicator of POA-related harm, yet the role of survey question design for best NMPOU prevalence estimates is unclear, and existing NMPOU survey data for Canada are limited. Methods: We tested the impact of different NMPOU question items by comparing an item in the 2008 and 2009 (N = 2,017) samples of the CAMH Monitor surveys -- an Ontario adult general population survey -- with a newly developed item used in the 2010 (N = 2,015) sample of the CAMH Monitor survey. To control for a potential difference in the population demographics between surveys, we adjusted for gender, age, region, income, prescription opioid use, cigarette smoking, weekly binge drinking, cannabis use in the past three months, and psychological distress in our analyses. Results: The prevalence of NMPOU as measured by the 2008 and 2009 CAMH monitor (2.0% [95% CI: 1.2% to 2.8%]) was significantly different when compared to the prevalence of NMPOU as measured by the 2010 CAMH monitor (7.7% [95% CI: 6.3% to 9.2%]) (p 〈 0.001). This difference was also found when stratifying our analysis by sex (p 〈 0.001) and when adjusting for all potential confounding covariates. Conclusion: It is highly unlikely that the multifold NMPOU prevalence differences observed from the different survey items reflect an actual increase of NMPOU or changes in NMPOU determinants, but rather point to measurement effects. It appears that we currently do not have accurate estimates of NMPOU in the Canadian general population, even though these are needed to guide and implement targeted interventions. Given the current substantial morbidity and mortality impact of NMPOU, there is an urgent need to systematically develop, validate and standardize NMPOU items for future general population surveys in Canada.
    Electronic ISSN: 1471-244X
    Topics: Medicine
    Published by BioMed Central
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  • 3
    Publication Date: 2022-05-25
    Description: Author Posting. © American Meteorological Society, 2017. This article is posted here by permission of American Meteorological Society for personal use, not for redistribution. The definitive version was published in Bulletin of the American Meteorological Society 98 (2017): 737-752, doi:10.1175/BAMS-D-16-0057.1.
    Description: For decades oceanographers have understood the Atlantic meridional overturning circulation (AMOC) to be primarily driven by changes in the production of deep-water formation in the subpolar and subarctic North Atlantic. Indeed, current Intergovernmental Panel on Climate Change (IPCC) projections of an AMOC slowdown in the twenty-first century based on climate models are attributed to the inhibition of deep convection in the North Atlantic. However, observational evidence for this linkage has been elusive: there has been no clear demonstration of AMOC variability in response to changes in deep-water formation. The motivation for understanding this linkage is compelling, since the overturning circulation has been shown to sequester heat and anthropogenic carbon in the deep ocean. Furthermore, AMOC variability is expected to impact this sequestration as well as have consequences for regional and global climates through its effect on the poleward transport of warm water. Motivated by the need for a mechanistic understanding of the AMOC, an international community has assembled an observing system, Overturning in the Subpolar North Atlantic Program (OSNAP), to provide a continuous record of the transbasin fluxes of heat, mass, and freshwater, and to link that record to convective activity and water mass transformation at high latitudes. OSNAP, in conjunction with the Rapid Climate Change–Meridional Overturning Circulation and Heatflux Array (RAPID–MOCHA) at 26°N and other observational elements, will provide a comprehensive measure of the three-dimensional AMOC and an understanding of what drives its variability. The OSNAP observing system was fully deployed in the summer of 2014, and the first OSNAP data products are expected in the fall of 2017.
    Description: The authors gratefully acknowledge financial support from the U.S. National Science Foundation (NSF; OCE-1259102, OCE-1259103, OCE-1259618, OCE-1258823, OCE-1259210, OCE-1259398, OCE-0136215, and OCE-1005697); the U.S. National Aeronautics and Space Administration (NASA); the U.S. National Oceanic and Atmospheric Administration (NOAA); the WHOI Ocean and Climate Change Institute (OCCI), the WHOI Independent Research and Development (IRD) Program, and the WHOI Postdoctoral Scholar Program; the U.K. Natural Environment Research Council (NERC; NE/K010875/1, NE/K010700/1, R8-H12-85, FASTNEt NE/I030224/1, NE/K010972/1, NE/K012932/1, and NE/M018024/1); the European Union Seventh Framework Programme (NACLIM project, 308299 and 610055); the German Federal Ministry and Education German Research RACE Program; the Natural Sciences and Engineering Research Council of Canada (NSERC; RGPIN 227438-09, RGPIN 04357, and RG-PCC 433898); Fisheries and Oceans Canada; the National Natural Science Foundation of China (NSFC; 41521091, U1406401); the Fundamental Research Funds for the Central Universities of China; the French Research Institute for Exploitation of the Sea (IFREMER); the French National Center for Scientific Research (CNRS); the French National Institute for Earth Sciences and Astronomy (INSU); the French national program LEFE; and the French Oceanographic Fleet (TGIR FOF).
    Description: 2017-10-24
    Repository Name: Woods Hole Open Access Server
    Type: Article
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