In:
Malawi Medical Journal, African Journals Online (AJOL), Vol. 34, No. 1 ( 2022-04-01), p. 25-30
Abstract:
BackgroundThere is a growing interest in medicinal plants in recent years due to their many therapeutic benefits and low side effects. Among the medicinal plants is the African Adansonia digitata (baobab) that has edible fruit. In the current study, the effect of A. digitata juice consumption on the lipid profile was investigated. In addition, inhibition of the oxidation of low-density lipoprotein cholesterol (LDL-C) in-vitro by A. digitata essential oil (EO) was also investigated. MethodsIn this cohort study, a total of 70 subjects of A. digitata users (AD group, 42 male and 28 female) and 70 non A. digitata users (Non-AD group, 44 male and 26 female) were recruited to participate in this study. We evaluated lipid profile, HbA1c, liver/kidney functions, and phytosterol contents in fasting blood samples of all participants.ResultsThe present findings illustrated significantly lower levels of total cholesterol, triglycerides, and LDL in the AD group compared to Non-AD (p 〈 0.01). In addition, essential oil of A. digitata inhibited LDL oxidation in-vitro as shown by the significant decreases in the formation of malonaldehyde (MDA), protein carbonyl (PC), and lipid hydroperoxide (LHP) (P 〈 0.05). No significant changes in fasting blood glucose, HbA1c, HDL, kidney function, and liver function enzymes between the two groups were detected (P 〉 0.05). ConclusionThe juice of A. digitata has hypolipidemic and antioxidative effects and might be beneficial for the management of lipid levels in the body.
Type of Medium:
Online Resource
ISSN:
1995-7262
,
1995-7262
Language:
Unknown
Publisher:
African Journals Online (AJOL)
Publication Date:
2022
detail.hit.zdb_id:
2491952-4
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