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  • 1980-1984  (2)
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Publisher
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Year
  • 1
    Electronic Resource
    Electronic Resource
    Effects ofd-penicillamine on a model of oxygen-derived free radical mediated tissue damage (1984)
    Springer
    Inflammation research 14 (1984), S. 283-290 
    Details
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In vitro studies indicate thatd-penicillamine can affect the depolymerization of hyaluronate in aqueous media (induced primarily by the hydroxyl radical) in several ways. These include: (1) Protecting the hyaluronate by quenching oxygen-derived free radicals (ODFR). Hydrated cupric ions alone and copper(II)-penicillamine complexes were equipotent in quenching ODFR but more potent thand-penicillamine alone. (2) Initiating hyaluronate degradation by (a) directly reducting inert Fe(III) to reactive Fe(II) (which may autoxidize to produce hydroxyl radicals), a property shared with other thiols, and (b) forming reactive iron complexes that catalyse the formation of hydroxyl radicals from superoxide and hydrogen peroxide.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01966654
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Novel application of aniline blue (1984)
    Springer
    Histochemistry and cell biology 81 (1984), S. 93-98 
    Details
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The present study shows that aniline blue can be used as a fluorescent stain for glycogen. The dye is also helpful in tracing pathological and autolytic changes in lysosomes, mitochondria, erythrocytes and nuclei, and it can also be used for demonstrating bacteria in tissue sections and smears. The techniques used are simple, rapid and inexpensive. Spectrophotometric studies on aniline blue solutions have shown that aniline blue fluorescence was enhanced by the addition of certain proteins, or of glycogen to the dye solution. In case of albumen which has the maximum effect, enhancement is dependent upon the albumen-dye ratio. The mechanism of staining is mainly due to self quenching, but there is also an evidence of the presence of hydrophobic reaction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00495407
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    Paper (German National Licenses)
    Fulltext
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