ISSN:
1432-2013
Keywords:
Hypertension
;
Deoxicorticosterone
;
Sodium chloride
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Changes in blood pressure and body fluids volume caused by an acute saline load were studied in 6 normal and 7 DOCA-salt early hypertensive rats having normal inulin space and plasma volume. After loading, blood pressure increased in the normal group (+23 mm Hg) and fell (−17 mm Hg) in the DOCA-salt group. Expansion of extracellular fluid volume was similar in both groups but expansion of plasma volume was twice as high in the DOCA-salt than in the normal group. The results are compatible with an inhibition of a volume-sensitive vasopressor mechanism possibly involving vasopressin.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00658272
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