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  • 1
    Online Resource
    Online Resource
    St. Louis :Elsevier Science & Technology,
    Keywords: Biotransformation (Metabolism). ; Enzymes -- Biotechnology. ; Organic compounds -- Synthesis. ; Electronic books.
    Description / Table of Contents: This volume is designed for chemists working in an organic chemistry laboratory and for all scientists with an interest in biotransformations. It summarizes the important aspects of work in the burgeoning field of biotransformations, th...[missing text].
    Type of Medium: Online Resource
    Pages: 1 online resource (281 pages)
    Edition: 1st ed.
    ISBN: 9780080984476
    DDC: 547.2
    Language: English
    Note: Front Cover -- Biotransformations in Preparative Organic Chemistry: The Use of Isolated Enzymes and Whole Cell Systems in Synthesis -- Copyright Page -- Table of Contents -- Foreword -- Preface -- References -- Chapter 1. Biotransformations-Introduction and Background Information -- 1.1 The Past: A Selection of the Important, Well-established Uses of Whole-cell and Enzyme catalysed Biotransformations -- 1.2 The Present -- 1.3 The Future: Prospects for Biotransformations -- References -- Chapter 2. Hydrolysis and Condensation Reactions -- 2.1 Cleavage and Formation of Carboxylic Acid Ester Bonds -- 2.2 Cleavage and Formation of the Amide Bond -- 2.3 Cleavage and Formation of Phosphate Esters -- 2.4 Hydrolysis of Epoxides -- 2.5 Hydrolysis of Nitriles -- References -- Chapter 3. Enzyme Catalysed Reduction Reactions -- 3.1 Reduction of Aldehydes and Ketones -- 3.2 Reduction of Carbon-Carbon Double Bonds -- References -- Chapter 4. Oxidation Reactions -- 4.1 The Oxidation of Alcohols and Aldehydes -- 4.2 Baeyer-Villiger Type Oxidation of a Carbonyl Compound -- 4.3 Hydroxylation -- 4.4 Oxidation at Sulphur -- 4.5 Epoxidation -- References -- Chapter 5. Other Biotransformations -- 5.1 Reactions Involving the Formation of a Carbon-Carbon Bond -- 5.2 Carbohydrate, Nucleoside and Nucleotide Chemistry -- 5.3 Preparation and Reactions of Amino Acids -- 5.4 Formation of Halohydrins and Dihalides -- 5.5 O- and N-Dealkylation -- References -- Index of Species, Compounds and Methods.
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 15 (1985), S. 0 
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A new indoor nasal allergen challenge system has been developed which allows subjects with hay fever to be exposed to pre-determined concentration of grass pollen grains in the immediate environment. Thirteen subjects were exposed during the winter months to an atmosphere containing approximately 1000 grains/m3 for 30 min. No changes in nasal airway patency or symptoms of nasal congestion were recorded. It was necessary to increase the pollen concentration to approximately 9000 and 35 000 grains/m3 in two subjects and six subjects respectively, before a positive response was recorded. This response was reproducible in all subjects. Administration of intra-nasal sodium cromoglycate before exposure significantly inhibited the decrease in nasal airway patency and when administered 1 min before exposure totally abolished symptoms of nasal congestion. This new challenge system may therefore be used as an in vivo screen to assess the potential therapeutic value of drugs in hay fever under controlled conditions.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Meteorology and atmospheric physics 41 (1989), S. 147-156 
    ISSN: 1436-5065
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Summary A study is undertaken of the semi-geostrophic flow of shallow water incident tangentially upon a sharp leading edged, slender, orographic feature. The nature of the response is shown to depend upon the Froude number of the upstream flow and upon the orographic shape. In particular it is deduced that the orographically split flow has a laterally asymmetric response, and that for sub-critical upstream settings a jet can develop on one particular side of the orography. Features of an easterly low-level jet observed on the Alpine northside during the ALPEX project are compared with the theory.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Zeitschrift für angewandte Mathematik und Physik 36 (1985), S. 495-498 
    ISSN: 1420-9039
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Geo-marine letters 6 (1987), S. 181-191 
    ISSN: 1432-1157
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract The floor of the western Solomon Sea (for new bathymetric map see inside back cover of this issue) is dominated by the arched and ridged basement of the Solomon Sea Basin, the partly-sediment-filled New Britain Trench, and a more completely filled trench, the Trobriand Trough. There is a deep basin where the trenches join (149° Embayment), and a silled basin west of the New Britain Trench (Finsch Deep). Submarine canyons descend from the west and south to the 149° Embayment. Abyssal fans and plains are structurally defined and locally disturbed by young faults. Probable submerged pinnacle reefs stand in water depths as great as 1,200 m.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-1157
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract The anticlinal nappe which forms the Huon Peninsula and adjacent ranges extends offshore as the Huon Ridge. The frontal thrust of the nappe is the Ramu-Markham Fault (onshore) and a deformation front along the line of the Markham Canyon (offshore). The timing and geometry of the Finisterre arc-continent collision is controversial, and the origin of the Finsch Deep is unresolved.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-1157
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract The western Solomon Sea is bounded by the Paleogene collision complex of the Papuan Peninsula to the south, and land masses constructed by Cainozoic volcanism to the north and cast. Oblique collision of two trenches in the western Solomon Sea, and concomitant collision of upper plates, have produced structural complexities that may include the local doubling of crustal thickness, coincident with a strong negative gravity anomaly west of 149°E. Lateral flexing of the subducted plate in the New Britain Trench may have caused flexure of the upper plate; this flexure is expressed in the gravity field, faults, dip-slopes, exposure of basement, and alignment of volcanoes.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Geo-marine letters 6 (1987), S. 193-202 
    ISSN: 1432-1157
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract Volcanic rocks collected from the Solomon Sea Basin are mostly ferrobasalt lavas similar to evolved MORB; an exception is a single sample of basaltic crystal tuff invaded by later basalt. The rocks contain labradorite, aluminous diopsidic augite, and titanomagnetite, with olivine and pigconite in the more vitrophyric samples, and segregation vesicles in some. Cobbles dredged from Gudaraba Canyon, south of the Solomon Sea Basin, include both MORB-like glassy lava and K-metasomatised basalt and andesite(?). Two small pieces of volcanic glass from the southern Bismarck Sea are more primitive MOR-type basalts.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Geo-marine letters 7 (1987), S. 129-134 
    ISSN: 1432-1157
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract A south-dipping Subduction system which underlies the Trobriand Trough and 149° Embayment, on the southern margin of the Solomon Sea, is active or was recently active. Oceanic basement is overlain by 2.5 s, two-way travel time (TWTT), of sediment that shows at least two stages of deformation: early thrusts (inner wall) and normal faults (outer wall), and later normal faults that have elevated the outer trench margin. Thrust anticlines and slope basins are developed on the inner wall. The floor of the Solomon Sea Basin arches upward between the Trobriand Trough and the New Britain Trench to form isolated peaks and ridges in the east (152° Peaks) and an east-west Central Ridge in the west. Structures in the subduction system, and in the Solomon Sea Basin, plunge westward towards the point of collision with the New Britain Trench.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Geo-marine letters 7 (1987), S. 135-142 
    ISSN: 1432-1157
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract The western New Britain Trench contains relatively thin sediment fill in the east, compared to the west where a sequence of thick turbidites is ponded behind a basement high in the trench axis, The trench trends toward Huon Gulf, but intersects the Trobriand Trench at an acute angle at the 149° Embayment, where both trenches end. Seismic structure west of the trench is incoherent, related to incipient collision of the Indian-Australia Plate and the South Bismarck Plate. The collision suture is marked by the Markham Canyon, continuous in its upper reaches with the Ramu-Markham Fault Zone on shore.
    Type of Medium: Electronic Resource
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