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Airway management during an EXIT procedure for a fetus with dysgnathia complex (2004)

Baker, Paul A ; Aftimos, Salim ; Anderson, Brian J

Oxford, UK : Blackwell Publishing Ltd

Pediatric anesthesia 14 (2004), S. 0

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ISSN: 1460-9592

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: Nonsyndromal dysgnathia is a rare disorder with a probable genetic basis characterized by a hypoplastic or absent mandible (agnathia), microstomia, microglossia, and ear anomalies secondary to a defect in the ventral portion of the first branchial arch caused by defective neural crest migration or proliferation. Dysgnathic newborn infants often suffer fatal respiratory failure from airway obstruction. Nineteen children with isolated dysgnathia complex are described in the literature – six were stillborn, eight died shortly after birth, and only five survived infancy. All survivors required tracheostomy to maintain an airway. It is difficult to intubate the trachea of these children and early airway management planning is important. We report a neonate who presented with a prenatal ultrasound diagnosis of severe micrognathia, polyhydramnios and a family history of severe micrognathia. Airway management was achieved with fiberoptic intubation through a laryngeal mask airway (LMATM) during an ex utero intrapartum treatment procedure. Fiberoptic intubation was hampered by copious amounts of amniotic fluid. This child and her sibling are the first two siblings with isolated dysgnathia complex to have survived infancy and provide further support for a genetic basis to this condition.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1460-9592.2004.01284.x

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Tropical climate changes at millennial and orbital timescales on the Bolivian Altiplano (2001)

Rigsby, Catherine A. ; Seltzer, Geoffrey O. ; Fritz, Sherilyn C. ; [et al.]

[s.l.] : Macmillian Magazines Ltd.

Nature 409 (2001), S. 698-701

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ISSN: 1476-4687

Source: Nature Archives 1869 - 2009

Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics

Notes: [Auszug] Tropical South America is one of the three main centres of the global, zonal overturning circulation of the equatorial atmosphere (generally termed the ‘Walker’ circulation). Although this area plays a key role in global climate cycles, little is known about South American climate ...