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  • Cambridge University Press (CUP)  (10)
  • 2000-2004  (10)
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  • Cambridge University Press (CUP)  (10)
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  • 2000-2004  (10)
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Subjects(RVK)
  • 1
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2001
    In:  Reviews in Clinical Gerontology Vol. 11, No. 3 ( 2001-08), p. 209-214
    In: Reviews in Clinical Gerontology, Cambridge University Press (CUP), Vol. 11, No. 3 ( 2001-08), p. 209-214
    Abstract: Research shows that approximately one in three people over the age of 65 years falls in any one year, with approximately one in three falling again in the following year. Prevalence of falls also increases with age, and women are more likely to fall than men. However, in advanced old age the ratio of men and women fallers reaches equal proportions.
    Type of Medium: Online Resource
    ISSN: 0959-2598 , 1469-9036
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2001
    detail.hit.zdb_id: 2000041-8
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  • 2
    In: British Journal of Nutrition, Cambridge University Press (CUP), Vol. 90, No. 6 ( 2003-12), p. 1071-1080
    Abstract: The effects of altering the type of n -3 polyunsaturated fatty acid (PUFA) in the mouse diet on the ability of monocytes and neutrophils to perform phagocytosis were investigated. Male weanling mice were fed for 7 d on one of nine diets which contained 178 g lipid/kg and which differed in the type of n -3 PUFA and in the position of these in dietary triacylglycerol (TAG). The control diet contained 4·4 g α-linolenic acid/100 g total fatty acids. In the other diets, eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA) replaced a proportion (50 or 100 %) of the α-linolenic acid, and were in the sn -2 or the sn -1(3) position of dietary TAG. There were significant increases in the content of n -3 PUFA in spleen-cell phospholipids when EPA or DHA was fed. These increases were largely independent of the position of EPA or DHA in dietary TAG except when EPA was fed at the highest level, when the incorporation was greater when it was fed in the sn -2 than in the sn -1(3) position. There was no significant effect of dietary DHA on monocyte or neutrophil phagocytic activity. Dietary EPA dose-dependently decreased the number of monocytes and neutrophils performing phagocytosis. However, when EPA was fed in the sn -2 position, the ability of active monocytes or neutrophils to engulf bacteria was increased in a dose-dependent fashion. This did not occur when EPA was fed in the sn -1(3) position. Thus, there appears to be an influence of the position of EPA, but not of DHA, in dietary TAG on its incorporation into cell phospholipids and on the activity of phagocytic cells.
    Type of Medium: Online Resource
    ISSN: 0007-1145 , 1475-2662
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2003
    detail.hit.zdb_id: 2016047-1
    SSG: 12
    SSG: 21
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  • 3
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2003
    In:  Econometric Theory Vol. 19, No. 05 ( 2003-10)
    In: Econometric Theory, Cambridge University Press (CUP), Vol. 19, No. 05 ( 2003-10)
    Type of Medium: Online Resource
    ISSN: 0266-4666 , 1469-4360
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2003
    detail.hit.zdb_id: 1501041-7
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  • 4
    In: Quaternary Research, Cambridge University Press (CUP), Vol. 62, No. 3 ( 2004-11), p. 243-255
    Abstract: Although the dramatic climate disruptions of the last glacial period have received considerable attention, relatively little has been directed toward climate variability in the Holocene (11,500 cal yr B.P. to the present). Examination of ?50 globally distributed paleoclimate records reveals as many as six periods of significant rapid climate change during the time periods 9000"8000, 6000"5000, 4200"3800, 3500"2500, 1200"1000, and 600"150 cal yr B.P. Most of the climate change events in these globally distributed records are characterized by polar cooling, tropical aridity, and major atmospheric circulation changes, although in the most recent interval (600"150 cal yr B.P.), polar cooling was accompanied by increased moisture in some parts of the tropics. Several intervals coincide with major disruptions of civilization, illustrating the human significance of Holocene climate variability.
    Type of Medium: Online Resource
    ISSN: 0033-5894 , 1096-0287
    RVK:
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2004
    detail.hit.zdb_id: 1471589-2
    detail.hit.zdb_id: 205711-6
    SSG: 13
    SSG: 14
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  • 5
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2000
    In:  Journal of Paleontology Vol. 74, No. 1 ( 2000-01), p. 1-6
    In: Journal of Paleontology, Cambridge University Press (CUP), Vol. 74, No. 1 ( 2000-01), p. 1-6
    Type of Medium: Online Resource
    ISSN: 0022-3360 , 1937-2337
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2000
    detail.hit.zdb_id: 219113-1
    detail.hit.zdb_id: 2047591-3
    SSG: 13
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  • 6
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2000
    In:  Journal of Paleontology Vol. 74, No. 1 ( 2000-01), p. 1-6
    In: Journal of Paleontology, Cambridge University Press (CUP), Vol. 74, No. 1 ( 2000-01), p. 1-6
    Abstract: The distinctive cheilostome bryozoan Stictostega durhami Shaw, 1967, from the Upper Campanian Ozan Formation of Arkansas, is redescribed and its relationships are reconsidered. Originally interpreted as a hippothoid ascophoran, the presence of a cryptocystal frontal shield and other characters suggest that it is a coilostegan anascan. Pores in the frontal shield are inferred to have served for the passage of parietal muscles (or their ligaments), which operated on the frontal membrane to raise hydrostatic pressure and protrude the lophophore in the same way as recently demonstrated in living Macropora. Stictostega is provisionally interpreted as a stem-group macroporid.
    Type of Medium: Online Resource
    ISSN: 0022-3360 , 1937-2337
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2000
    detail.hit.zdb_id: 219113-1
    detail.hit.zdb_id: 2047591-3
    SSG: 13
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  • 7
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2002
    In:  Weed Technology Vol. 16, No. 4 ( 2002-10), p. 707-711
    In: Weed Technology, Cambridge University Press (CUP), Vol. 16, No. 4 ( 2002-10), p. 707-711
    Type of Medium: Online Resource
    ISSN: 0890-037X , 1550-2740
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2002
    detail.hit.zdb_id: 2119100-1
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  • 8
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2000
    In:  Cardiology in the Young Vol. 10, No. 6 ( 2000-11), p. 618-620
    In: Cardiology in the Young, Cambridge University Press (CUP), Vol. 10, No. 6 ( 2000-11), p. 618-620
    Abstract: Deletions of chromosome 22q11 are common in patients with tetralogy of Fallot, and in those with absent pulmonary valve syndrome. In this report, we describe a pair of siblings with absent pulmonary valve syndrome, neither of whom had deletions of chromosome 22q11. The finding of familial absent pulmonary valve syndrome without deletion of 22q11 in our patients suggests an alternative genetic basis for this rare condition.
    Type of Medium: Online Resource
    ISSN: 1047-9511 , 1467-1107
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2000
    detail.hit.zdb_id: 2060876-7
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  • 9
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2000
    In:  Cardiology in the Young Vol. 10, No. 3 ( 2000-05), p. 212-219
    In: Cardiology in the Young, Cambridge University Press (CUP), Vol. 10, No. 3 ( 2000-05), p. 212-219
    Abstract: Abnormalities of brachiocephalic arterial branching and arch laterality are common in patients with a cervical aortic arch. In addition, structural anomalies of the arch such as obstruction, aneurysms, and tortuosity are found in a significant number of cases. Methods Between 1990 and 1998, 6 patients underwent surgery for an obstructed right cervical arch. A significant obstruction was present at the transverse or distal arch in all patients, and was recurrent after previous repair in 2. In 1 patient, there was also a multi-lobed aneurysm of the aortic segment contiguous to the obstruction, and in 2 there was marked tortuosity of the arch. In all cases, the order of origin of the head and neck vessels was abnormal, and obstruction of 1 or more brachiocephalic vessels was found in 3. A vascular ring was present in all patients, with a right aortic arch and aberrant left subclavian artery in 4 patients and a double aortic arch with a dominant right cervical arch in 2. The descending aorta was circumflex (left-sided) in 3 patients. Three patients were repaired through a standard right posterolateral thoracotomy, and 3 through a median sternotomy. Patch augmentation aortoplasty was used in 2 patients, a tube graft from the ascending to descending aorta in 2, end to side anastomosis of the descending aorta to the proximal arch in 1, and direct anastomosis to reconstruct an atretic left-sided component of a double arch in 1. Results Repair was successful in all cases, with no perioperative complications. At follow-up ranging from 1 to 9 years, all patients were alive and well, with no recurrence of arch obstruction or other significant complications. Fluorescent in situ hybridization revealed microdeletion of chromosome 22q 11 in 1 patient (not performed in the others). Conclusions Structural anomalies of the arch are relatively common in patients with a cervical aortic arch. Such abnormalities may be the result of hemodynamic conditions and/or abnormal vascular tissue related either to the cervical position of the arch or its embryologic precursors. Given the highly variable anatomy of patients with a complicated cervical aortic arch, surgical considerations will vary in kind.
    Type of Medium: Online Resource
    ISSN: 1047-9511 , 1467-1107
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2000
    detail.hit.zdb_id: 2060876-7
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  • 10
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2002
    In:  British Journal of Nutrition Vol. 87, No. 6 ( 2002-06), p. 587-593
    In: British Journal of Nutrition, Cambridge University Press (CUP), Vol. 87, No. 6 ( 2002-06), p. 587-593
    Abstract: Exogenous insulin-like growth factor (IGF)-I has been shown to increase growth rate in neonatal pigs while an analogue of IGF-I, long arginine (LR3) IGF-I, has been shown to be more potent than IGF-I in the rat. Therefore, two studies were conducted to determine whether IGF-I and LR3IGF-I increase growth in the artificially-reared neonatal pig. Expt 1 involved forty-two (2 kg initial weight) pigs infused with either control, IGF-I (2, 4 or 8 μg/h) or LR3IGF-I (2, 4 or 8 μg/h) infusions for 8 d. Pigs were weighed and then offered 1·7 MJ (gross energy) milk replacer/kg 0·75 per d. Expt 2 involved eighteen pigs (2 kg initial weight) treated with control saline, IGF-I (8 μg/h) or LR3IGF-I (8 μg/h) infusions. After 9 d an additional pump was inserted to increase the infusion rates of each of the growth factors (16 μg/h) for a further 9 d. Cows' milk was provided ad libitum . In Expt 1 there was no overall effect of growth factors on daily weight gain or slaughter weight. However, milk intake was greater in pigs infused with growth factors (909 v. 867 g/d, P =0·027), with an apparently greater milk intake by the pigs infused with IGF-I compared with LR3IGF-I (920 v. 898 g/d, P =0·12). Infusion of LR3IGF-I decreased plasma IGF-I concentrations, but had no effect on plasma IGF-II concentrations. In Expt 2, neither IGF-I nor LR3IGF-I infusion had any effect upon daily weight gain over the first 9 d of the study. However, over the second 9 d of the study, daily weight gain was increased in LR3IGF-I-infused pigs (457 v. 386 g/d, P 〈 0·01), but not in pigs infused with IGF-I (413 v. 386 g/d, P =0·15). Milk intake was not different during the first 9 d of the study but was significantly greater in pigs infused with growth factors over the second half of the study (3407 v. 2905 g/d, P 〈 0·01). Plasma IGF-binding protein-3 concentrations were highly correlated ( R =0·85) with average daily gain over the 3 d preceding blood sampling. In conclusion, exogenous IGF-I and particularly LR3IGF-I can increase growth rate and milk intake in artificially-reared pigs fed ad libitum but not in limit-fed piglets.
    Type of Medium: Online Resource
    ISSN: 0007-1145 , 1475-2662
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2002
    detail.hit.zdb_id: 2016047-1
    SSG: 12
    SSG: 21
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