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  • 2010-2014  (32)
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  • 1
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    Molecular Basis of PLD Cell Adhesion [Signal Transduction] (2014)
    The American Society for Biochemistry and Molecular Biology (ASBMB)
    Details
    Publication Date: 2014-10-18
    Description: Defining how leukocytes adhere to solid surfaces, such as capillary beds, and the subsequent migration through the extracellular matrix, is a central biological issue. We show here that phospholipase D (PLD) and its enzymatic reaction product, phosphatidic acid (PA), regulate cell adhesion of immune cells (macrophages and neutrophils) to collagen and have defined the underlying molecular mechanism in a spatio-temporal manner that coincides with PLD activity timing. A rapid (t½ = 4 min) and transient activation of the PLD1 isoform occurs upon adhesion, and a slower (t½ = 7.5 min) but prolonged (〉30 min) activation occurs for PLD2. Importantly, PA directly binds to actin-related protein 3 (Arp3) at EC50 = 22 nm, whereas control phosphatidylcholine did not bind. PA-activated Arp3 hastens actin nucleation with a kinetics of t½ = 3 min at 300 nm (compared with controls of no PA, t½ = 5 min). Thus, PLD and PA are intrinsic components of cell adhesion, which reinforce each other in a positive feedback loop and react from cues from their respective solid substrates. In nascent adhesion, PLD1 is key, whereas a sustained adhesion in mature or established focal points is dependent upon PLD2, PA, and Arp3. A prolonged adhesion could effectively counteract the reversible intrinsic nature of this cellular process and constitute a key player in chronic inflammation.
    Print ISSN: 0021-9258
    Electronic ISSN: 1083-351X
    Topics: Biology , Chemistry and Pharmacology
    Published by The American Society for Biochemistry and Molecular Biology (ASBMB)
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  • 2
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    Trachyte from the Roman aqueducts of Padua and Este (north-east Italy): a provenance study based on petrography, chemistry and magnetic susceptibility (2013)
    Schweizerbart
    Details
    Publication Date: 2013-10-04
    Description: This study presents the results of archaeometric analysis of the stones used to build the Roman aqueduct in Padua (northeast Italy), in order to identify the petrography and the quarry/ies of provenance from which the stones were exploited. The combined approach, involving petrographic, geochemical and magnetic susceptibility data, shows that the stones used for building the Roman aqueduct were of volcanic origin, with a trachyte composition, were quarried from two different localities in the Euganean Hills (Mt. Merlo and Mt. Oliveto) and that construction of the aqueducts, particularly of its various segments, both in the present-day city centre of Padua and in the Euganean Hills area, was centralised and managed by a single authority.
    Print ISSN: 0935-1221
    Electronic ISSN: 1617-4011
    Topics: Geosciences
    Published by Schweizerbart
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  • 3
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    Constraining chronology and time-space evolution of Holocene volcanic activity on the Capelo Peninsula (Faial Island, Azores): The paleomagnetic contribution (2014)
    Geological Society of America (GSA)
    Details
    Publication Date: 2014-08-29
    Description: Faial is one of the most volcanically active islands of the Azores Archipelago. Historical eruptions occurred on the Capelo Peninsula (westernmost sector of the island) during A.D. 1672–1673 and more recently in A.D. 1957–1958. The other exposed volcanic products of the peninsula are so far loosely dated within the Holocene. Here, we present a successful attempt to correlate scoria cones and lava flows yielded by the same eruption on the Capelo Peninsula using paleomagnetic data from 31 sites (10 basaltic scoriae, 21 basaltic lava flows). In the investigated products, we recognize at least six prehistoric clusters of volcanic activity, whereas 11 lava sites are correlated with four scoria cones. Dating was conducted by comparing our paleomagnetic directions with relocated Holocene reference curves of the paleosecular variation of the geomagnetic field from France and the UK. We find that the studied volcanic rocks exposed on the Capelo Peninsula are younger than previously believed, being entirely formed in the last 8 k.y., and that the activity intensified over the last 3 k.y. Our study confirms that paleomagnetism is a powerful tool for unraveling the chronology and characteristics of Holocene activity at volcanoes where geochronological age constraints are still lacking.
    Print ISSN: 0016-7606
    Electronic ISSN: 1943-2674
    Topics: Geosciences
    Published by Geological Society of America (GSA)
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  • 4
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    Paleomagnetism and magnetic fabric of the Eastern Cordillera of Colombia: Evidence for oblique convergence and nonrotational reactivation of a Mesozoic intracontinental rift (2014)
    In:  Tectonics
    Details
    Publication Date: 2021-12-13
    Description: We report the paleomagnetic and magnetic fabric results of 58 sites from Cretaceous-Miocene marine and continental strata from the Eastern Cordillera (EC) and the Cucuta zone, at the junction between the Santander Massif and the Merida Andes of Colombia. The EC is an intracontinental doubly vergent range inverting a Triassic to Early Cretaceous rift zone. Twenty-three sites reveal nonsystematic tectonic rotations, including unrotated areas of the EC range with respect to stable South America. Our data show that the EC inverted a NNE oriented rift zone and that the orientation of the Mesozoic rift and the mountain chain roughly correspond. Interestingly, magnetic lineations from anisotropy of magnetic susceptibility analysis do not trend parallel to the chain but rather are oblique to the main orogenic trend. By also considering GPS evidence of a ~1 cm/yr ENE displacement of central western Colombia accommodated by the EC, we suggest that the Miocene-Recent deformation event of this belt arises from ENE oblique convergence reactivating a NNE oriented rift zone. Oblique shortening was likely partitioned into pure dip-slip shear characterizing thick-skinned frontal thrust sheets (well known along both chain fronts) and by range-parallel right-lateral strike-slip faults, which have not been identified yet, but likely exist in the axial part of the EC. Finally, the 35° ± 9° clockwise rotation observed in four post-Miocene magnetically overprinted sites from the Cucuta zone reflects late Cenozoic and ongoing right-lateral strike-slip displacement occurring along faults parallel to the Boconó fault system, possibly connected with the right-lateral faults inferred to exist along the axial part of the EC.
    Language: English
    Type: info:eu-repo/semantics/article
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  • 5
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    A major change in the sedimentation regime in the Crotone Basin (Southern Italy) around 3.7-3.6 Ma (2014)
    Elsevier
    Details
    Publication Date: 2021-05-17
    Description: The Lower Pliocene succession of the Crotone Basin (Calabrian Arc, Southern Italy) is mainly comprised of blue-grey marly clay with good magnetic properties. Here the bio-magnetostratigraphic data indicate a mean sedimentation rate of about 12–15 cm/kyr. Around 3.7–3.6 Ma a major change in the sedimentation regime occurred: the blue-grey hemipelagic marls grade rapidly into silty marls with a significant increase in the terrigenous fraction and with abundant siliceous remains throughout the whole interval. Magnetic properties of these sediments are very poor, but an integrated calcareous plankton biostratigraphy (foraminifera and nannofossils) infers a high average sedimentation rate (about 50–60 cm/kyr). The abrupt onset of this sedimentation regime in the Crotone Basin is contemporaneous with a major unconformity already recognized in the northern sector of the basin, part of amajor reorganization phase in the whole Apenninic–Maghrebid Chain known as “Globorotalia puncticulata event”. Reports of coeval siliceous sediments in other marginal basins of the Apennines (Southern Calabria, Southern and Northern Apennines) suggest that this “siliceous event” might have been regionally extensive, having important palaeoceanographical implications.We infer that the “siliceous event” is characterized by a combined tectonic- and climate-induced change in palaeoceanographic conditions. The tectonic triggering factors may have been linked to two synchronous events in the Tyrrhenian–Apennine system: 1) the shortening event also known as “G. puncticulata event”, and 2) the coeval opening of the Vavilov Basin in the Tyrrhenian Sea which yielded profound influences in terms of physiography and characteristics of the Crotone Basin. The consequent uplift of the Southern Apennines would have increased sediment supply and availability of silica, resulting in eutrophication and enhanced silica preservation. Strong winter mixing and possibly upwelling conditions could have increased primary productivity during heavy isotope stages Gi4, Gi2 and MG8, at the onset of the “siliceous event”. This important event, lasting from ca. 3.6 Ma to ca. 3.2 Ma, would have recorded a peculiar transitional period before further climatic deterioration and more drastic palaeoceanographic changes occurred around 3.1 Ma, leading to cyclic sapropel deposition in the whole of the Mediterranean sea.
    Description: Published
    Description: 398-410
    Description: 1A. Geomagnetismo e Paleomagnetismo
    Description: JCR Journal
    Description: restricted
    Keywords: Biostratigraphy ; Magnetostratigraphy ; Pliocene ; Calabrian Arc ; 04. Solid Earth::04.04. Geology::04.04.08. Sediments: dating, processes, transport ; 04. Solid Earth::04.04. Geology::04.04.10. Stratigraphy ; 04. Solid Earth::04.05. Geomagnetism::04.05.06. Paleomagnetism ; 04. Solid Earth::04.07. Tectonophysics::04.07.02. Geodynamics
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 6
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    Chronology of the Lower-Middle Pleistocene succession of the south-western part of the Crotone Basin (Calabria, Southern Italy) (2011)
    Elsevier
    Details
    Publication Date: 2021-05-17
    Description: Biostratigraphy based on calcareous nannofossils, integrated by magnetostratigraphic, geochronological and isotopic data, allowed establishing a precise chronological framework for the Pleistocene succession within the south-western sector of the Crotone Basin (Calabria, Southern Italy), where the Pliocenee Pleistocene global stratotype section and point is defined, thus demonstrating that sedimentation was quasi-continuous during most of the Lower and Middle Pleistocene. At a large scale, the Pleistocene succession in this sector of the Crotone Basin is characterized by an evident shallowing-upwards trend, showing facies changes from bathyal to shelfal to littoral/continental. However, comparison between adjacent sectors within the investigated area demonstrates that stratigraphic architectures change vastly on very short distances. Our chronological constraints indicate that such changes in sedimentation styles probably occurred in response to differential subsidence rates, which originated tectonically-controlled synsedimentary structures where accommodation space and sediment yield were allotted unevenly. This articulated physiography led to striking differences in the overall thicknesses and organization of Pleistocene stratigraphies and, eventually, to a distinct diachroneity in the first appearance of shallow-marine deposits. In addition, superimposed are complex interplays between regional and local tectonics, eustasy and orbitally-forced climate changes. These interactions have been highlighted by the oxygen isotope stratigraphy established for a part of the studied succession, which is likely to document almost continuously the interval from Marine Isotope Stage (MIS) 26 to MIS 17. In its younger part (post-MIS 17), chronological ties are poor, as the succession is dominated by shallow-water to continental deposits showing a prominent organization into cyclothems. Nevertheless, based on the chronology of the underlying units, it is feasible that basin infill ended during MIS 15-MIS 14 times.
    Description: Published
    Description: 1185-1200
    Description: 2.2. Laboratorio di paleomagnetismo
    Description: JCR Journal
    Description: restricted
    Keywords: Pleistocene ; Chronostratigraphy ; Southern Italy ; 04. Solid Earth::04.04. Geology::04.04.08. Sediments: dating, processes, transport ; 04. Solid Earth::04.05. Geomagnetism::04.05.06. Paleomagnetism
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 7
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    A continuous palaeosecular variation record of the last four millennia from the Augusta Bay (Sicily, Italy) (2011)
    Wiley-Blackwell
    Details
    Publication Date: 2021-06-07
    Description: We present a high-resolution palaeomagnetic and rock magnetic study of two cores, MS06 and MS06-SW (6.7 and 1.1 m long, respectively), collected at 72 m below sea level in the Augusta Bay shelf (Eastern Sicily, Ionian Sea, Italy) about 2.3 kmfrom the coastline. Geophysical surveying carried out in the sampling area highlighted the presence of a homogeneous sedimentary sequence that most likely was deposited after the Last Glacial Maximum and was not affected by anthropogenic disturbances. The two cores penetrated a monotonous mud sedimentary sequence, interrupted at ∼3 m depth by a 3–4-cm-thick volcanic sandy layer that is correlated with the tephra fallout deposit produced by the 122 BC plinian eruption of Mt Etna. This tephra, along with radiocarbon dating of nine marine shells and with radioactive tracers for the uppermost 0.3 m (210Pb and 137Cs), provide the chronological constraints for the stratigraphic sequence that resulted younger than 4500 yr BP. Palaeomagnetic and rock magnetic data show that the sample sequence is magnetically homogeneous. A single peak of high magnetic mineral concentration is present and corresponds to the volcanic sandy layer. Palaeomagnetic data allowed the identification of a well-defined characteristic remanent magnetization that provides a high-resolution record of palaeosecular variation (PSV) at the sampling site. The reconstructed PSV curve is in good agreement with the available regional reference PSV curves and with the prediction from recent PSV modelling for Europe. The palaeomagnetic data obtained in this study on the one hand support and refine the age model for the cores, derived from other independent constraints, and on the other hand provide an original high-resolution PSV curve that can serve as a reference for the central Mediterranean over the last 4 ka.
    Description: Published
    Description: 191 - 202
    Description: 2.2. Laboratorio di paleomagnetismo
    Description: JCR Journal
    Description: restricted
    Keywords: Palaeointensity ; Palaeomagnetic secular variation ; Marine magnetics and palaeomagnetics ; Europe ; 04. Solid Earth::04.05. Geomagnetism::04.05.02. Geomagnetic field variations and reversals ; 04. Solid Earth::04.05. Geomagnetism::04.05.06. Paleomagnetism
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 8
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    Magnetic fabric of Plio-Pleistocene sediments from the Crotone fore-arc basin: Insights on the recent tectonic evolution of the Calabrian Arc (Italy) (2014)
    Elsevier
    Details
    Publication Date: 2020-12-07
    Description: Low-field anisotropy of magnetic susceptibility (AMS) analyses were performed on 532 samples col-lected in 36 (mostly lower Pliocene to lower Pleistocene) marine clay sites from the Crotone basin, afore-arc basin located on top of the external Calabrian accretionary wedge. The Crotone basin formedsince mid-late Miocene under a predominant extensional tectonic regime, but it was influenced there-after by complex interactions with NW–SE left-lateral strike-faults bounding the basin, which also yieldedpost-1.2 Ma ~30◦counterclockwise block rotations. The basin is filled by continental to marine sedimentsyielding one of the thickest and best-exposed Neogene succession available worldwide. The deep-marinefacies – represented by blue-grey marly clays gave the best results, as they both preserved a clear mag-netic fabric, and provided accurate chronology based on previously published magnetostratigraphy andcalcareous plankton (i.e. foraminifers and nannofossils) biostratigraphy. Magnetic susceptibility rangeand rock magnetic analyses both indicate that AMS reflects paramagnetic clay matrix crystal arrange-ment. The fabric is predominantly oblate to triaxial, the anisotropy degree low (〈1.06), and the magneticfoliation mostly subparallel to bedding. Magnetic lineation is defined in 30 out of 36 sites (where thee12 angle is 〈35◦). By also considering local structural analysis data, we find that magnetic fabric wasgenerally acquired during the first tectonic phases occurring after sediment deposition, thus validatingits use as temporally dependent strain proxy. Although most of the magnetic lineations trend NW–SE andare orthogonal to normal faults (as observed elsewhere in Calabria), few NE–SW compressive lineationsshow that the Neogene extensional regime of the Crotone basin was punctuated by compressive episodes.Finally, compressive lineations (prolate magnetic fabric) documented along the strike-slip fault boundingthe basin to the south support the significance of Pleistocene strike-slip tectonics. Thus the Crotone basinshows a markedly different tectonics with respect to other internal and western basins of Calabria, asit yields a magnetic fabric still dominated by extensional tectonics but also revealing arc-normal short-ening episodes and recent strike-slip fault activity. The tectonics documented in the Crotone basin iscompatible with a continuous upper crustal structural reorganization occurring during the SE-migrationof the Calabria terrane above the Ionian subduction system.
    Description: Published
    Description: 67-79
    Description: 1A. Geomagnetismo e Paleomagnetismo
    Description: JCR Journal
    Description: restricted
    Keywords: Calabrian Arc, Anisotropy of magnetic susceptibility, Structural analysis, Fore-arc region ; 04. Solid Earth::04.04. Geology::04.04.08. Sediments: dating, processes, transport ; 04. Solid Earth::04.04. Geology::04.04.09. Structural geology ; 04. Solid Earth::04.05. Geomagnetism::04.05.06. Paleomagnetism ; 04. Solid Earth::04.05. Geomagnetism::04.05.07. Rock magnetism ; 04. Solid Earth::04.07. Tectonophysics::04.07.02. Geodynamics ; 04. Solid Earth::04.07. Tectonophysics::04.07.07. Tectonics
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 9
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    Paleomagnetic evidence for a pre-early Eocene (~50 Ma) bending of the Patagonian orocline (Tierra del Fuego, Argentina): Paleogeographic and tectonic implications (2010)
    Elsevier B.V.
    Details
    Publication Date: 2017-04-04
    Description: The southernmost segment of the Andes of southern Patagonia and Tierra del Fuego forms a ~700 km long orogenic re-entrant with an interlimb angle of ~90° known as Patagonian orocline. No reliable paleomagnetic evidence has been gathered so far to assess whether this great orogenic bend is a primary arc formed over an articulated paleomargin, or is due to bending of a previously less curved (or rectilinear) chain. Here we report on an extensive paleomagnetic and anisotropy of magnetic susceptibility (AMS) study carried out on 22 sites (298 oriented cores), predominantly sampled in Eocene marine clays from the external Magallanes belt of Tierra del Fuego. Five sites (out of six giving reliable paleomagnetic results) containing magnetite and subordinate iron sulphides yield a positive fold test at the 99% significance level, and document no significant rotation since ~50 Ma. Thus, the Patagonian orocline is either a primary bend, or an orocline formed after Cretaceous–earliest Tertiary rotations. Our data imply that the opening of the Drake Passage between South America and Antarctica (probably causing the onset of Antarctica glaciation and global climate cooling), was definitely not related to the formation of the Patagonian orocline, but was likely the sole consequence of the 32±2 Ma Scotia plate spreading. Well-defined magnetic lineations gathered at 18 sites from the Magallanes belt are sub-parallel to (mostly E–W) local fold axes, while they trend randomly at two sites from the Magallanes foreland. Our and previous AMS data consistently show that the Fuegian Andes were characterized by a N–S compression and northward displacing fold–thrust sheets during Eocene–early Miocene times (50–20 Ma), an unexpected kinematics considering coeval South America–Antarctica relative motion. Both paleomagnetic and AMS data suggest no significant influence from the E–W left-lateral Magallanes–Fagnano strike–slip fault system (MFFS), running a few kilometres south of our sampling sites. We thus speculate that strike–slip fault offset in the Fuegian Andes may range in the lower bound values (~20 km) among those proposed so far. In any case our data exclude any influence of strike–slip tectonics on the genesis of the great orogenic bend called Patagonian orocline.
    Description: In press
    Description: 2.2. Laboratorio di paleomagnetismo
    Description: JCR Journal
    Description: reserved
    Keywords: paleomagnetism ; tectonics ; Patagonian orocline ; Fuegian Andes ; Drake Passage ; Magallanes belt ; 04. Solid Earth::04.05. Geomagnetism::04.05.06. Paleomagnetism
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 10
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    A buried volcano in the Calabrian Arc (Italy) revealed by high‐resolution aeromagnetic data (2010)
    American Geophysical Union
    Details
    Publication Date: 2012-02-03
    Description: An edited version of this paper was published by AGU. Copyright (2010) American Geophysical Union.
    Description: Aeromagnetic data collected between the Aeolian volcanoes (southern Tyrrhenian Sea) and the Calabrian Arc (Italy) highlight a WNW‐ESE elongated positive magnetic anomaly centered on the Capo Vaticano morphological ridge (Tyrrhenian coast of Calabria), characterized by an apical, subcircular, flat surface. Results of forward and inverse modeling of the magnetic data show a 20 km long and 3–5 km wide magnetized body that extends from sea floor to about 3 km below sea level. The magnetic properties of this body are consistent with those of the medium to highly evolved volcanic rocks of the Aeolian Arc (i.e., dacites and rhyolites). In the Calabria mainland, widespread dacitic to rhyolitic pumices with calc‐alkaline affinity of Pleistocene age (1–0.7 Ma) are exposed. The tephra falls are related to explosive activity and show a decreasing thickness from the Capo Vaticano area southeastward. The presence of lithics indicates a provenance from a source located not far from Capo Vaticano. The combined interpretation of the magnetic and available geological data reveal that (1) the Capo Vaticano WNW‐ESE elongated positive magnetic anomaly is due to the occurrence of a WNW‐ESE elongated sill; (2) such a sill represents the remnant of the plumbing system of a Pleistocene volcano that erupted explosively producing the pumice tephra exposed in Calabria; and (3) the volcanism is consistent with the Aeolian products, in terms of age, magnetic signature, and geochemical affinity of the erupted products,. The results indicate that such volcanism developed along seismically active faults transversal to the general trend of the Aeolian Arc and Calabria block, in an area where uplift is maximized (∼4 mm/yr). Such uplift could also be responsible for fragmentation of the upper crust and formation of transversal faults along which seismic activity and volcanism occur.
    Description: Published
    Description: B11101
    Description: 3.2. Tettonica attiva
    Description: 3.4. Geomagnetismo
    Description: 5.7. Consulenze in favore di istituzioni nazionali e attività nell'ambito di trattati internazionali
    Description: JCR Journal
    Description: restricted
    Keywords: aeromagnetic anomalies ; volcanic arc ; tectonics of the Calabrian Arc ; risk assessment ; 04. Solid Earth::04.02. Exploration geophysics::04.02.99. General or miscellaneous ; 04. Solid Earth::04.05. Geomagnetism::04.05.04. Magnetic anomalies ; 04. Solid Earth::04.05. Geomagnetism::04.05.07. Rock magnetism ; 04. Solid Earth::04.07. Tectonophysics::04.07.08. Volcanic arcs
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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