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  • 1
    Keywords: Electronic books
    Description / Table of Contents: Intro -- Introduction -- Contents -- Contributors -- Chapter 1: Quality and Standards for Haematopoietic Stem Cells Transplantation Programs -- Quality -- Standards -- Impact -- Conclusion -- References -- Chapter 2: Development of Organizational Quality Management System -- References -- Chapter 3: Document Development, Implementation, Review, Archive, and Disposal -- General -- Start -- Workflow -- Responsibilities -- Duplication of Requirements Between Different Quality Systems -- ICT Systems and Paper Documents -- Education and Document Management -- JACIE on Document Management -- Chapter 4: Audits -- General Concepts -- Definition and Purpose -- Scope -- Types of Audits -- Auditor Requirements -- How to Perform Internal Audit: The Steps of an Internal Audit -- Audit Calendar -- Audit Plan -- Conducting the Audit -- Closing -- Audit Report -- Actions -- Communication of the Result of Internal Audits -- References -- Chapter 5: Qualification and Validation -- Glossary -- Validation Process (Fig. 5.2) -- Example of Documents and Registration Forms for Validation -- Validation Master Plan (VMP) -- Validation Study -- References -- Chapter 6: Outcome Analysis -- What Is Outcome Analysis? -- Standards -- Collecting Data -- Establishing Outcome Analysis for Novel Applications -- Reviewing Data -- References -- Further Reading -- Chapter 7: Personnel Requirements Including Job Descriptions -- Introductıon -- Organisational Structure and Organisational Chart -- Key Personnel -- Personnel Competency -- Responsibility and Task Awareness -- Use of Effective Communication -- Job Descriptions -- Personnel File -- Conclusion -- References -- Chapter 8: Third-Party Agreements -- Gentlemen's Agreement -- Memoranda of Understanding (MoU) [1] -- Contract/Commercial Agreement (Fig. 8.2) -- Service-Level Agreements (SLAs) -- Technical Agreement.
    Type of Medium: Online Resource
    Pages: 1 online resource (189 pages)
    ISBN: 9783030644925
    Language: English
    Note: Description based on publisher supplied metadata and other sources
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  • 2
    Publication Date: 2024-04-25
    Description: 〈title xmlns:mml="http://www.w3.org/1998/Math/MathML"〉Abstract〈/title〉〈p xmlns:mml="http://www.w3.org/1998/Math/MathML" xml:lang="en"〉Dansgaard‐Oeschger (D‐O) climate variability during the last glaciation was first evidenced in ice cores and marine sediments, and is also recorded in various terrestrial paleoclimate archives in Europe. The relative synchronicity across Greenland, the North Atlantic and Europe implies a tight and fast coupling between those regions, most probably effectuated by an atmospheric transmission mechanism. In this study, we investigated the atmospheric changes during Greenland interstadial (GI) and stadial (GS) phases based on regional climate model simulations using two specific periods, GI‐10 and GS‐9 both around 40 ka, as boundary conditions. Our simulations accurately capture the changes in temperature and precipitation as reconstructed by the available proxy data. Moreover, the simulations depict an intensified and southward shifted eddy‐driven jet during the stadial period. Ultimately, this affects the near‐surface circulation toward more southwesterly and cyclonic flow in western Europe during the stadial period, explaining much of the seasonal climate variability recorded by the proxy data, including oxygen isotopes, at the considered proxy sites.〈/p〉
    Description: Plain Language Summary: The climate during the last ice age varied between colder and warmer periods on timescales ranging from hundreds to thousands of years. This variability was first detected in Greenland ice cores and marine sediment cores of the North Atlantic, as well as in continental geological records in Europe. The variation between the colder and warmer periods occur mostly simultaneously in Greenland and in Europe, which is why the atmosphere is assumed to have an important role in transferring the climate signals. We simulated two different periods of the last ice age, one colder and one warmer around 40,000 years ago, using a regional climate model. The aim was to study how the climate and atmospheric circulation changed during these two periods. We find the eddy‐driven jet over the North Atlantic intensified and shifted southward during the colder period. The jet influences the near‐surface atmospheric circulation and leads to more southwesterly and cyclonic flow in western Europe. Oxygen isotope variations observed in western European paleoclimate records may be partly explained by different, more southern moisture sources on top of changes in seasonal temperatures.〈/p〉
    Description: Key Points: 〈list list-type="bullet"〉 〈list-item〉 〈p xml:lang="en"〉Simulated temperatures agree with proxy data; precipitation is biased but GI‐10 versus GS‐9 differences are well captured〈/p〉〈/list-item〉 〈list-item〉 〈p xml:lang="en"〉The stadial winter jet stream is intensified and shifted southward, consistent with dominant southwesterly/cyclonic flow in western Europe〈/p〉〈/list-item〉 〈list-item〉 〈p xml:lang="en"〉Oxygen isotope signal changes at western European proxy sites may be explained not only by temperature but also by varying moisture sources〈/p〉〈/list-item〉 〈/list〉 〈/p〉
    Description: NRDIO
    Description: AXA Research Fund http://dx.doi.org/10.13039/501100001961
    Description: https://doi.org/10.5065/1dfh-6p97
    Keywords: ddc:551.6 ; Dansgaard‐Oeschger cycle ; regional atmospheric dynamics ; regional climate modeling ; continental paleoclimate proxy ; Europe
    Language: English
    Type: doc-type:article
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  • 3
    Publication Date: 2023-08-09
    Description: Planted forests are critical to climate change mitigation and constitute a major supplier of timber/non-timber products and other ecosystem services. Globally, approximately 36% of planted forest area is located in East Asia. However, reliable records of the geographic distribution and tree species composition of these planted forests remain very limited. Here, based on extensive in situ and remote sensing data, as well as an ensemble modeling approach, we present the first spatial database of planted forests for East Asia, which consists of maps of the geographic distribution of planted forests and associated dominant tree genera. Of the predicted planted forest areas in East Asia (948,863 km2), China contributed 87%, most of which is located in the lowland tropical/subtropical regions, and Sichuan Basin. With 95% accuracy and an F1 score of 0.77, our spatially-continuous maps of planted forests enable accurate quantification of the role of planted forests in climate change mitigation. Our findings inform effective decision-making in forest conservation, management, and global restoration projects.
    Language: English
    Type: info:eu-repo/semantics/article
    Format: application/pdf
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  • 4
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    In:  XXVIII General Assembly of the International Union of Geodesy and Geophysics (IUGG)
    Publication Date: 2023-06-01
    Description: This study addresses whether a series of strong substorm-associated MeV electron injections can be a crucial contributor to outer-radiation belt enhancement events. We examine an event that occurred on July 10, 2019, where ~2 MeV electron fluxes increased by ~3 orders of magnitude in only ~7.5-hrs under 4 repetitive, strong relativistic electron injections. For this examination, it is essential to precisely separate purely temporal flux changes from spatial variations observed as Van Allen Probes move along their orbits (i.e., orbital effect). Employing a new “hourly snapshot” analysis approach, we uncover unprecedented details of electron flux dynamics that indicates that the overall outer belt enhancement for this event was not continuous but composed of 4 large discrete flux increases primarily driven by the strong injections. These injections appear as sharp flux increases at all energies when a spacecraft is located in the injection region, and the inner-most L of the flux increase is located farther out with increasing energy as expected for injections. Earthward of the injection region, by comparing hourly snapshots for different times, we infer injections and infer temporally-stable fluxes between injections, despite strong and continuous chorus emission. The fast and intermittent, large flux growths imply cumulative outer belt enhancement via repetitive inward radial transport associated with injection-induced electric fields.
    Language: English
    Type: info:eu-repo/semantics/conferenceObject
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  • 5
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    In:  XXVIII General Assembly of the International Union of Geodesy and Geophysics (IUGG)
    Publication Date: 2023-08-30
    Description: This study covered an area on the western side of the Denman Glacier and the Obruchev Hills, where the predominantly granulite-facies metamorphic rocks exposed of rather different composition. They are intruded by a wide variety of plutonic rocks, including a major batholith of syenitic to granitic composition at David Island. A variety of intrusive rocks (gabbrodiorite, granite-aplite and Bt-granite) of 500 m.a. batholith, exposed at Cape Delay Point, are characterized by high values of magnetic susceptibility (13÷22)×10-3 SI units. However, biotite gabbro has low values. The granosyenites and granodiorites of Hippo Island mainly have high values of magnetic susceptibility (40÷50)×10-3 SI units. The Batholith dyke complex in the area of Cape Kennedy is mainly composed by non-magnetic rocks, with the exception of Bt leucogranite 64×10-3 SI units. Also, the aplite of Gilles Island has high values of magnetic susceptibility (55÷70)×10-3 SI units. The Archean Cape Charcot metamorphic rocks include weakly magnetic paragneisses (4÷5)×10-3 SI units and non-magnetic orthogneisses ~0.3×10-3 SI units. Metamorphic rocks of the Davis Peninsula basement are characterized by values of (0.05÷9)×10-3 SI units and are represented by Amf-Bt orthogneisses and banded gneisses. Thus, the main sources of anomalies in the studied area are intrusive rocks of batholith, while Archean crystalline basement only forms a common magnetic background. The magnetic rocks of the Obruchev Hills and Cape Jones are represented by (±Px)-Amf-Bt orthogneisses (30÷90)×10-3 SI units, which form the main anomaly magnetic field pattern. Magnetic susceptibility values for Sill-Bt and Grt-Bt paragneisses do not exceed 0.4×10-3 SI units.
    Language: English
    Type: info:eu-repo/semantics/conferenceObject
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  • 6
    Publication Date: 2023-07-01
    Description: Small-scale magnetic flux ropes (SMFRs), a bundle of twisted field lines, have been discovered in the solar wind at 1AU. It is widely known that rotating magnetic field structure is favorable for build-up, release, and transport of free energy. However, their interaction with the Earth’s magnetosphere has not yet been extensively studied even though it may play an important role in energy transfer from the solar wind to the geospace environment. We report on the effect of SMFRs on the Solar Wind – Magnetosphere – Ionosphere coupling process. SMFR events used in this study are identified by Grad-Shafranov (GS) reconstruction algorithm which has been used in a number of SMFR studies. Our pilot study found 454 SMFRs from Magnetospheric Multiscale (MMS) mission near the Earth’s magnetospheric boundary from 11/15/2017 to 03/13/2018. During this period, we perform a statistical analysis of SMFRs from both MMS and Wind spacecraft to compare their occurrence and characteristics, and to determine SMFR-related solar wind conditions. We also use several magnetospheric missions (e.g., RBSP, THEMIS, GOES, etc) and ground-based instruments (e.g., magnetometers, all sky imagers, etc) to understand a global picture of geospace responses to SMFRs. Here we present simultaneous in-situ and ground observations in association with SMFR events.
    Language: English
    Type: info:eu-repo/semantics/conferenceObject
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  • 7
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    In:  XXVIII General Assembly of the International Union of Geodesy and Geophysics (IUGG)
    Publication Date: 2023-08-09
    Description: Air quality monitoring is vital because air pollution caused by particulate matter invokes social problems and adversely affects human health. The atmospheric boundary-layer and its sub-layers strongly influence the spatiotemporal distributions of air pollutants and hence modulating air quality. Thus, continuous measurements of the atmospheric boundary-layer are needed to assess air quality and air pollution. A ceilometer vertically emits a laser pulse of a single wavelength into the atmosphere and measures the returned intensity of backscattered laser by atmospheric hydrometeors (e.g., aerosols and cloud particles), which allows determining the atmospheric boundary-layer height (ABLH) based on the ceilometer measurements. Thus, dense ceilometer measurement networks have emerged across the world for sampling the ABLH vertical profile. In this study, two different ceilometer measurement networks (i.e., the National Institute of Environmental Research (NIER) and the Korea Meteorological Administration (KMA)) in the Republic of Korea were introduced. The models and specifications of the installed ceilometers in these networks were explained. A new generalized algorithm calculating ABLH based on a gradient method, applicable to all installed ceilometers of the NIER and KMA networks, was developed. The impacts of the selection of spatial (i.e., vertical) and temporal resolutions of vertical profiling on the calculations of ABLH were quantified for different ceilometers. The optimal spatial and temporal resolutions for determining ABLH based on ceilometer measurements were also determined.
    Language: English
    Type: info:eu-repo/semantics/conferenceObject
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  • 8
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    In:  XXVIII General Assembly of the International Union of Geodesy and Geophysics (IUGG)
    Publication Date: 2023-06-08
    Description: A significant advancement in our understanding of the effects of extratropical climate on remote regions has been achieved through the flurry of evidence in paleoclimate proxies and model experiments. Although the theoretical framework provides valuable insight into understanding the tropical response to extratropical thermal forcing, it is mostly based on steady-state responses. This study examines the spatial and temporal evolution of pole-to-pole teleconnection by utilizing the benefits of an idealized general circulation model. The well-designed experiment reveals that tropical precipitation depends profoundly on the time scale of extratropical sources: unaltered by sufficiently high-frequency extratropical forcing. The extratropics-to-tropics teleconnection preferentially occurs through the lower tropospheric layer. Transient eddies to diffuse moist static energy perturb the midlatitude SSTs outside the forcing region. The transient eddies weaken in the subtropics and are transported further equatorward through the Hadley circulation. The crucial role of each dynamic process is well supported by theoretical models. Understanding these dynamics helps broaden the scope of extratropical thermal forcing to a pole-to-pole thermal connection. The mechanism and its implications provide a benchmark for the impact of extratropical climate change in realistic climate models.
    Language: English
    Type: info:eu-repo/semantics/conferenceObject
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  • 9
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    In:  XXVIII General Assembly of the International Union of Geodesy and Geophysics (IUGG)
    Publication Date: 2023-06-28
    Description: To facilitate geological studies of the Antarctic region south of 60〈sup〉o〈/sup〉S, Kim et al. (2022) used equivalent point magnetic dipole inversion to produce the comprehensive airborne-to-satellite altitude ADMAP-2s magnetic anomaly model. The ADMAP-2s spherical coordinate anomaly predictions jointly match crustal magnetic anomaly observations from the Swarm satellite mission (Haagmans et al., 2010) and the Antarctic Digital Magnetic Anomaly Project’s (ADMAP) second-generation magnetic anomaly grid (ADMAP-2), which was compiled from over 3.5 million line-km of aeromagnetic and shipborne survey data (Golynsky et al., 2017). The present study investigates the utility of point dipole modeling for differentially reducing the magnetic anomalies to the pole, as well as estimating their first and second order vertical gradient and pseudo gravity anomalies. These anomaly attributes facilitate characterizing the remanent components and correlating the anomalies with possible subsurface sources and affiliated gravity anomalies. The efficacy of the gravity point mass or pole is investigated for processing regional patches of gravity anomalies for subsurface information and correlating them with affiliated magnetic anomalies. Crustal geology associations are also considered for the regional magnetic anomaly features of West and East Antarctica and the southern Atlantic, Indian, and Pacific oceans.
    Language: English
    Type: info:eu-repo/semantics/conferenceObject
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  • 10
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    In:  XXVIII General Assembly of the International Union of Geodesy and Geophysics (IUGG)
    Publication Date: 2023-06-27
    Description: Concurrent daytime and nighttime heat extremes (CHW) occur when both the daytime and nighttime temperatures during a heatwave are significantly higher than normal for an extended period of time. It means that not only are daytime temperatures reaching extreme levels, but nighttime temperatures are also remaining at high levels, providing little relief from the heat. CHW can be particularly dangerous as it can lead to extended periods of high heat stress, which can cause heat exhaustion, dehydration, and heat stroke, as well as other health problems. Those concurrent heat extremes recently increased over East Asia, especially in Korea. However, there are few previous studies examining CHW in Korea, and atmospheric circulation associated with CHW have not been investigated in previous studies. In this study, therefore, we tried to understand the characteristics of recently increased CHW by simply classifying it with the Self-Organizing Map clustering method. This study revealed large-scale atmospheric circulations associated with CHWs and patterns of increased clusters during recent periods. In addition, the effect of recently increased land-atmosphere interactions on CHW is examined. Due to global warming trends, we expect that CHW is favorable for more extreme increases in the future, occurring more robust and long-lived CHWs more likely.
    Language: English
    Type: info:eu-repo/semantics/conferenceObject
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