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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 82 (1978), S. 22-26 
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Depuis 1967 nous utilisons, pour le traitement des mélanomes des membres, un système de perfusion au melphalan en hyperthermie. Le présent rapport complète une première étude de follow-up présentée en 1975 et portant sur 165 malades qui ont eu 185 perfusions. Les 70 malades classés stade I (classification de Clark-From) ont une survie à 5 ans de 86.3%. Pour les 73 malades aux stades II et III, la survie à 5 ans est de 52.5%. L'amélioration de la survie est spécialement importante pour les malades au stade IIIA: 22.2% avant la perfusion hyperthermique, 74% des 30 cas qui ont bénéficié de cette technique.
    Notes: Abstract Since 1967, we have used a system of hyperthermic perfusion with melphalan to treat patients with melanoma of the extremities. This report presents additional follow-up data on 165 patients, first reported on in 1975, who underwent 185 perfusions. The 70 patients classified as stage I (Stehlin classification system) had a 5-year survival rate of 86.3%. The 5-year survival rate for the 73 patients with stage II and stage III disease was 52.5%. There was a dramatic increase in the 5-year survival rate for patients with stage IIIA disease, from 22.2% prior to the use of heat to 74% for 30 patients undergoing hyperthermic perfusion.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Archive for rational mechanics and analysis 63 (1977), S. 205-252 
    ISSN: 1432-0673
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Type of Medium: Electronic Resource
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  • 4
    Publication Date: 2022-05-26
    Description: Dataset: GN01 Particulate Thorium and Protactinium
    Description: This dataset contains concentrations of size-fractionated particulate thorium and protactinium isotopes (Th-232, Th-230, Pa-231) in seawater collected during the U.S. GEOTRACES Arctic cruise (HLY1502, GN01) on USCGC Healy from August to October 2015. This is compiled data produced by two laboratories with the following associations: Lamont-Doherty Earth Observatory of Columbia University (LDEO) and the University of Minnesota (UMN). All data have been deemed intercalibrated by the International GEOTRACES Standards and Intercalibration (S&I) Committee. For a complete list of measurements, refer to the full dataset description in the supplemental file 'Dataset_description.pdf'. The most current version of this dataset is available at: https://www.bco-dmo.org/dataset/834741
    Description: NSF Division of Ocean Sciences (NSF OCE) OCE-1434479, NSF Division of Ocean Sciences (NSF OCE) OCE-1434886
    Description: 2021-07-31
    Repository Name: Woods Hole Open Access Server
    Type: Dataset
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  • 5
    Publication Date: 2022-10-26
    Description: Author Posting. © American Geophysical Union, 2022. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Global Biogeochemical Cycles 36(6), (2022): e2022GB007330, https://doi.org/10.1029/2022gb007330.
    Description: Processes controlling dissolved barium (dBa) were investigated along the GEOTRACES GA03 North Atlantic and GP16 Eastern Tropical Pacific transects, which traversed similar physical and biogeochemical provinces. Dissolved Ba concentrations are lowest in surface waters (∼35–50 nmol kg−1) and increase to 70–80 and 140–150 nmol kg−1 in deep waters of the Atlantic and Pacific transects, respectively. Using water mass mixing models, we estimate conservative mixing that accounts for most of dBa variability in both transects. To examine nonconservative processes, particulate excess Ba (pBaxs) formation and dissolution rates were tracked by normalizing particulate excess 230Th activities. Th-normalized pBaxs fluxes, with barite as the likely phase, have subsurface maxima in the top 1,000 m (∼100–200 μmol m−2 year−1 average) in both basins. Barite precipitation depletes dBa within oxygen minimum zones from concentrations predicted by water mass mixing, whereas inputs from continental margins, particle dissolution in the water column, and benthic diffusive flux raise dBa above predications. Average pBaxs burial efficiencies along GA03 and GP16 are ∼37% and 17%–100%, respectively, and do not seem to be predicated on barite saturation indices in the overlying water column. Using published values, we reevaluate the global freshwater dBa river input as 6.6 ± 3.9 Gmol year−1. Estuarine mixing processes may add another 3–13 Gmol year−1. Dissolved Ba inputs from broad shallow continental margins, previously unaccounted for in global marine summaries, are substantial (∼17 Gmol year−1), exceeding terrestrial freshwater inputs. Revising river and shelf dBa inputs may help bring the marine Ba isotope budget more into balance.
    Description: The International GEOTRACES Programme is possible in part thanks to the support from the U.S. National Science Foundation (Grant OCE-1840868) to the Scientific Committee on Oceanic Research (SCOR). This research was supported by the National Science Foundation under Grant No. NSF OCE-0927951, NSF OCE-1137851, NSF OCE-1261214, and NSF OCE-1925503 to A. M. Shiller; NSF OCE-1829563 to R. F. Anderson; NSF OCE-0927064 and NSF OCE-1233688 to R. F. Anderson and M. Q. Fleisher; NSF OCE-0927754 to R. Lawrence Edwards; NSF OCE-1233903 to R. Lawrence Edwards and H. Cheng; NSF OCE-0926860 to L. F. Robinson; NSF OCE-0963026 and NSF OCE-1518110 to P. J. Lam; and NSF OCE-1232814 to B. S. Twining.
    Keywords: Barium ; Excess barium ; Barite ; GEOTRACES ; Th-normalized flux ; Burial efficiency
    Repository Name: Woods Hole Open Access Server
    Type: Article
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  • 6
    Publication Date: 2022-10-19
    Description: Author Posting. © American Geophysical Union, 2021. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Paleoceanography and Paleoclimatology 36(9), (2021): e2021PA004226, https://doi.org/10.1029/2021PA004226.
    Description: The deep ocean has long been recognized as the reservoir that stores the carbon dioxide (CO2) removed from the atmosphere during Pleistocene glacial periods. The removal of glacial atmospheric CO2 into the ocean is likely modulated by an increase in the degree of utilization of macronutrients at the sea surface and enhanced storage of respired CO2 in the deep ocean, known as enhanced efficiency of the biological pump. Enhanced biological pump efficiency during glacial periods is most easily documented in the deep ocean using proxies for oxygen concentrations, which are directly linked to respiratory CO2 levels. We document the enhanced storage of respired CO2 during the Last Glacial Maximum (LGM) in the Pacific Southern Ocean and deepest Equatorial Pacific using records of deglacial authigenic manganese, which form as relict peaks during increases in bottom water oxygen (BWO) concentration. These peaks are found at depths and regions where other oxygenation histories have been ambiguous, due to diagenetic alteration of authigenic uranium, another proxy for BWO. Our results require that the entirety of the abyssal Pacific below approximately 1,000 m was enriched in respired CO2 and depleted in oxygen during the LGM. The presence of authigenic Mn enrichment in the deep Equatorial Pacific for each of the last five deglaciations suggests that the storage of respired CO2 in the deep ocean is a ubiquitous feature of late-Pleistocene ice ages.
    Description: This work was performed with support from the National Science Foundation (NSF) over about 30 years. The TT013 and NBP9802 cores were collected during the U.S. JGOFS program. Their collection and analyses were supported by NSF OCE-9022301 and OPP-95303398 to R. F. Anderson, and NSF OCE 9301097 to R. W. Murray. Coring and radiocarbon analyses on NBP1702 were funded by NSF OPP-1542962. XRF analysis on NBP9802 and NBP1702 cores, as well as additional radiocarbon measurements, was funded by an LDEO Climate Center Grant to F. J. Pavia.
    Description: 2022-02-17
    Keywords: Manganese ; Southern Ocean ; Pacific Ocean ; Respired carbon ; Bottom water oxygen ; Deglaciations
    Repository Name: Woods Hole Open Access Server
    Type: Article
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  • 7
    Publication Date: 2022-10-26
    Description: © The Author(s), 2021. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Hayes, C. T., Costa, K. M., Anderson, R. F., Calvo, E., Chase, Z., Demina, L. L., Dutay, J., German, C. R., Heimburger-Boavida, L., Jaccard, S. L., Jacobel, A., Kohfeld, K. E., Kravchishina, M. D., Lippold, J., Mekik, F., Missiaen, L., Pavia, F. J., Paytan, A., Pedrosa-Pamies, R., Petrova, M., V., Rahman, S., Robinson, L. F., Roy-Barman, M., Sanchez-Vidal, A., Shiller, A., Tagliabue, A., Tessin, A. C., van Hulten, M., & Zhang, J. Global ocean sediment composition and burial flux in the deep sea. Global Biogeochemical Cycles, 35(4), (2021): e2020GB006769, https://doi.org/10.1029/2020GB006769.
    Description: Quantitative knowledge about the burial of sedimentary components at the seafloor has wide-ranging implications in ocean science, from global climate to continental weathering. The use of 230Th-normalized fluxes reduces uncertainties that many prior studies faced by accounting for the effects of sediment redistribution by bottom currents and minimizing the impact of age model uncertainty. Here we employ a recently compiled global data set of 230Th-normalized fluxes with an updated database of seafloor surface sediment composition to derive atlases of the deep-sea burial flux of calcium carbonate, biogenic opal, total organic carbon (TOC), nonbiogenic material, iron, mercury, and excess barium (Baxs). The spatial patterns of major component burial are mainly consistent with prior work, but the new quantitative estimates allow evaluations of deep-sea budgets. Our integrated deep-sea burial fluxes are 136 Tg C/yr CaCO3, 153 Tg Si/yr opal, 20Tg C/yr TOC, 220 Mg Hg/yr, and 2.6 Tg Baxs/yr. This opal flux is roughly a factor of 2 increase over previous estimates, with important implications for the global Si cycle. Sedimentary Fe fluxes reflect a mixture of sources including lithogenic material, hydrothermal inputs and authigenic phases. The fluxes of some commonly used paleo-productivity proxies (TOC, biogenic opal, and Baxs) are not well-correlated geographically with satellite-based productivity estimates. Our new compilation of sedimentary fluxes provides detailed regional and global information, which will help refine the understanding of sediment preservation.
    Description: This study was supported by the Past Global Changes (PAGES) project, which in turn received support from the Swiss Academy of Sciences and the US-NSF. The work grew out of a 2018 workshop in Aix-Marseille, France, funded by PAGES, GEOTRACES, SCOR, US-NSF, Aix Marseille Université, and John Cantle Scientific, and the authors would like to acknowledge all attendees of this meeting. The authors acknowledge the participants of the 68th cruise of RV Akademik Mstislav Keldysh for helping acquire samples. Christopher T. Hayes acknowledges support from US-NSF awards 1658445 and 1737023. Some data compilation on Arctic shelf seas was supported by the Russian Science Foundation, grant number 20-17-00157. This work was also supported through project CRESCENDO (grant no. 641816, European Commission). Zanna Chase acknowledges support from the Australian Research Council’s Discovery Projects funding scheme (project DP180102357). Christopher R. German acknowledges US-NSF awards 1235248 and 1234827. Some colorbars used in the figures were designed by Kristen Thyng et al. (2016) and Patrick Rafter.
    Keywords: Barium ; Carbon cycle ; Marine atlas ; Mercury ; Opal ; Sediment burial
    Repository Name: Woods Hole Open Access Server
    Type: Article
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  • 8
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    Biological and Chemical Oceanography Data Management Office (BCO-DMO). Contact: bco-dmo-data@whoi.edu
    Publication Date: 2022-05-27
    Description: Dataset: NBP1702 Dissolved Th and Pa
    Description: This dataset contains depth profiles of seawater dissolved 232Th, 230Th, and 231Pa from cruise NBP1702 (GEOTRACES-compliant). For a complete list of measurements, refer to the full dataset description in the supplemental file 'Dataset_description.pdf'. The most current version of this dataset is available at: https://www.bco-dmo.org/dataset/813379
    Description: NSF Office of Polar Programs (formerly NSF PLR) (NSF OPP) OPP-1542962
    Repository Name: Woods Hole Open Access Server
    Type: Dataset
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  • 9
    Publication Date: 2022-05-27
    Description: Dataset: GN01 Dissolved Thorium and Protactinium
    Description: This dataset contains concentrations of dissolved thorium and protactinium isotopes (Th-232, Th-230, Pa-231) in seawater, sea ice, and melt ponds collected during the U.S. GEOTRACES Arctic cruise (HLY1502, GN01) on USCGC Healy from August to October 2015. This is compiled data produced by two laboratories with the following associations: Lamont-Doherty Earth Observatory of Columbia University (LDEO) and the University of Minnesota (UMN). All data have been deemed intercalibrated by the International GEOTRACES Standards and Intercalibration (S&I) Committee. For a complete list of measurements, refer to the full dataset description in the supplemental file 'Dataset_description.pdf'. The most current version of this dataset is available at: https://www.bco-dmo.org/dataset/833887
    Description: NSF Division of Ocean Sciences (NSF OCE) OCE-1434479, NSF Division of Ocean Sciences (NSF OCE) OCE-1434886
    Repository Name: Woods Hole Open Access Server
    Type: Dataset
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  • 10
    Publication Date: 2022-05-27
    Description: Dataset: GN01 Particulate Thorium and Protactinium
    Description: This dataset contains concentrations of size-fractionated particulate thorium and protactinium isotopes (Th-232, Th-230, Pa-231) in seawater collected during the U.S. GEOTRACES Arctic cruise (HLY1502, GN01) on USCGC Healy from August to October 2015. This is compiled data produced by two laboratories with the following associations: Lamont-Doherty Earth Observatory of Columbia University (LDEO) and the University of Minnesota (UMN). All data have been deemed intercalibrated by the International GEOTRACES Standards and Intercalibration (S&I) Committee. For a complete list of measurements, refer to the full dataset description in the supplemental file 'Dataset_description.pdf'. The most current version of this dataset is available at: https://www.bco-dmo.org/dataset/834741
    Description: NSF Division of Ocean Sciences (NSF OCE) OCE-1434479, NSF Division of Ocean Sciences (NSF OCE) OCE-1434886
    Repository Name: Woods Hole Open Access Server
    Type: Dataset
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