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  • 1
    Online Resource
    Online Resource
    Contrast-enhanced CT based radiomics in the preoperative prediction of perineural invasion for patients with gastric cancer
    Elsevier BV ; 2022
    In:  European Journal of Radiology Vol. 154 ( 2022-09), p. 110393-
    Details
    In: European Journal of Radiology, Elsevier BV, Vol. 154 ( 2022-09), p. 110393-
    Type of Medium: Online Resource
    ISSN: 0720-048X
    URL: Article
    DOI: 10.1016/j.ejrad.2022.110393
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2022
    detail.hit.zdb_id: 2005350-2
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  • 2
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    Comparative study of automatic and manual planning methods for volumetric modulated arc therapy in patients with intraocular cancer
    Wiley ; 2020
    In:  Precision Radiation Oncology Vol. 4, No. 3 ( 2020-09), p. 68-72
    Details
    In: Precision Radiation Oncology, Wiley, Vol. 4, No. 3 ( 2020-09), p. 68-72
    Abstract: To research and assess automatic volumetric modulated arc therapy (VMAT) planning methods for patients with intraocular cancer. Methods The mdaccAutoPlan system was added to the Pinnacle 3 treatment planning system as a plug‐in. Automatic VMAT plans were generated for 10 patients diagnosed with intraocular cancer, and evaluated according to standard dose‐volume histogram parameters. Results The planning target volume of enrolled patients ranges from 14.24 to 50.69 cm 3 . Both planning methods lead to acceptable planning target volume target coverage with a V95 of 97.9 ± 1.4% and 96.4 ± 1.5% for manual and automatic plans ( P  = 0.03), respectively. Automatic planning lowered the dose delivered to the ipsilateral lens and optical nerves, but increased the dose to the brainstem compared with manual planning. Automatic planning significantly prolonged VMAT planning time (3.25 ± 0.53 h vs. 1.02 ± 0.69 h, P   〈  0.01), but no significant differences were seen in average machine units (474.0 ± 64.8 vs. 502.4 ± 109.5, P  = 0.34) compared with the manual planning method. Conclusions Automatic VMAT planning achieved acceptable target coverage, and lowered the dose delivered to ipsilateral lens and brainstem in patients with intraocular cancer compared with manual planning. However, the full benefits of automatic VMAT planning require further study with improved performance and treatment planning system capacity.
    Type of Medium: Online Resource
    ISSN: 2398-7324 , 2398-7324
    URL: Issue
    URL: Article
    DOI: 10.1002/pro6.v4.3
    DOI: 10.1002/pro6.1099
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2899107-2
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  • 3
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    Precise delineation and tumor localization based on novel image registration strategy between optical coherence tomography and computed tomography in the radiotherapy of intraocular cancer
    IOP Publishing ; 2019
    In:  Physics in Medicine & Biology Vol. 64, No. 12 ( 2019-06-12), p. 125009-
    Details
    In: Physics in Medicine & Biology, IOP Publishing, Vol. 64, No. 12 ( 2019-06-12), p. 125009-
    Type of Medium: Online Resource
    ISSN: 1361-6560
    URL: Article
    DOI: 10.1088/1361-6560/ab0ddf
    Language: Unknown
    Publisher: IOP Publishing
    Publication Date: 2019
    detail.hit.zdb_id: 1473501-5
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  • 4
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    Cross verification of independent dose recalculation, log files based, and phantom measurement‐based pretreatment quality assurance for volumetric modulated arc therapy
    Wiley ; 2020
    In:  Journal of Applied Clinical Medical Physics Vol. 21, No. 11 ( 2020-11), p. 98-104
    Details
    In: Journal of Applied Clinical Medical Physics, Wiley, Vol. 21, No. 11 ( 2020-11), p. 98-104
    Abstract: Independent treatment planning system (TPS) check with Mobius3D software, log files based quality assurance (QA) with MobiusFX, and phantom measurement‐based QA with ArcCHECK were performed and cross verified for head‐and‐neck (17 patients), chest (16 patients), and abdominal (19 patients) cancer patients who underwent volumetric modulated arc therapy (VMAT). Dosimetric differences and percentage gamma passing rates (%GPs) were evaluated and compared for this cross verification. For the dosimetric differences in planning target volume (PTV) coverage, there was no significant difference among TPS vs. Mobius3D, TPS vs. MobiusFX, and TPS vs. ArcCHECK. For the dosimetric differences in organs at risks (OARs), the number of metrics with an average dosimetric differences higher than ±3% for TPS vs Mobius3D, TPS vs MobiusFX, and TPS vs ArcCHECK were 1, 1, 7; 2, 1, 4; 1, 1, 5 for the patients with head‐and‐neck, abdomen, and chest cancer, respectively. The %GPs of global gamma indices for Mobius3D and MobiousFX were above 97%, while it ranged from 92% to 96% for ArcCHECK. The %GPs of individual volume‐based gamma indices were around 98% for Mobius3D and MobiousFX, except for γPTV for chest and abdominal cancer (88.9% to 92%); while it ranged from 86% to 99% for ArcCHECK. In conclusion, some differences in dosimetric metrics and gamma passing rates were observed with ArcCHECK measurement‐based QA in comparison with independent dosecheck and log files based QA. Care must be taken when considering replacing phantom measurement‐based IMRT/VMAT QA.
    Type of Medium: Online Resource
    ISSN: 1526-9914 , 1526-9914
    URL: Issue
    URL: Article
    DOI: 10.1002/acm2.v21.11
    DOI: 10.1002/acm2.13036
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2010347-5
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  • 5
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    Impact of setup errors on multi‐isocenter volumetric modulated arc therapy for craniospinal irradiation
    Wiley ; 2020
    In:  Journal of Applied Clinical Medical Physics Vol. 21, No. 11 ( 2020-11), p. 115-123
    Details
    In: Journal of Applied Clinical Medical Physics, Wiley, Vol. 21, No. 11 ( 2020-11), p. 115-123
    Abstract: Multi‐isocenter volumetric modulated arc therapy (VMAT) is recommended for craniospinal irradiation (CSI) to smooth the dose distribution in the junction regions relying solely on inverse optimization. However, few studies have measured the dosimetric impact of setup errors on this multi‐isocenter VMAT in the junction areas. The purpose of this study is to evaluate the impact of positional errors during VMAT CSI with two‐dimension (2D) and three‐dimension (3D) dosimetric measurements. A total of 20 patients treated by three‐isocenter VMAT CSI were retrospectively reviewed and analyzed. A 3D diode array ArcCHECK and radiochromic film EBT3 were applied to measure the percentage gamma passing rates (%GPs) and dose distributions in the junction areas between the cranial/upper‐spinal and the upper/lower‐spinal fields with intentionally introduced setup errors of ± 1 mm, ±2 mm, ±3 mm, ±5 mm, and ± 8 mm, respectively. The length and volume of planning target volume (PTV) for these CSI patients ranged from 50.14 to 80.8 cm, and 1572.3 to 2114.5 cm 3 , respectively. The %GPs for ±3 mm, ±5 mm, and ±8 mm positional errors were around 95%, 90%, and 85%, respectively, in the junction areas. The dosimetric verification results with EBT3 films indicated that cold and hot areas were observed with the increase of introduced setup errors. In conclusion, the dosimetric verification with intentionally introduced setup errors demonstrated that positional errors within 3 mm have a little impact for VMAT CSI, although setup errors should be minimized. Relying on the inverse optimization of VMAT to smooth the dose distribution in the junction areas is feasible for CSI.
    Type of Medium: Online Resource
    ISSN: 1526-9914 , 1526-9914
    URL: Issue
    URL: Article
    DOI: 10.1002/acm2.v21.11
    DOI: 10.1002/acm2.13044
    Language: English
    Publisher: Wiley
    Publication Date: 2020
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  • 6
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    Individual volume‐based 3D gamma indices for pretreatment VMAT QA
    Wiley ; 2017
    In:  Journal of Applied Clinical Medical Physics Vol. 18, No. 3 ( 2017-05), p. 28-36
    Details
    In: Journal of Applied Clinical Medical Physics, Wiley, Vol. 18, No. 3 ( 2017-05), p. 28-36
    Abstract: Although gamma analysis is still a widely accepted quantitative tool to analyze and report patient‐specific QA for intensity‐modulated radiotherapy ( IMRT ) and volumetric‐modulated arc therapy ( VMAT ), the correlation between the 2D percentage gamma passing rate (% GP ), and the clinical dosimetric difference for IMRT and VMAT has been questioned. The purpose of this study was to investigate the feasibility of individual volume‐based 3D gamma indices for pretreatment VMAT QA . Percentage dosimetric errors (% DE ) of dose‐volume histogram metrics (includes target volumes and organ at risks) between the treatment planning system and QA ‐reconstructed dose distribution, % GPs for individual volume and global gamma indices, as well their correlations and sensitivities were investigated for one‐ and two‐arc VMAT plans. The % GP s of individual volumes had a higher percent of correlation with individual 15 % DE metrics compared with global % GP s. For two‐arc VMAT at 2%/2 mm, 3%/3 mm, and 4%/4 mm criteria, individual volume % GP s were correlated with 9, 12, and 9 out of 15 % DE metrics, while global % GP s were correlated with only 2 out of 15 % DE metrics, respectively. For one‐arc VMAT at 2%/2 mm, 3%/3 mm, and 4%/4 mm criteria, individual volume % GP s were correlated with 18, 16, and 13 out of 23 % DE metrics, and global % GP s were correlated with 19, 12, and 1 out 23 % DE metrics, respectively. The area under curves ( AUC ) of individual volume % GP s were higher than those of global % GP s for two‐arc VMAT plans, but with mixed results for one‐arc VMAT plans. In a conclusion, the idea of individual volume % GP was created and investigated to better serve for VMAT QA and individual volume‐based % GP had a higher percent of correlation with DVH 15 % DE metrics compared with global % GP for both one‐ and two‐arc VMAT plans.
    Type of Medium: Online Resource
    ISSN: 1526-9914 , 1526-9914
    URL: Issue
    URL: Article
    DOI: 10.1002/acm2.2017.18.issue-3
    DOI: 10.1002/acm2.12062
    Language: English
    Publisher: Wiley
    Publication Date: 2017
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  • 7
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    Integrating plan complexity and dosiomics features with deep learning in patient-specific quality assurance for volumetric modulated arc therapy
    Springer Science and Business Media LLC ; 2023
    In:  Radiation Oncology Vol. 18, No. 1 ( 2023-07-11)
    Details
    In: Radiation Oncology, Springer Science and Business Media LLC, Vol. 18, No. 1 ( 2023-07-11)
    Abstract: To investigate the feasibility and performance of deep learning (DL) models combined with plan complexity (PC) and dosiomics features in the patient-specific quality assurance (PSQA) for patients underwent volumetric modulated arc therapy (VMAT). Methods Total of 201 VMAT plans with measured PSQA results were retrospectively enrolled and divided into training and testing sets randomly at 7:3. PC metrics were calculated using house-built algorithm based on Matlab. Dosiomics features were extracted and selected using Random Forest (RF) from planning target volume (PTV) and overlap regions with 3D dose distributions. The top 50 dosiomics and 5 PC features were selected based on feature importance screening. A DL DenseNet was adapted and trained for the PSQA prediction. Results The measured average gamma passing rate (GPR) of these VMAT plans was 97.94% ± 1.87%, 94.33% ± 3.22%, and 87.27% ± 4.81% at the criteria of 3%/3 mm, 3%/2 mm, and 2%/2 mm, respectively. Models with PC features alone demonstrated the lowest area under curve (AUC). The AUC and sensitivity of PC and dosiomics (D) combined model at 2%/2 mm were 0.915 and 0.833, respectively. The AUCs of DL models were improved from 0.943, 0.849, 0.841 to 0.948, 0.890, 0.942 in the combined models (PC + D + DL) at 3%/3 mm, 3%/2 mm and 2%/2 mm, respectively. A best AUC of 0.942 with a sensitivity, specificity and accuracy of 100%, 81.8%, and 83.6% was achieved with combined model (PC + D + DL) at 2%/2 mm. Conclusions Integrating DL with dosiomics and PC metrics is promising in the prediction of GPRs in PSQA for patients underwent VMAT.
    Type of Medium: Online Resource
    ISSN: 1748-717X
    URL: Article
    DOI: 10.1186/s13014-023-02311-7
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 2224965-5
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  • 8
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    Dosimetric advantage of volumetric modulated arc therapy in the treatment of intraocular cancer
    Springer Science and Business Media LLC ; 2017
    In:  Radiation Oncology Vol. 12, No. 1 ( 2017-12)
    Details
    In: Radiation Oncology, Springer Science and Business Media LLC, Vol. 12, No. 1 ( 2017-12)
    Type of Medium: Online Resource
    ISSN: 1748-717X
    URL: Article
    DOI: 10.1186/s13014-017-0819-7
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2017
    detail.hit.zdb_id: 2224965-5
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  • 9
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    Prediction of response after chemoradiation for esophageal cancer using a combination of dosimetry and CT radiomics
    Springer Science and Business Media LLC ; 2019
    In:  European Radiology Vol. 29, No. 11 ( 2019-11), p. 6080-6088
    Details
    In: European Radiology, Springer Science and Business Media LLC, Vol. 29, No. 11 ( 2019-11), p. 6080-6088
    Type of Medium: Online Resource
    ISSN: 0938-7994 , 1432-1084
    URL: Article
    DOI: 10.1007/s00330-019-06193-w
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2019
    detail.hit.zdb_id: 1472718-3
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  • 10
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    Dosimetric benefits of intensity‐modulated radiotherapy and volumetric‐modulated arc therapy in the treatment of postoperative cervical cancer patients
    Wiley ; 2017
    In:  Journal of Applied Clinical Medical Physics Vol. 18, No. 1 ( 2017-01), p. 25-31
    Details
    In: Journal of Applied Clinical Medical Physics, Wiley, Vol. 18, No. 1 ( 2017-01), p. 25-31
    Abstract: As the advantage of using complex volumetric‐modulated arc therapy ( VMAT ) in the treatment of gynecologic cancer has not yet been fully determined, the purpose of this study was to investigate the dosimetric advantages of VMAT by comparing directly with whole pelvic conformal radiotherapy ( CRT ) and intensity‐modulated radiotherapy ( IMRT ) in the treatment of 15 postoperative cervical cancer patients. Four‐field CRT , seven‐field IMRT , and two‐arc VMAT plans were generated for each patient with identical objective functions to achieve clinically acceptable dose distribution. Target coverage and OAR sparing differences were investigated through dose‐volume histogram ( DVH ) analysis. Nondosimtric differences between IMRT and VMAT were also compared. Target coverage presented by V95% were 88.9% ± 3.8%, 99.9% ± 0.07%, and 99.9% ± 0.1% for CRT , IMRT , and VMAT , respectively. Significant differences on conformal index ( CI ) and conformal number ( CN ) were observed with CI s of 0.37 ± 0.07, 0.55 ± 0.04, 0.61 ± 0.04, and CN s of 0.33 ± 0.06, 0.55 ± 0.04, 0.60 ± 0.04 for CRT , IMRT , and VMAT , respectively. IMRT and VMAT decreased the dose to bladder and rectum significantly compared with CRT . No significant differences on the Dmean, V45, and V30 of small bowel were observed among CRT , IMRT , and VMAT . However, VMAT (10.4 ± 4.8 vs. 19.8 ± 11.0, P  = 0.004) and IMRT (12.3 ± 5.0 vs. 19.8 ± 11.0, P  = 0.02) decreased V40, increased the Dmax of small bowel and the irradiation dose to femoral heads compared with CRT . VMAT irradiated less dose to bladder, rectum, small bowel and larger volume of health tissue with a lower dose (V5 and V10) compared with IMRT , although the differences were not statistical significant. In conclusion, VMAT and IMRT showed significant dosimetric advantages both on target coverage and OAR sparing compared with CRT in the treatment of postoperative cervical cancer. However, no significant difference between IMRT and VMAT was observed except for slightly better dose conformity, slightly less MU , and significant shorter delivery time achieved for VMAT .
    Type of Medium: Online Resource
    ISSN: 1526-9914 , 1526-9914
    URL: Issue
    URL: Article
    DOI: 10.1002/acm2.2017.18.issue-1
    DOI: 10.1002/acm2.12003
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 2010347-5
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