In:
Ophthalmic Surgery, Lasers and Imaging Retina, SLACK, Inc., Vol. 40, No. 2 ( 2009-01), p. 96-101
Abstract:
〈 div class="ftSection" 〉 〈 span class="ftInlineSubsectionTitle" 〉 Background and Objective: 〈 /span 〉 〈 p 〉 To compare images of geographic atrophy (GA) obtained using spectral domain optical coherence tomography (SD-OCT) with images obtained using fundus autofluorescence (FAF). 〈 /p 〉 〈 /div 〉 〈 div class="ftSection" 〉 〈 span class="ftInlineSubsectionTitle" 〉 Patients and Methods: 〈 /span 〉 〈 p 〉 Five eyes from patients with dry AMD were imaged using SD-OCT and FAF, and the size and shape of the GA were compared. 〈 /p 〉 〈 /div 〉 〈 div class="ftSection" 〉 〈 span class="ftInlineSubsectionTitle" 〉 Results: 〈 /span 〉 〈 p 〉 GA appears bright on SD-OCT compared with the surrounding areas with an intact retinal pigment epithelium because of increased reflectivity from the underlying choroid. SD-OCT and FAF both identified GA reproducibly, and measurement of the area of GA is comparable between the two methods with a mean difference of 2.7% of the total area. 〈 /p 〉 〈 /div 〉 〈 div class="ftSection" 〉 〈 span class="ftInlineSubsectionTitle" 〉 Conclusion: 〈 /span 〉 〈 p 〉 SD-OCT can identify and quantitate areas of GA. The size and shape of these areas correlate well to the areas of GA seen on autofluorescence images; however, SD-OCT imaging also provides important cross-sectional anatomic information. 〈 /p 〉 〈 /div 〉
Type of Medium:
Online Resource
ISSN:
2325-8160
,
2325-8179
DOI:
10.3928/15428877-20090301-16
Language:
English
Publisher:
SLACK, Inc.
Publication Date:
2009
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