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  • 1
    Online Resource
    Online Resource
    Norwegian University of Science and Technology (NTNU) Library ; 2014
    In:  Norsk Epidemiologi Vol. 24, No. 1-2 ( 2014-12-29)
    In: Norsk Epidemiologi, Norwegian University of Science and Technology (NTNU) Library, Vol. 24, No. 1-2 ( 2014-12-29)
    Abstract: Aims: To study information on prescribed drug use (opioids, antidepressants and benzodiazepines (BZD)) recorded in the Norwegian Prescription Database (NorPD) and to compare this information with selfreported drug use among pregnant women in the Norwegian Mother and Child Cohort Study (MoBa).Materials and methods: The study population consisted of 28 479 women who participated in MoBa and who answered all questionnaires in pregnancy and whose pregnancy started after 1 March 2004. Data on dispensed drugs in NorPD were extracted for three different time windows: a) the pregnancy period, b) 30 days prior to pregnancy in addition to pregnancy, c) 60 days prior to pregnancy in addition to pregnancy. Data on self- reported drug use in MoBa were used as the reference standard in the validity analysis. Sensitivity and specificity were calculated.Results: Sensitivity of drug use as recorded in NorPD for the pregnancy period was highest for antidepressants (66.9%) and BZD-antiepileptics (100%) and lowest for BZD-anxiolytics (44.8%) and BZDhypnotics (27.8%). Expansion of the time windows for dispensed drugs in the NorPD to include intervals 30 and 60 days before pregnancy led to higher sensitivity, but lower specificity of all classes of drugs. For opioids, sensitivity increased from 48.8% to 53.6%, while specificity decreased from 98.7 to 97.6%. For antidepressants and BZD-anxiolytics, specificity decreased for both from 99.7 to 99.4%.Conclusion: Using self-reported data as reference standard, the prescription data provides valid information on current exposures to BZD-antiepileptics and antidepressants in pregnant women if time windows are selected with adequate consideration depending on the investigated problem. However, validity is lower for other benzodiazepines and opioids.
    Type of Medium: Online Resource
    ISSN: 0803-2491
    Language: Unknown
    Publisher: Norwegian University of Science and Technology (NTNU) Library
    Publication Date: 2014
    detail.hit.zdb_id: 2379279-6
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  • 2
    Online Resource
    Online Resource
    Norwegian University of Science and Technology (NTNU) Library ; 2009
    In:  Norsk Epidemiologi Vol. 13, No. 2 ( 2009-10-15)
    In: Norsk Epidemiologi, Norwegian University of Science and Technology (NTNU) Library, Vol. 13, No. 2 ( 2009-10-15)
    Abstract: -
    Type of Medium: Online Resource
    ISSN: 0803-2491
    Language: Unknown
    Publisher: Norwegian University of Science and Technology (NTNU) Library
    Publication Date: 2009
    detail.hit.zdb_id: 2379279-6
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  • 3
    Online Resource
    Online Resource
    Norwegian University of Science and Technology (NTNU) Library ; 2021
    In:  Norsk Epidemiologi Vol. 29, No. 1-2 ( 2021-08-16)
    In: Norsk Epidemiologi, Norwegian University of Science and Technology (NTNU) Library, Vol. 29, No. 1-2 ( 2021-08-16)
    Abstract: -
    Type of Medium: Online Resource
    ISSN: 0803-2491
    Language: Unknown
    Publisher: Norwegian University of Science and Technology (NTNU) Library
    Publication Date: 2021
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  • 4
    Online Resource
    Online Resource
    Norwegian University of Science and Technology (NTNU) Library ; 2009
    In:  Norsk Epidemiologi Vol. 7, No. 2 ( 2009-10-26)
    In: Norsk Epidemiologi, Norwegian University of Science and Technology (NTNU) Library, Vol. 7, No. 2 ( 2009-10-26)
    Abstract:  SAMMENDRAGBetydningen av ekteskapelig status for risikofaktorer og dødelighet av hjerte-karsykdommer og alle årsakerhar blitt studert hos menn og kvinner som var 35-49 år ved innkalling til hjerte-karundersøkelse. Andelensom mottok uførepensjon, var høyere blant ugifte enn gifte. Etter eksklusjon av uførepensjonerte og hjertekarsykevar systolisk og diastolisk blodtrykk høyere hos ugifte enn gifte, både for menn og kvinner. Andeldagligrøykere var klart høyest blant skilte/separerte. Gifte menn var mest fysisk aktive i fritiden. Justert foralder, dagligrøyking, diastolisk blodtrykk, serum totalkolesterol, kroppshøyde, kroppsmasseindeks ogfysisk aktivitet i fritiden, hadde ugifte og skilte/separerte menn en relativ risiko for totaldød i forhold tilgifte på henholdsvis 1,32 (95% konfidensintervall (KI): 1,17–1,49) og 1,46 (KI: 1,08–1,95). Ugifte kvinnerhadde en justert relativ risiko i forhold til gifte kvinner på 1,32 (KI: 1,01–1,73). Ugifte menn hadde høyeredødelighet av hjerneslag enn gifte menn, med en justert relativ risiko på 1,72 (KI: 1,02–2,89). Ugifte mennhadde ingen signifikant overdødelighet av koronar hjertesykdom i forhold til gifte menn etter justering,men for alle hjerte-karsykdommer samlet, hadde ugifte menn en justert relativ risiko på 1,28 (KI:1,07–1,53) i forhold til gifte.Selmer RM. Marital status, risk factors and total and cardiovascular mortality. An 18-year follow-upstudy of 28,170 men and 26,235 women in three Norwegian counties.Nor J Epidemiol ENGLISH SUMMARYThe relationship between marital status, risk factors and total and cardiovascular mortality has been studiedin a total of 28,170 men and 26,235 women who, at the age of 35-49 years were invited to the firstcardiovascular screening in Finnmark (1974-75), Sogn og Fjordane (1975-76) and Oppland (1976-78). Ahigher percentage of unmarried than married men and women received disability pensions. After excludingpeople receiving disability pensions and people with known cardiovascular disease at screening, systolicblood pressure was 6 mm higher in unmarried than in married men and 4 mm higher in unmarried than inmarried women. For diastolic blood pressure the differences were 3 mm in men and 2 mm in women. Thepercentage of men who smoked daily was highest amongst those divorced/separated (70%) and lowestamongst the married men (52%). The percentage of female daily smokers was highest amongstdivorced/separated women (60%) and lowest amongst the unmarried (31%). Married men were more oftenthan other groups physically active during leisure. Unmarried and divorced/separated men had higher totalmortality than married men after adjusting for age, daily smoking (yes/no), diastolic blood pressure, serumtotal cholesterol, body height, body mass index and physical activity during leisure (coded 1-4) with arelative risk of RR = 1.32 (95% confidence interval (CI) 1.17–1.49) in unmarried men and RR = 1.46 (CI:1.08–1.95) in those divorced/separated. Unmarried women had an adjusted relative risk of total mortalityversus married women of 1.32 (95% CI: 1.01–1.73). Unmarried men had an adjusted relative risk of deathfrom cerebrovascular diseases versus married men of 1.72 (95% CI: 1.02–2.89). After adjustment therewas no significant excess mortality from coronary heart disease in unmarried versus married men, butunmarried men had an adjusted relative risk of death from all cardiovascular causes of 1.28 (95% CI:1.07–1.53) versus married men.1997; 7 (2): 213-219.
    Type of Medium: Online Resource
    ISSN: 0803-2491
    Language: Unknown
    Publisher: Norwegian University of Science and Technology (NTNU) Library
    Publication Date: 2009
    detail.hit.zdb_id: 2379279-6
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  • 5
    In: European Journal of Endocrinology, Oxford University Press (OUP), Vol. 155, No. 5 ( 2006-11), p. 693-699
    Abstract: Objective : To evaluate whether Pakistanis have increased bone turnover compared with ethnic Norwegians due to their high prevalence of vitamin D deficiency and secondary hyperparathyroidism, and whether the relation between bone turnover and bone mineral density (BMD) differs between Pakistanis and ethnic Norwegians. Design : A cross-sectional, population-based study conducted in the city of Oslo in 2000–2001. Random samples of 132 community-dwelling Pakistani men and women of ages 40, 45, and 59–60 years, and 580 community-dwelling Norwegian men and women of ages 45 and 59–60 years are included in this substudy. Methods : Venous serum samples were drawn for measurements of markers of the vitamin D endocrine system and the bone turnover markers osteocalcin (s-OC), bone alkaline phosphatase (s-bone ALP), and tartrate-resistant acid phosphatase (s-TRACP). BMD was measured at the forearm by single-energy X-ray absorptiometry. Results : Pakistanis had higher s-bone ALP compared with Norwegians. Mean (95% CI) age-adjusted levels were 22.5 (21.0, 24.1) U/l in Pakistani men versus 19.3 (18.6, 20.1) U/l in Norwegian men, P 〈 0.0005, and 20.3 (18.4, 22.1) U/l in Pakistani women versus 16.7 (16.0, 17.4) U/l in Norwegian women, P = 0.001. There tended to be an inverse association between bone turnover and BMD in men and women of both ethnic groups, and it was strongest for s-bone ALP. Overall mean (95% CI) distal BMD decrease was −16 (−20, −11) mg/cm 2 per 1 s.d . increase in s-bone ALP ( P 〈 0.0005) when adjusting for age, sex, and ethnicity. Conclusions : Except for somewhat higher s-bone ALP levels in Pakistanis, there were only minor ethnic differences in bone turnover, despite a strikingly different prevalence of secondary hyperparathyroidism. Bone turnover was inversely associated with forearm BMD in both ethnic groups.
    Type of Medium: Online Resource
    ISSN: 0804-4643 , 1479-683X
    RVK:
    Language: Unknown
    Publisher: Oxford University Press (OUP)
    Publication Date: 2006
    detail.hit.zdb_id: 1485160-X
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  • 6
    Online Resource
    Online Resource
    Norwegian University of Science and Technology (NTNU) Library ; 2011
    In:  Norsk Epidemiologi Vol. 13, No. 1 ( 2011-10-24)
    In: Norsk Epidemiologi, Norwegian University of Science and Technology (NTNU) Library, Vol. 13, No. 1 ( 2011-10-24)
    Abstract: -
    Type of Medium: Online Resource
    ISSN: 0803-2491
    Language: Unknown
    Publisher: Norwegian University of Science and Technology (NTNU) Library
    Publication Date: 2011
    detail.hit.zdb_id: 2379279-6
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  • 7
    Online Resource
    Online Resource
    Norwegian University of Science and Technology (NTNU) Library ; 2012
    In:  Norsk Epidemiologi Vol. 22, No. 2 ( 2012-11-29)
    In: Norsk Epidemiologi, Norwegian University of Science and Technology (NTNU) Library, Vol. 22, No. 2 ( 2012-11-29)
    Abstract: Background: The prevalence of dementia is expected to increase markedly during the coming decades. Epidemiological studies involving the National Cause of Death Registry (NCDR) may be useful for exploring the aetiology of dementia. We therefore wanted to study developments in the reporting of dementia in the NCDR over the last four decades.Methods: We calculated the age- and gender specific proportion of deaths with dementia reported in the NCDR (dementia deaths) in the period 1969-2010, and the proportion of vascular dementia and Alzheimer’s disease deaths in 1986-2010. Separate analyses were done for deaths occurring in nursing homes in 1996-2010. The proportion of dementia deaths where dementia was coded as underlying cause of death was also calculated.Results: The proportion of dementia deaths increased more than threefold in the period 1969-2010 among women (from 4% to 15%), and more than doubled among men (from 3% to 7%). In nursing homes the proportion increased from 17% to 26% for women and from 13% to 18% for men. The proportion of dementia deaths with Alzheimer’s disease reported in the NCDR increased from practically zero in 1986 to a maximum of 28% in 2005. The proportion of dementia deaths with dementia as underlying cause of death increased from a minimum of 6% in 1972 to a maximum of 51% in 2009.Conclusion: Although the reporting of dementia in the NCDR increased markedly from 1969 to 2010, dementia is still under-reported for old people and for deaths occurring in nursing homes when compared to prevalence estimates.
    Type of Medium: Online Resource
    ISSN: 0803-2491
    Language: Unknown
    Publisher: Norwegian University of Science and Technology (NTNU) Library
    Publication Date: 2012
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  • 8
    Online Resource
    Online Resource
    Norwegian University of Science and Technology (NTNU) Library ; 2011
    In:  Norsk Epidemiologi Vol. 13, No. 1 ( 2011-10-24)
    In: Norsk Epidemiologi, Norwegian University of Science and Technology (NTNU) Library, Vol. 13, No. 1 ( 2011-10-24)
    Abstract: -
    Type of Medium: Online Resource
    ISSN: 0803-2491
    Language: Unknown
    Publisher: Norwegian University of Science and Technology (NTNU) Library
    Publication Date: 2011
    detail.hit.zdb_id: 2379279-6
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  • 9
    Online Resource
    Online Resource
    Norwegian University of Science and Technology (NTNU) Library ; 2022
    In:  Norsk Epidemiologi Vol. 30, No. 1-2 ( 2022-10-12)
    In: Norsk Epidemiologi, Norwegian University of Science and Technology (NTNU) Library, Vol. 30, No. 1-2 ( 2022-10-12)
    Abstract: The Cancer Registry of Norway (CRN) has been important in registry-based research in Norway for decades. The use of CRN in combination with other population-based registries and health surveys have been the basis for numerous research projects, which has contributed to fill important knowledge gaps. Researchers at the Norwegian Institute of Public Health and CRN have a long tradition of using these data sources to address research questions of common interests such as e.g. the effect of life style and diet on cancer risk. CRN and the Medical Birth Registry of Norway have co-existed for a long period, making it possible to study cancer incidence and birth characteristics over generations. During the last decades, several new registries such as the Norwegian Prescription Database and the Norwegian Patient Registry have been established, providing opportunities for studying for example drug use and cancer risk and the influence of comorbidities on the development of cancer. In the future, the CRN will be an even more valuable data source when also other population-based registries and health surveys have existed for longer time periods.
    Type of Medium: Online Resource
    ISSN: 0803-2491
    Language: Unknown
    Publisher: Norwegian University of Science and Technology (NTNU) Library
    Publication Date: 2022
    detail.hit.zdb_id: 2379279-6
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